Results 11 to 20 of about 76,553 (211)
Molecular BioSystems, 2012 Abstract Proteoglycans (PGs) are among the most structurally complex biomacromolecules in nature. They are present in all animal cells and frequently exert their critical biological functions through interactions with proteinligands and receptors.
Lingyun, Li +2 more
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Seminars in Cell & Developmental Biology, 2001 The predominant proteoglycan present in cartilage is the large chondroitin sulfate proteoglycan 'aggrecan'. Following its secretion, aggrecan self-assembles into a supramolecular structure with as many as 50 monomers bound to a filament of hyaluronan.
C B, Knudson, W, Knudson
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Intracellular proteoglycans [PDF]
Biochemical Journal, 2004 Proteoglycans (PGs) are proteins with glycosaminoglycan chains, are ubiquitously expressed and have a wide range of functions. PGs in the extracellular matrix and on the cell surface have been the subject of extensive structural and functional studies.
Svein Olav, Kolset +2 more
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Angiotensin II Induces Aortic Rupture and Dissection in Osteoprotegerin‐Deficient Mice
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022 Background The biological mechanism of action for osteoprotegerin, a soluble decoy receptor for the receptor activator of nuclear factor‐kappa B ligand in the vascular structure, has not been elucidated.
Toshihiro Tsuruda +12 more
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Frontiers in Immunology, 2020 The attachment of a variety of Lactobacilli to the mucosal surfaces is accomplished through the interaction of OppA, a superficial bacterial protein also involved in oligopeptide internalization, and the glycosaminoglycan moiety of the proteoglycans that
Carla Martín +9 more
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Biglycan : a multivalent proteoglycan providing structure and signals [PDF]
, 2013 Research over the past few years has provided fascinating results indicating that biglycan, besides being a ubiquitous structural component of the extracellular matrix (ECM), may act as a signaling molecule.
Schäfer, Liliana +2 more
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Quantification of collagen and proteoglycan deposition in a murine model of airway remodelling [PDF]
, 2005 Background: Sub- epithelial extracellular matrix deposition is a feature of asthmatic airway remodelling associated with severity of disease, decline in lung function and airway hyperresponsiveness.
Reinhardt Alistair K +11 more
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Frontiers in Oncology, 2014 Heparan sulfates (HS) are key components of mammalian cells surface and extracellular matrix. Structure and composition of HS, generated by HS biosynthetic system through non-template driven process, are significantly altered in cancer tissues.
Anastasia V Suhovskih +8 more
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Proteoglycans and Osteolysis [PDF]
, 2011 Osteolysis is a complex mechanism resulting from an exacerbated activity of osteoclasts associated or not with a dysregulation of osteoblast metabolism leading to bone loss. This bone defect is not compensated by bone apposition or by apposition of bone matrix with poor mechanical quality.
Baud'Huin, Marc +6 more
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Supramolecular structure of a new family of circular proteoglycans mediating cell adhesion in sponges [PDF]
, 2000 Jarchow J, Fritz J, Anselmetti D, et al. Supramolecular structure of a new family of circular proteoglycans mediating cell adhesion in sponges. Journal of structural biology.
Fritz, Jürgen +7 more
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