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Pleural mesothelioma and lung cancer risks in relation to occupational history and asbestos lung burden. [PDF]
Occupational and Environmental Medicine, 2015 BACKGROUND: We have conducted a population-based study of pleural mesothelioma patients with occupational histories and measured asbestos lung burdens in occupationally exposed workers and in the general population.
Burdett, G +9 more
core +3 more sources
Elemental analysis of histological specimens: A method to unmask nano asbestos fibers [PDF]
European Journal of Histochemistry, 2016 There is recent mounting evidence that nanoparticles may have enhanced toxicological potential in comparison to the same material in the bulk form. The aim of this study was to develop a new method for unmask asbestos nanofibers from Formalin-Fixed ...
Anemona, L +6 more
core +3 more sources
Translational Lung Cancer Research, 2020 Research has established a strong association between asbestos exposure and malignant mesothelioma, a deadly form of cancer. Since the early 1980’s many countries have restricted or banned the production of asbestos, leading to a decline of occupational ...
N. Alpert +2 more
semanticscholar +1 more source
Must countries shoulder the burden of mesothelioma to ban asbestos? A global assessment
BMJ Global Health, 2022 Introduction Mesothelioma is a key asbestos-related disease (ARD) but can be difficult to diagnose. Countries presumably ban asbestos to reduce future ARD burdens, but it is unknown if countries ban asbestos as a consequence of ARD burdens.
Seong-Kyu Kang +10 more
doaj +1 more source
Nature Communications, 2022 Immune checkpoint blockade (ICB) is partially successful as a cancer therapy. Here using mouse models, the authors transcriptionally monitor responding and non-responding tumours showing that responding tumours were associated with transient IFN-β ...
Rachael M. Zemek +15 more
doaj +1 more source
Asbestos induces mesothelial cell transformation via HMGB1-driven autophagy
Proceedings of the National Academy of Sciences of the United States of America, 2020 Significance Millions of people have been exposed to asbestos and are at increased risk of developing mesothelioma, an aggressive malignancy resistant to current therapies.
Jiaming Xue +18 more
semanticscholar +1 more source
How asbestos and other fibers cause mesothelioma
Translational Lung Cancer Research, 2020 Mesothelioma has long been associated with the exposure to asbestos, which was largely used in manufacturing activities. Toxicology studies in vitro and in vivo demonstrated that asbestos fibers were carcinogenic, and epidemiology studies revealed that ...
G. Gaudino, Jiaming Xue, Haining Yang
semanticscholar +1 more source
Remote Sensing, 2020 Due to the pathogenic nature of asbestos, a statutory ban on asbestos-containing products has been in place in Poland since 1997. In order to protect human health and the environment, it is crucial to estimate the quantity of asbestos–cement products in ...
M. Krówczyńska +3 more
semanticscholar +1 more source
Asbestos-related cancers: the ‘Hidden Killer’ remains a global threat
Expert Review of Anticancer Therapy, 2020 Introduction: Asbestos, the most frequent cause of occupational cancer, continues to be consumed on a massive scale, with millions of people exposed on a daily basis.
N. van Zandwijk, G. Reid, A. Frank
semanticscholar +1 more source
BMC Research Notes, 2017 Objective MicroRNAs are frequently downregulated in cancer, and restoring expression has tumour suppressive activity in tumour cells. Our recent phase I clinical trial investigated microRNA-based therapy in patients with malignant pleural mesothelioma ...
Patrick Winata +5 more
doaj +1 more source