Results 91 to 100 of about 191,294 (329)

Asbestos Induces Oxidative Stress and Activation of Nrf2 Signaling in Murine Macrophages: Chemopreventive Role of the Synthetic Lignan Secoisolariciresinol Diglucoside (LGM2605)

International Journal of Molecular Sciences, 2016
The interaction of asbestos fibers with macrophages generates harmful reactive oxygen species (ROS) and subsequent oxidative cell damage that are key processes linked to malignancy.
R. Pietrofesa, Anastasia Velalopoulou, S. Albelda, M. Christofidou-Solomidou   +3 more
semanticscholar   +1 more source

Carillion's Fall: Accounting for Construction Projects*

Accounting Perspectives, EarlyView.
ABSTRACT This case describes the circumstances surrounding the fall of Carillion plc, a large UK construction company. Carillion issued a series of write‐downs that hurt investor confidence and led to debt covenant violations. Students assume the role of a fictional investor, Holly Chapman, who has lost money investing in Carillion.
Mary Gillett, Darren Henderson, Pooja Krishen   +2 more
wiley   +1 more source

A case of laryngeal cancer induced by exposure to asbestos in a construction site supervisor [PDF]

, 2016
Background: Construction site supervisors are exposed to many chemicals, dusts, and metals including asbestos. Asbestos is a hazardous chemical that is carcinogenic. Laryngeal cancer is not a rare disease in Korea.
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core   +2 more sources

Cost–benefit analysis of landfill emergency securing: Two applications in Southern Italy

Annals of Public and Cooperative Economics, EarlyView.
Abstract The systematic use of landfills as a method of waste disposal is leaving a heavy legacy in terms of environmental pollution, especially in the case of illegal or non‐compliant disposal sites. When no environmental precaution is adopted, harmful substances' release imposes relevant health risk to the surrounding population.
Nicola Comincioli, Ilenia Gaia Romani, Sergio Vergalli   +2 more
wiley   +1 more source

Mapping Asbestos-Cement Roofing with Hyperspectral Remote Sensing over a Large Mountain Region of the Italian Western Alps [PDF]

, 2014
The World Health Organization estimates that 100 thousand people in the world die every year from asbestos-related cancers and more than 300 thousand European citizens are expected to die from asbestos-related mesothelioma by 2030.
A. Marchesi, C. Albonico, F. Frassy, F. Rota Nodari, G. Candiani, G. Dalla Via, M. Gianinetto, M. Rusmini, P. Maianti   +8 more
core   +2 more sources

Asbestos Ban in Italy: A Major Milestone, Not the Final Cut

International Journal of Environmental Research and Public Health, 2017
Background and history: Italy was the main asbestos producer and one of the greatest consumers in 20th century Europe until the asbestos ban was introduced in 1992. Asbestos exposure affected the population in a wide range of working environments, namely
D. Marsili, A. Angelini, C. Bruno, M. Corfiati, A. Marinaccio, S. Silvestri, A. Zona, P. Comba   +7 more
semanticscholar   +1 more source

KEYNOTE‐A17: First‐Line Pembrolizumab Plus Cisplatin–Pemetrexed in Japanese Participants With Advanced Pleural Mesothelioma

Cancer Science, EarlyView.
In the phase 1b KEYNOTE‐A17 study of first‐line pembrolizumab plus chemotherapy in Japanese participants with advanced pleural mesothelioma (PM), 2 of 18 participants (11%) evaluated experienced dose‐limiting toxicities. The objective response rate among all 19 participants in the study was 74%, with 14 participants achieving a partial response and a ...
Takashi Kijima, Terufumi Kato, Yasushi Goto, Kozo Kuribayashi, Koji Mikami, Yoshiki Negi, Shuji Murakami, Tatsuya Yoshida, Masae Homma, Akira Wakana, Kazuo Noguchi, Nobukazu Fujimoto   +11 more
wiley   +1 more source

A combination of PD-1 and TIGIT immune checkpoint inhibitors elicits a strong anti-tumour response in mesothelioma

Journal of Experimental & Clinical Cancer Research
Background Finding effective and curative treatment for mesothelioma remains challenging. While the introduction of immunotherapy combinations using ipilimumab (anti-CTLA-4) and nivolumab (anti-PD-1) have offered hope for some patients, a large ...
Huaikai Shi, Ta-Kun Yu, Ben Johnson, Sakthi Priya Selvamani, Ling Zhuang, Kenneth Lee, Sonja Klebe, Samuel Smith, Kirby Wong, Kate Chen, Georgina Clark, Emma M. Rath, Holly Pearson, David Gallego Ortega, Anthony Linton, Steven Kao, Pablo Silveira, Yuen Yee Cheng   +17 more
doaj   +1 more source

Asbestos Lessons: The Consequences of Asbestos Litigation [PDF]

, 2007
not ...
Carrington, Paul D.
core   +1 more source

PBK Expression Promotes the Aggressive Phenotypes of Mesothelioma

Cancer Science, EarlyView.
PBK plays a crucial role in cell survival in mesothelioma and is associated with worse outcome. PBK is a promising therapeutic target that may serve as a prognostic biomarker, enabling personalized treatment of mesothelioma. ABSTRACT Mesothelioma is one of the most aggressive neoplasms worldwide that has a particularly poor prognosis.
Kazumi Hori, Ichidai Tanaka, Tatsuhiro Sato, Mika Sato, Yuta Kodama, Hideyuki Itoigawa, Yuichi Abe, Taketo Kato, Ayumu Taguchi, Mitsuo Sato, Yoshitaka Sekido, Toyofumi Fengshi Chen‐Yoshikawa, Makoto Ishii   +12 more
wiley   +1 more source