Results 31 to 40 of about 22,801 (226)

Estrogen Formation and Inactivation Following TBI: What we Know and Where we Could go

Frontiers in Endocrinology, 2020
Traumatic brain injury (TBI) is responsible for various neuronal and cognitive deficits as well as psychosocial dysfunction. Characterized by damage inducing neuroinflammation, this response can cause an acute secondary injury that leads to widespread ...
Kelli A. Duncan
doaj   +1 more source

Between the Devil and the Deep Blue Sea—Resveratrol, Sulfotransferases and Sulfatases—A Long and Turbulent Journey from Intestinal Absorption to Target Cells

Molecules, 2023
For nearly 30 years, resveratrol has attracted the scientific community’s interest. This has happened thanks to the so-called French paradox, that is, the paradoxically low mortality from cardiovascular causes in the French population despite a diet rich
Izabela Szymkowiak, Malgorzata Kucinska, Marek Murias   +2 more
doaj   +1 more source

Unraveling Heparan Sulfate Proteoglycan Binding Motif for Cancer Cell Selectivity

Frontiers in Oncology, 2019
Membrane heparan sulfate proteoglycans (HSPG) regulate cell proliferation, migration, and differentiation and are therefore considered key players in cancer cell development processes.
Jlenia Brunetti, Giulia Riolo, Lorenzo Depau, Elisabetta Mandarini, Andrea Bernini, Evgenia Karousou, Alberto Passi, Alessandro Pini, Luisa Bracci, Chiara Falciani   +9 more
doaj   +1 more source

Sulfatases: Critical Enzymes for Algal Polysaccharide Processing

Frontiers in Plant Science, 2022
Microbial sulfatases are important biocatalysts in the marine environment where they play a key role in the catabolic biotransformation of abundant sulphated algal polysaccharides. The sulphate esters decorating algal polysaccharides, such as carrageenan,
Andrew G. Hettle, Chelsea J. Vickers, Alisdair B. Boraston   +2 more
doaj   +1 more source

Sulfatase 1 and sulfatase 2 as novel regulators of macrophage antigen presentation and phagocytosis [PDF]

Yeungnam University Journal of Medicine, 2021
Background Sulfation of heparan sulfate proteoglycans (HSPGs) is critical for the binding and signaling of ligands that mediate inflammation. Extracellular 6-O-endosulfatases regulate posttranslational sulfation levels and patterns of HSPGs.
Hyun-Je Kim, Hee-Sun Kim, Young-Hoon Hong   +2 more
doaj   +1 more source

Enhanced levels of Hsulf-1 interfere with heparin-binding growth factor signaling in pancreatic cancer

Molecular Cancer, 2005
Hsulf-1 is a newly identified enzyme, which has the ability to decrease the growth of hepatocellular, ovarian, and head and neck squamous cell carcinoma cells by interfering with heparin-binding growth factor signaling.
Giese Nathalia A, Kayed Hany, Abiatari Ivane, Kleeff Jörg, Li Junsheng, Felix Klaus, Giese Thomas, Büchler Markus W, Friess Helmut   +8 more
doaj   +1 more source

Alterations in hepatic miRNA expression during negative energy balance in postpartum dairy cattle [PDF]

, 2014
peer-reviewedBackground Negative energy balance (NEB), an altered metabolic state, occurs in early postpartum dairy cattle when energy demands to support lactation exceed energy intake.
Fatima, Attia, Morris, Dermot G., O'Boyle, Padraig, Seoighe, Cathal, Waters, Sinead M.   +4 more
core   +1 more source

Post-synthetic regulation of HS structure: the yin and yang of the Sulfs in Cancer

Frontiers in Oncology, 2014
Heparan sulfate (HS) is a complex polysaccharide that takes part in most major cellular processes, through its ability to bind and modulate a very large array of proteins.
Romain R Vives, Amal eSeffouh, Hugues eLortat-Jacob   +2 more
doaj   +1 more source

The Effect of Glucosinolates on the Growth and Development of Helicoverpa armigera Larvae and the Expression of Midgut Sulfatase Genes

Agronomy, 2022
The plant–pest interaction and its mechanisms are a novel research direction for pest control. They provide molecular targets for developing new pesticides and targeted control measures to control insect herbivores.
Xue Li, Fan Cai, Guli Kuerban, Shaohui Zhang, Chaoyong Li, Ying Zhao, Lin Jin, Xiaoli Ma   +7 more
doaj   +1 more source

Resveratrol given intraperitoneally does not inhibit the growth of high-risk t(4;11) acute lymphoblastic leukemia cells in a NOD/SCID mouse model. [PDF]

, 2011
The efficacy of resveratrol as a preventive agent against the growth of t(4;11) acute lymphoblastic leukemia (ALL) was evaluated in NOD.CB17-Prkdcscid/J mice engrafted with the human t(4;11) ALL SEM cell line.
Ducore, Jonathan M, Keen, Carl L, Newman, John W, Pedersen, Theresa L, Storms, David H, Zunino, Susan J   +5 more
core   +1 more source