Results 181 to 190 of about 263,599 (283)

Proteomics‐Based Identification of the Pyroptosis‐Related Biomarker PCSK9 and Its Association With the Pathogenesis of Rheumatoid Arthritis

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Rheumatoid arthritis (RA) is a common autoimmune disease, and early diagnosis is critical for effective treatment. This study aims to identify potential biomarkers related to pyroptosis through serum proteomics analysis, offering new insights for the early diagnosis of RA.
Lei Wang   +10 more
wiley   +1 more source

RBMX Transcriptionally Repressed by EZH2‐Associated H3K27me3 Modification Attenuates Pyroptosis in Renal Ischemia/Reperfusion Injury via Regulating SIRT3/NLRP3 Inflammasome Activation

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Ischemic reperfusion injury (IRI) to kidney is a significant clinical factor in acute kidney injury (AKI). This study aimed to investigate the new role of RNA‐binding motif protein X‐linked (RBMX), a modulator of m6A methylation, in renal IRI and to examine the associated regulatory mechanisms. An in vitro renal IRI model was established using
Yi‐Han Wang   +4 more
wiley   +1 more source

Optical Coherence Tomography as an Emerging Technique for Identifying Pediatric Middle Ear Effusion

open access: yesThe Laryngoscope, EarlyView.
This prospective study evaluated optical coherence tomography (OCT) as a diagnostic tool for identifying middle ear effusion (MEE) in 164 pediatric patients. OCT was determined to have a sensitivity of 74% and a specificity of 93%, comparable to otoscopy and tympanometry, with moderate agreement (κ = 0.41) between clinical and non‐clinical raters.
Roger Neuberger   +7 more
wiley   +1 more source

Circadian Immunity and Vascular Inflammation in Cardiovascular Disease Chronotherapy Windows: Time for a Re‐Assessment

open access: yesMed Research, EarlyView.
ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang   +22 more
wiley   +1 more source

Antihyperglycemic and antioxidant potential of <i>Curcuma caesia</i> in mitigating oxidative stress and tissue damage in mice with STZ-induced diabetes. [PDF]

open access: yesAnn Med Surg (Lond)
Lyngdoh AR   +10 more
europepmc   +1 more source

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