Results 11 to 20 of about 163,003 (272)

Pleural mesothelioma and lung cancer risks in relation to occupational history and asbestos lung burden. [PDF]

, 2015
BACKGROUND: We have conducted a population-based study of pleural mesothelioma patients with occupational histories and measured asbestos lung burdens in occupationally exposed workers and in the general population.
Burdett, G, Carpenter, J, Darnton, A, Davison, L, Franchini, A, Gilham, C, Hodgson, J, Nicholson, AG, Peto, J, Rake, C   +9 more
core   +2 more sources

A link between the fibroblast growth factor axis and the miR‐16 family reveals potential new treatment combinations in mesothelioma

Molecular Oncology, 2018
Malignant pleural mesothelioma (MPM) is an aggressive malignancy with very limited therapeutic options. Fibroblast growth factor (FGF) signals play important roles in mesothelioma cell growth.
Karin Schelch, Michaela B. Kirschner, Marissa Williams, Yuen Y. Cheng, Nico vanZandwijk, Michael Grusch, Glen Reid   +6 more
doaj   +1 more source

A systematic investigation of the maximum tolerated dose of cytotoxic chemotherapy with and without supportive care in mice

BMC Cancer, 2017
Background Cytotoxic chemotherapeutics form the cornerstone of systemic treatment of many cancers. Patients are dosed at maximum tolerated dose (MTD), which is carefully determined in phase I studies.
Wayne J. Aston, Danika E. Hope, Anna K. Nowak, Bruce W. Robinson, Richard A. Lake, W. Joost Lesterhuis   +5 more
doaj   +1 more source

Surface reactivity of amphibole asbestos. A comparison between crocidolite and tremolite [PDF]

, 2017
Among asbestos minerals, fibrous riebeckite (crocidolite) and tremolite share the amphibole structure but largely differ in terms of their iron content and oxidation state. In asbestos toxicology, iron-generated free radicals are largely held as one of
Andreozzi, Giovanni B., Corazzari, Ingrid, Pacella, Alessandro, Tomatis, Maura, Turci, Francesco   +4 more
core   +3 more sources

Hemolysis and its impact on cell-free microRNA biomarkers

Frontiers in Genetics, 2013
Cell-free microRNAs in plasma and serum have become a promising source of biomarkers for various diseases. Despite rapid progress in this field, there remains a lack of consensus regarding optimal quantification methods, reference genes and quality ...
Michaela B Kirschner, J James B Edelman, J James B Edelman, Steven Chuan-Hao Kao, Michael P Vallely, Michael P Vallely, Nico eVan Zandwijk, Glen eReid   +7 more
doaj   +1 more source

A postmortem case control study of asbestos burden in lungs of malignant mesothelioma cases

Journal of Translational Medicine, 2023
Background Asbestos lung content is regarded as the most reliable tool for causal attribution of malignant mesothelioma (MM) to previous asbestos exposures. However, there is a lack of studies on asbestos burden in lungs of MM patients in comparison with
S. D. Visonà, B. Bertoglio, C. Favaron, S. Capella, E. Belluso, C. Colosio, S. Villani, T. Ivic-Pavlicic, E. Taioli   +8 more
doaj   +1 more source

The Use of Geopolymers for the Disposal of Asbestos-containing Materials [PDF]

MATEC Web of Conferences, 2020
Asbestos is widely known as a hazardous material and can contribute to many diseases. Its removal and neutralization are complicated, it requires proper preparation and the use of appropriate technology.
Łach Michał, Lichocka Katarzyna, Hebdowska-Krupa Maria, Lin Wei-Ting, Korniejenko Kinga   +4 more
doaj   +1 more source

Ongoing downplaying of the carcinogenicity of chrysotile asbestos by vested interests

Journal of Occupational Medicine and Toxicology, 2021
Industries that mine, manufacture and sell asbestos or asbestos-containing products have a long tradition of promoting the use of asbestos, while placing the burden of economic and health costs on workers and society.
Xaver Baur, Arthur L. Frank
doaj   +1 more source

Diagnostic limitations of lung fiber counts in asbestos-related diseases

The Journal of Scientific Practice and Integrity, 2023
# Background Lung dust fibre analyses have been used by some pathologists to estimate past asbestos exposure in the workplace and its related health risks.
Joachim Schneider, Rolf Arhelger, Bernd Brückel, Xaver Baur   +3 more
doaj   +1 more source

Tumour associated lymphocytes in the pleural effusions of patients with mesothelioma express high levels of inhibitory receptors

BMC Research Notes, 2018
Objective Pleural effusion (PE) is a common feature of malignant pleural mesothelioma. These effusions typically contain lymphocytes and malignant cells. We postulated that the PE would be a source of lymphocytes for analysis of tumor immune milieu.
Jonathan Chee, Mark W. Watson, Abha Chopra, Bella Nguyen, Alistair M. Cook, Jenette Creaney, Willem J. Lesterhuis, Bruce W. Robinson, Y. C. Gary Lee, Anna K. Nowak, Richard A. Lake, Alison M. McDonnell   +11 more
doaj   +1 more source