Results 21 to 30 of about 111,979 (309)

Glycosaminoglycans and Proteoglycans [PDF]

open access: yesPharmaceuticals, 2018
In this editorial to MDPI Pharmaceuticals special issue “Glycosaminoglycans and Proteoglycans” we describe in outline the common structural features of glycosaminoglycans and the characteristics of proteoglycans, including the intracellular proteoglycan, serglycin, cell-surface proteoglycans, like syndecans and glypicans, and the extracellular matrix ...
Vitor Pomin, Barbara Mulloy
openaire   +3 more sources

Chemotherapy-Induced Degradation of Glycosylated Components of the Brain Extracellular Matrix Promotes Glioblastoma Relapse Development in an Animal Model

open access: yesFrontiers in Oncology, 2021
Adjuvant chemotherapy with temozolomide (TMZ) is an intrinsic part of glioblastoma multiforme (GBM) therapy targeted to eliminate residual GBM cells.
Alexandra Y. Tsidulko   +11 more
doaj   +1 more source

Heparan sulfate proteoglycan as a cell-surface endocytosis receptor.

open access: yesMatrix Biology, 2014
How various macromolecules are exchanged between cells and how they gain entry into recipient cells are fundamental questions in cell biology with important implications e.g.
H. Christianson, M. Belting
semanticscholar   +1 more source

Decoding the matrix: Instructive roles of proteoglycan receptors

open access: yesBiochemistry, 2015
The extracellular matrix is a dynamic repository harboring instructive cues that embody substantial regulatory dominance over many evolutionarily conserved intracellular activities including proliferation, apoptosis, migration, motility, and autophagy ...
T. Neill, L. Schaefer, R. Iozzo
semanticscholar   +1 more source

Extracellular Matrix of Echinoderms

open access: yesMarine Drugs, 2023
This review considers available data on the composition of the extracellular matrix (ECM) in echinoderms. The connective tissue in these animals has a rather complex organization.
Igor Yu. Dolmatov   +1 more
doaj   +1 more source

PTPσ Is a Receptor for Chondroitin Sulfate Proteoglycan, an Inhibitor of Neural Regeneration

open access: yesScience, 2009
Toward Neuronal Regeneration Neurons in the central nervous system that are severed or crushed do not regenerate well. Part of the problem derives from the glial scars left behind after such damage.
Yingjie Shen   +8 more
semanticscholar   +1 more source

Endocan: A novel circulating proteoglycan

open access: yesIndian Journal of Pharmacology, 2014
Endocan is a novel endothelium derived soluble dermatan sulfate proteoglycan. It has the property of binding to a wide range of bioactive molecules associated with cellular signaling and adhesion and thus regulating proliferation, differentiation ...
A. Kali, K. Shetty
semanticscholar   +1 more source

Proteoglycans and catabolic products of proteoglycans present in ligament [PDF]

open access: yesBiochemical Journal, 2005
The aim of the present study was to characterize the proteoglycans and catabolic products of proteoglycans present in the tensile region of ligament and explant cultures of this tissue, and to compare these with those observed in the tensile region of tendon. Approx.
Ilic, Mirna Z.   +4 more
openaire   +2 more sources

The central role of vascular extracellular matrix and basement membrane remodeling in metabolic syndrome and type 2 diabetes: the matrix preloaded

open access: yesCardiovascular Diabetology, 2005
The vascular endothelial basement membrane and extra cellular matrix is a compilation of different macromolecules organized by physical entanglements, opposing ionic charges, chemical covalent bonding, and cross-linking into a biomechanically active ...
Tyagi Suresh C   +2 more
doaj   +1 more source

The Effect of Intense Exercise on Equine Serum Proteoglycan-4/Lubricin

open access: yesFrontiers in Veterinary Science, 2020
Objective: Local biological and biomechanical-stimuli modulate proteoglycan-4 secretion within synovial joints. For the horse, changes to proteoglycan-4 concentration and function are notable in acute joint injury and osteoarthritis. Proteoglycan-4 (also
Austyn Matheson   +5 more
doaj   +1 more source

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