Results 1 to 10 of about 22,801 (226)

Mucopolysaccharidosis IVA: Diagnosis, Treatment, and Management. [PDF]

, 2020
Mucopolysaccharidosis type IVA (MPS IVA, or Morquio syndrome type A) is an inherited metabolic lysosomal disease caused by the deficiency of the N-acetylglucosamine-6-sulfate sulfatase enzyme.
Couce, Maria L., Otero, Francisco J., Piechnik, Matthew, Sawamoto, Kazuki, Suzuki, Yasuyuki, Tomatsu, Shunji, Álvarez González, José Víctor   +6 more
core   +2 more sources

Drug delivery in overcoming the blood-brain barrier: role of nasal mucosal grafting [PDF]

, 2017
The blood–brain barrier (BBB) plays a fundamental role in protecting and maintaining the homeostasis of the brain. For this reason, drug delivery to the brain is much more difficult than that to other compartments of the body. In order to bypass or cross
Carafa, Maria, Di Marzio, Luisa, Hanieh, PATRIZIA NADIA, Marianecci, Carlotta, Paolino, Donatella, Rinaldi, Federica   +5 more
core   +1 more source

International guidelines for the management and treatment of Morquio A syndrome. [PDF]

, 2014
Morquio A syndrome (mucopolysaccharidosis IVA) is a lysosomal storage disorder associated with skeletal and joint abnormalities and significant non-skeletal manifestations including respiratory disease, spinal cord compression, cardiac disease, impaired ...
Berger, Kenneth I, Giugliani, Roberto, Harmatz, Paul, Hendriksz, Christian J, Kampmann, Christoph, Mackenzie, William G, Raiman, Julian, Savarirayan, Ravi, Villarreal, Martha Solano   +8 more
core   +2 more sources

Metabolomics application in maternal-fetal medicine [PDF]

, 2013
Metabolomics in maternal-fetal medicine is still an "embryonic" science. However, there is already an increasing interest in metabolome of normal and complicated pregnancies, and neonatal outcomes. Tissues used for metabolomics interrogations of pregnant
Atzori, L, Fanos, V, Ferrazzi, E, Makarenko, K, Melis, GB   +4 more
core   +4 more sources

Comparative genomics and mutagenesis analyses of choline metabolism in the marine Roseobacter clade [PDF]

, 2015
Choline is ubiquitous in marine eukaryotes and appears to be widely distributed in surface marine waters; however, its metabolism by marine bacteria is poorly understood.
Andresen P.A., Gauthier M.J., Ghoul M., Ikawa M., Kiene R.P., Nau‐Wagner G., Prado S.   +6 more
core   +1 more source

Sulfatase‐mediated manipulation of the astrocyte‐Schwann cell interface [PDF]

, 2017
Schwann cell (SC) transplantation following spinal cord injury (SCI) may have therapeutic potential. Functional recovery is limited however, due to poor SC interactions with host astrocytes and the induction of astrogliosis.
Afshari, Ai, Ai, Ai, Barnett, Barnett, Barraud, Battaglia, Bernfield, Blakemore, Blakemore, Bottenstein, Campana, Carey, Dai, Davis, Dhoot, Doucette, Dull, Duncan, Eliasson, Faye, Franceschini, Franklin, Freeman, Gallagher, Ghirnikar, Gill, Gomez-Pinilla, Gudi, Guimond, Gómez-Pinilla, Hendriks, Higginson, Hou, Ieguchi, Imaizumi, Iwashita, Iwashita, Johnson-Green, Kalus, Kalus, Kang, Kim, Lakatos, Lakatos, Lamanna, Lamanna, Leadbeater, Li, Logan, Mahanthappa, Martin, Meintanis, Milner, Naldini, Otsuki, Pankonin, Pearse, Petroski, Pollock, Raff, Raisman, Ramón-Cueto, Ratner, Reilly, Rutkowski, Santos-Silva, Shannon, Shields, Smith, Somanath, Soung, Sudhalter, Tabakow, Toft, Tokita, Turnbull, Wang, Watabe, Wilby, Witheford   +81 more
core   +3 more sources

Discovery of a novel iota carrageenan sulfatase isolated from the marine bacterium Pseudoalteromonas carrageenovora

Frontiers in Chemistry, 2014
Carrageenans are sulfated polysaccharides extracted from the cell wall of some marine red algae. These polysaccharides are widely used as gelling, stabilizing, and viscosifying agents in the food and pharmaceutical industries.
Sabine Marie Genicot, Sabine Marie Genicot, Agnès eGroisillier, Agnès eGroisillier, Hélène eRogniaux, Laurence eMeslet-Cladière, Laurence eMeslet-Cladière, Laurence eMeslet-Cladière, Tristan eBarbeyron, Tristan eBarbeyron, William eHelbert, William eHelbert, William eHelbert   +12 more
doaj   +1 more source

Chromosome assignment of two cloned DNA probes hybridizing predominantly to human sex chromosomes [PDF]

, 1984
In situ hybridization experiments were carried out with two clones, YACG 35 and 2.8, which had been selected from two genomic libraries strongly enriched for the human Y chromosome.
A Chapelle de la, AJ Solari, AJ Solari, BD Young, BR Migeon, C Cremer, CR M�ller, CR M�ller, D Page, DT Denhardt, EMJ Southern, GM Wahl, J Fantes, JBS Haldane, JW Gray, KE Davies, L Zech, LM Kunkel, LM Kunkel, MJ Moses, P Goodfellow, P Leder, P Polani, PK Horan, PL Pearson, PN Dean, PN Dean, PN Goodfellow, PS Burgoyne, PS Gerhard, R Krumlauf, RG Langlois, SP Daiger, T Mohandas, U M�ller   +34 more
core   +1 more source

Cloning and Characterization of a Novel N-Acetyl-D-galactosamine-4-O-sulfate Sulfatase, SulA1, from a Marine Arthrobacter Strain

Marine Drugs
Sulfation is gaining increased interest due to the role of sulfate in the bioactivity of many polysaccharides of marine origin. Hence, sulfatases, enzymes that control the degree of sulfation, are being more extensively researched.
Monica Daugbjerg Christensen, Leila Allahgholi, Javier A. Linares-Pastén, Ólafur Friðjónsson, Hörður Guðmundsson, Varsha Kale, Roya R. R. Sardari, Guðmundur Ó. Hreggviðsson, Eva Nordberg Karlsson   +8 more
doaj   +1 more source

Identification and Signature Sequences of Bacterial Δ4,5Hexuronate-2-O-Sulfatases

Frontiers in Microbiology, 2019
Glycosaminoglycan (GAG) sulfatases, which catalyze the hydrolysis of sulfate esters from GAGs, belong to a large and conserved sulfatase family. Bacterial GAG sulfatases are essential in the process of sulfur cycling and are useful for the structural ...
Shumin Wang, Jingwen Guan, Qingdong Zhang, Xiangxue Chen, Fuchuan Li   +4 more
doaj   +1 more source