Results 21 to 30 of about 15,873 (215)

Sulfotransferases and Sulfatases in Mycobacteria [PDF]

open access: yesChemistry & Biology, 2002
Analysis of the genomes of M. tuberculosis, M. leprae, M. smegmatis, and M. avium has revealed a large family of genes homologous to known sulfotransferases. Despite reports detailing a suite of sulfated glycolipids in many mycobacteria, a corresponding family of sulfotransferase genes remains uncharacterized.
Mougous, Joseph D   +4 more
openaire   +2 more sources

Purification, Characterization, and Structural Studies of a Sulfatase from Pedobacter yulinensis

open access: yesMolecules, 2021
Sulfatases are ubiquitous enzymes that hydrolyze sulfate from sulfated organic substrates such as carbohydrates, steroids, and flavones. These enzymes can be exploited in the field of biotechnology to analyze sulfated metabolites in humans, such as ...
Caleb R. Schlachter   +5 more
doaj   +1 more source

Between the Devil and the Deep Blue Sea—Resveratrol, Sulfotransferases and Sulfatases—A Long and Turbulent Journey from Intestinal Absorption to Target Cells

open access: yesMolecules, 2023
For nearly 30 years, resveratrol has attracted the scientific community’s interest. This has happened thanks to the so-called French paradox, that is, the paradoxically low mortality from cardiovascular causes in the French population despite a diet rich
Izabela Szymkowiak   +2 more
doaj   +1 more source

Unraveling Heparan Sulfate Proteoglycan Binding Motif for Cancer Cell Selectivity

open access: yesFrontiers in Oncology, 2019
Membrane heparan sulfate proteoglycans (HSPG) regulate cell proliferation, migration, and differentiation and are therefore considered key players in cancer cell development processes.
Jlenia Brunetti   +9 more
doaj   +1 more source

Estrogen Formation and Inactivation Following TBI: What we Know and Where we Could go

open access: yesFrontiers in Endocrinology, 2020
Traumatic brain injury (TBI) is responsible for various neuronal and cognitive deficits as well as psychosocial dysfunction. Characterized by damage inducing neuroinflammation, this response can cause an acute secondary injury that leads to widespread ...
Kelli A. Duncan
doaj   +1 more source

Sulfatases: Critical Enzymes for Algal Polysaccharide Processing

open access: yesFrontiers in Plant Science, 2022
Microbial sulfatases are important biocatalysts in the marine environment where they play a key role in the catabolic biotransformation of abundant sulphated algal polysaccharides. The sulphate esters decorating algal polysaccharides, such as carrageenan,
Andrew G. Hettle   +2 more
doaj   +1 more source

Enhanced levels of Hsulf-1 interfere with heparin-binding growth factor signaling in pancreatic cancer

open access: yesMolecular Cancer, 2005
Hsulf-1 is a newly identified enzyme, which has the ability to decrease the growth of hepatocellular, ovarian, and head and neck squamous cell carcinoma cells by interfering with heparin-binding growth factor signaling.
Giese Nathalia A   +8 more
doaj   +1 more source

Sulfatase 1 and sulfatase 2 as novel regulators of macrophage antigen presentation and phagocytosis [PDF]

open access: yesYeungnam University Journal of Medicine, 2021
Background Sulfation of heparan sulfate proteoglycans (HSPGs) is critical for the binding and signaling of ligands that mediate inflammation. Extracellular 6-O-endosulfatases regulate posttranslational sulfation levels and patterns of HSPGs.
Hyun-Je Kim   +2 more
doaj   +1 more source

Post-synthetic regulation of HS structure: the yin and yang of the Sulfs in Cancer

open access: yesFrontiers in Oncology, 2014
Heparan sulfate (HS) is a complex polysaccharide that takes part in most major cellular processes, through its ability to bind and modulate a very large array of proteins.
Romain R Vives   +2 more
doaj   +1 more source

The Effect of Glucosinolates on the Growth and Development of Helicoverpa armigera Larvae and the Expression of Midgut Sulfatase Genes

open access: yesAgronomy, 2022
The plant–pest interaction and its mechanisms are a novel research direction for pest control. They provide molecular targets for developing new pesticides and targeted control measures to control insect herbivores.
Xue Li   +7 more
doaj   +1 more source

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