Results 131 to 140 of about 1,001 (167)
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Characterization of human arylsulfatase a glycans
International Journal of Biochemistry, 1994Despite numerous studies on arylsulfatase A, the structure of the glycans present in each of its two subunits has not been determined. This is important because the carbohydrate component of human arylsulfatase A synthesized in tumor tissues and transformed cells has been shown to undergo apparent changes.
Bogusław Wójczyk +3 more
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Pseudodeficiency of arylsulfatase A: a counseling dilemma
Clinical Genetics, 1987Arylsulfatase A (ASA) deficiency is the cause of early and late onset metachromatic leukodystrophy (MLD). Low ASA levels are detected in some healthy individuals who are pseudodefi‐cient (PD). PD individuals can be distinguished, because PD fibroblasts hydrolyze14C‐sulfatide at similar rates to normal fibroblasts.
D. A. Wenger +2 more
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Arylsulfatase Activity of Soils
Soil Science Society of America Journal, 1970AbstractThe detection of arylsulfatases (enzymes that hydrolyze aryl sulfates) in soils is reported, and a simple method of assaying soil arylsulfatase activity is described. This method involves colorimetric estimation of the p‐nitrophenol released by arylsulfatase activity when soil is incubated with buffered (pH 5.8) potassium p‐nitrophenyl sulfate ...
M. A. Tabatabai, J. M. Bremner
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A simple chromogenic assay for arylsulfatase A
Clinica Chimica Acta, 1987Arylsulfatase A hydrolyzes the artificial chromogenic substrate 4-nitrocatechol-sulfate at 0 degree C at a rate of 24% of that at 37 degrees C whereas arylsulfatase B is almost inactive at 0 degree C. Based on this observation, a simple assay was developed which permits the accurate determination of low residual arylsulfatase A activities in cultured ...
Ernst Conzelmann, Mary Lee-Vaupel
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Specific determination of arylsulfatase A activity
Experientia, 1986Arylsulfatase activities in biological materials are too low to be detected by the methods available hitherto. A sensitive and specific assay method for arylsulfatase A (AS-A) has been developed in the present study. Ascorbate-2-sulfate is known to be a specific natural substrate of AS-A; the ascorbic acid liberated by the action of AS-A was ...
Y. Seyama, H. Inoue, S. Yamashita
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Arylsulfatase A Pseudodeficiency - Incidence in Poland
European Journal of Human Genetics, 1996Arylsulfatase A (ASA) pseudodeficiency (Pd) was defined as the in vitro measurement of low enzyme activity in a healthy person. A variable incidence of the Pd allele was found in different populations; it was 10-20 times higher than that of metachromatic leukodystrophy (MLD).
Barbara Czartoryska +3 more
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Pseudodeficiencies of Arylsulfatase A and Galactocerebrosidase Activities
Developmental Neuroscience, 1991Pseudodeficiency is defined as the in vitro measurement of low activity (usually under 15% of the normal mean for controls) of an enzyme in a healthy person. They may be hard to distinguish from presymptomatic people who will present with adult-onset clinical disease.
E Louie, D A Wenger
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Arylsulfatase A Variants in Patients with Alcoholism
Alcoholism: Clinical and Experimental Research, 1984Leukocytes from 200 mentally ill patients and 100 normal controls were analyzed for eiectrophoretic variants of arylsulfatase A. Four different variant forms were found in 15 subjects. There is a relatively high occurrence of the arylsulfatase A variants in patients with alcoholism. Twenty‐one per cent (12/56) of patients with alcoholism have a variant
Atul R. Hulyalkar +2 more
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Arylsulfatase in coelomocytes ofHolothuria polii
Experientia, 1988Holothuria polii coelomocytes possess arylsulfatase enzymes. Two pH optima were found for arylsulfatase activity in cell lysate preparations, one at pH 5.0 and the other at pH 5.8. Both increased after injection of zymosan particles or formalinized sheep red blood cells (fSR-BC), indicating an active role of the enzymes during phagocytosis of ...
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Arylsulfatases of human tissue studies on a form of arylsulfatase B found predominantly in brain
Biochimica et Biophysica Acta (BBA) - Enzymology, 1977The distribution of soluble arylsulfatase (aryl-sulfate sulfohydrolases, EC 3.1.6.1) in human tissues was investigated by DEAE-cellulose chromatography, All tissues examined contained arylsulfatase A and arylsulfatase B. In addition, brain singularly contained significant quantities (15-25% of total arylsulfatase) of a minor anionic arylsulfatase from ...
Audrey R. Killgrove +3 more
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