Results 101 to 110 of about 263,599 (283)

Liquid-based cytology - new possibilities in the diagnosis of cervical lesions [Tekuća citologija - nove mogućnosti u dijagnostici lezija vrata maternice] [PDF]

open access: yes, 2010
Liquid-based cytology (LBC) enables the use of supplementary methods in the diagnosis and prognosis of cervical lesions. The aim of this study was to analyze the correlation between p16INK4a immunoexpression in ThinPrep cervical cytologic samples and ...
Babić, Damir   +10 more
core  

Extracellular Vesicles in Autoimmune Diseases: From Diagnostic Biomarkers to Engineered Therapeutics

open access: yesAdvanced Science, EarlyView.
This review provides a systematic comparison of extracellular vesicles (EVs) from both mammalian and plant sources in the context of autoimmune diseases. It highlights their emerging roles as precision biomarkers and engineered therapeutic platforms.
Yufei Wu   +6 more
wiley   +1 more source

Artesunate Ameliorates APAP‐induced Liver Injury by Promoting NEDD4L‐Mediated Ubiquitination and Degradation of TXNIP

open access: yesAdvanced Science, EarlyView.
ABSTRACT Liver injury can lead to severe acute liver failure and even death in patients. Artesunate (ART), which is a derivative of artemisinin that has been approved by the FDA for the treatment of malaria, has significant regulatory effects on cell death and inflammation.
Zhe Zhang   +17 more
wiley   +1 more source

Inhibitory Effects of Ethanol on the NLRP3 Inflammasome [PDF]

open access: yes, 2015
Immunosuppression is a major complication of alcoholism and contributes to increased rates of opportunistic infections and sepsis associated with the addiction.
Hoyt, Laura Rose
core   +1 more source

Polydopamine‐Encapsulated Probiotics Restore Gut Homeostasis and Reinstate Macrophage Efferocytosis in Systemic Lupus Erythematosus

open access: yesAdvanced Science, EarlyView.
Polydopamine‐encapsulated probiotics restore gut homeostasis and reinstate macrophage efferocytosis, thereby reestablishing immune tolerance and mitigating systemic autoimmunity, highlighting a bioengineered microbiota‐based therapeutic strategy for SLE.
Ruimiao Wu   +10 more
wiley   +1 more source

Enhancing Safety-Critical Brake System Testing with Vector SIL over Complex Vector HIL

open access: yesEngineering Proceedings
Advanced vehicle technologies that substitute or assist the driver are crucial and safety-critical elements, including independently acting electronic control units.
János Májer   +4 more
doaj   +1 more source

18β‐Glycyrrhetinic Acid and a Nano‐Liposomal Formulation Alleviate Depression‐Like Behaviors via the Microglial mTOR‐Autophagy‐NLRP3 Axis

open access: yesAdvanced Science, EarlyView.
Using a novel zebrafish‐based inflammatory screening strategy, we screened and identified 18β‐glycyrrhetinic acid (18β‐GA) as a promising anti‐inflammatory candidate. We uncover a microglial mTOR–autophagy–NLRP3 axis that constitutes the mechanistic core of 18β‐GA–mediated neuroprotection.
Hua Gan   +11 more
wiley   +1 more source

THE DAILY 110 MHZ RADIO WAVE SKY SURVEY: STATISTICAL ANALYSIS OF IMPULSE PHENOMENA FROM OBSERVATION IN 2012-2013

open access: yesOdessa Astronomical Publications, 2016
On the Pushchino Radio Astronomy Observatory of Lebedev Physical Institute by radio telescope BSA (Big Scanning Antenna) in 2012 started daily multi-beam observations at the frequency range 109- 112 MHz.
V. A. Samodurov   +6 more
doaj   +1 more source

Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance

open access: yesAdvanced Science, EarlyView.
DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin   +15 more
wiley   +1 more source

SubSpectralNet - Using Sub-Spectrogram based Convolutional Neural Networks for Acoustic Scene Classification

open access: yes, 2019
Acoustic Scene Classification (ASC) is one of the core research problems in the field of Computational Sound Scene Analysis. In this work, we present SubSpectralNet, a novel model which captures discriminative features by incorporating frequency band ...
Benetos, Emmanouil   +2 more
core   +1 more source

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