Results 21 to 30 of about 191,294 (329)

A postmortem case control study of asbestos burden in lungs of malignant mesothelioma cases

Journal of Translational Medicine, 2023
Background Asbestos lung content is regarded as the most reliable tool for causal attribution of malignant mesothelioma (MM) to previous asbestos exposures. However, there is a lack of studies on asbestos burden in lungs of MM patients in comparison with
S. D. Visonà, B. Bertoglio, C. Favaron, S. Capella, E. Belluso, C. Colosio, S. Villani, T. Ivic-Pavlicic, E. Taioli   +8 more
doaj   +1 more source

A link between the fibroblast growth factor axis and the miR‐16 family reveals potential new treatment combinations in mesothelioma

Molecular Oncology, 2018
Malignant pleural mesothelioma (MPM) is an aggressive malignancy with very limited therapeutic options. Fibroblast growth factor (FGF) signals play important roles in mesothelioma cell growth.
Karin Schelch, Michaela B. Kirschner, Marissa Williams, Yuen Y. Cheng, Nico vanZandwijk, Michael Grusch, Glen Reid   +6 more
doaj   +1 more source

A systematic investigation of the maximum tolerated dose of cytotoxic chemotherapy with and without supportive care in mice

BMC Cancer, 2017
Background Cytotoxic chemotherapeutics form the cornerstone of systemic treatment of many cancers. Patients are dosed at maximum tolerated dose (MTD), which is carefully determined in phase I studies.
Wayne J. Aston, Danika E. Hope, Anna K. Nowak, Bruce W. Robinson, Richard A. Lake, W. Joost Lesterhuis   +5 more
doaj   +1 more source

Hemolysis and its impact on cell-free microRNA biomarkers

Frontiers in Genetics, 2013
Cell-free microRNAs in plasma and serum have become a promising source of biomarkers for various diseases. Despite rapid progress in this field, there remains a lack of consensus regarding optimal quantification methods, reference genes and quality ...
Michaela B Kirschner, J James B Edelman, J James B Edelman, Steven Chuan-Hao Kao, Michael P Vallely, Michael P Vallely, Nico eVan Zandwijk, Glen eReid   +7 more
doaj   +1 more source

Comprehensive Testing of Chemotherapy and Immune Checkpoint Blockade in Preclinical Cancer Models Identifies Additive Combinations

Frontiers in Immunology, 2022
Antibodies that target immune checkpoints such as cytotoxic T lymphocyte antigen 4 (CTLA‐4) and the programmed cell death protein 1/ligand 1 (PD-1/PD-L1) are now a treatment option for multiple cancer types. However, as a monotherapy, objective responses
Nicola Principe, Nicola Principe, Nicola Principe, Wayne J. Aston, Danika E. Hope, Caitlin M. Tilsed, Caitlin M. Tilsed, Caitlin M. Tilsed, Scott A. Fisher, Scott A. Fisher, Scott A. Fisher, Louis Boon, Ian M. Dick, Ian M. Dick, Wee Loong Chin, Wee Loong Chin, Wee Loong Chin, Alison M. McDonnell, Anna K. Nowak, Anna K. Nowak, Anna K. Nowak, Richard A. Lake, Richard A. Lake, Richard A. Lake, Jonathan Chee, Jonathan Chee, Jonathan Chee, Willem Joost Lesterhuis, Willem Joost Lesterhuis, Willem Joost Lesterhuis, Willem Joost Lesterhuis   +30 more
doaj   +1 more source

Cumulative asbestos exposure and mortality from asbestos related diseases in a pooled analysis of 21 asbestos cement cohorts in Italy

Environmental Health, 2019
BackgroundDespite the available information on cancer risk, asbestos is used in large areas in the world, mostly in the production of asbestos cement.
F. Luberto, D. Ferrante, S. Silvestri, A. Angelini, F. Cuccaro, A. Nannavecchia, E. Oddone, M. Vicentini, F. Barone-Adesi, T. Cena, D. Mirabelli, L. Mangone, F. Roncaglia, O. Sala, S. Menegozzo, R. Pirastu, D. Azzolina, S. Tunesi, E. Chellini, L. Miligi, Patrizia Perticaroli, A. Pettinari, V. Bressan, E. Merler, P. Girardi, L. Bisceglia, A. Marinaccio, S. Massari, C. Magnani, Lisa Antonio Carol Barbara Stefania Manuela Giuseppe Pa Bauleo Baldassarre Brentisci Cortini Curti Gangemi, L. Bauleo, A. Baldassarre, C. Brentisci, Barbara Cortini, S. Curti, Manuela Gangemi, G. Gorini, Patrizia Legittimo, F. Marinelli, P. Marinilli, S. Mattioli, M. Musti, C. Panato, V. Pavone, A. Ranucci, E. Romeo, C. Scarnato, C. Storchi, A. Stura, Simona Verdi   +49 more
semanticscholar   +1 more source

Asbestos in Talc [PDF]

Environmental Health Perspectives, 1974
Talc deposits include asbestos minerals such as chrysotile and amphiboles that may be carried over into consumer products. Optical microscopy and x-ray diffraction analyses may not reveal their presence. Examples are given of electron microscopy procedures that permit detection and measurement.
openaire   +3 more sources

Mongolia: Failure of Total Banning of Asbestos

Annals of Global Health, 2023
The primary uses of asbestos in Mongolia are in thermal power plants, construction and at railway companies. There is, however, limited data on both asbestos consumption and asbestos related disease (ARD) in Mongolia.
Naransukh Damiran, Arthur L. Frank
doaj   +1 more source

Surface reactivity of amphibole asbestos. A comparison between crocidolite and tremolite [PDF]

, 2017
Among asbestos minerals, fibrous riebeckite (crocidolite) and tremolite share the amphibole structure but largely differ in terms of their iron content and oxidation state. In asbestos toxicology, iron-generated free radicals are largely held as one of
Andreozzi, Giovanni B., Corazzari, Ingrid, Pacella, Alessandro, Tomatis, Maura, Turci, Francesco   +4 more
core   +3 more sources

Environmental asbestos exposure and risk of mesothelioma.

Annals of Translational Medicine, 2017
Mesothelioma is commonly considered an occupational disease occurring as a result of asbestos exposure in the workplace. Several avenues for environmental asbestos exposures have been described and may be associated with asbestos related disease ...
C. Noonan
semanticscholar   +1 more source