Results 21 to 30 of about 44,226 (247)

Characterization of the β-tubulin gene family in Ascaris lumbricoides and Ascaris suum and its implication for the molecular detection of benzimidazole resistance

PLoS Neglected Tropical Diseases, 2021
Background The treatment coverage of control programs providing benzimidazole (BZ) drugs to eliminate the morbidity caused by soil-transmitted helminths (STHs) is unprecedently high.
Sara Roose, Russell W. Avramenko, Stephen M. J. Pollo, J. Wasmuth, S. Ame, Mio Ayana, M. Betson, P. Cools, D. Dana, Ben P. Jones, Z. Mekonnen, Arianna Morosetti, Abhinaya Venkatesan, J. Vlaminck, M. Workentine, B. Levecke, J. Gilleard, P. Geldhof   +17 more
semanticscholar   +1 more source

Testing sand and soil from selected playgrounds in Lublin for eggs of nematodes of the genus: Ascaris, Toxocara, Trichuris

Current Issues in Pharmacy and Medical Sciences, 2022
Children need to play outdoors. It is a natural tendency for young children to put everything in their mouths. Hygienic condition of playgrounds is important for maintaining their health.
Chodun-Wroblewska Wiktoria, Nieradko-Iwanicka Barbara, Iwanicki Janusz Andrzej   +2 more
doaj   +1 more source

Non-potable water reuse and the public health risks from protozoa and helminths: a case study from a city with a semi-arid climate

Journal of Water and Health, 2023
The study estimated the risk due to Cryptosporidium, Giardia, and Ascaris, associated with non-potable water reuse in the city of Jaipur, India. The study first determined the exposure dose of Cryptosporidium, Giardia, and Ascaris based on various ...
Ayushi Chaudhary, Shubham Rana, Rajveer Singh, Patrick L. Gurian, Walter Betancourt, Arun Kumar, Amit Kumar   +6 more
doaj   +1 more source

Transient Ascaris suum larval migration induces intractable chronic pulmonary disease and anemia in mice

PLoS Neglected Tropical Diseases, 2021
Ascariasis is one of the most common infections in the world and associated with significant global morbidity. Ascaris larval migration through the host’s lungs is essential for larval development but leads to an exaggerated type-2 host immune response ...
Yifan Wu, Evan Li, Morgan J. Knight, Grace O. Adeniyi-Ipadeola, Lijun Song, A. Burns, A. C. Gazzinelli-Guimarães, R. Fujiwara, M. Bottazzi, J. Weatherhead   +9 more
semanticscholar   +1 more source

Intestinal Parasites of Zoonotic Significance in Human and Domestic Animals in a Rural Setting in Nepal. [PDF]

Vet Med Sci
Intestinal parasites are shared among humans and domestic animals. Rural setting is critical to enhance parasite zoonosis in Nepal. ABSTRACT Intestinal parasitic (IP) species with zoonotic significance are major public health issues, mostly prevalent in developing countries, leading to high morbidity and mortality. The present study aimed to assess the
Rai P, Ghimire TR.
europepmc   +2 more sources

The long and winding road of Ascaris larval migration: the role of mouse models

Parasitology, 2021
Abstract Ascaris lumbricoides and Ascaris suum are helminth parasites of humans and pigs, respectively. The life cycle of Ascaris sets it apart from the other soil-transmitted helminths because of its hepato-tracheal migration.
C. Holland
semanticscholar   +1 more source

Microbial pollution in inland recreational freshwaters of Quetta, Pakistan: an initial report

Journal of Water and Health, 2022
Parasitic contamination of surface waters, especially recreational waters, is a serious problem for under-developed nations like Pakistan, where numerous outbreaks of parasitic diseases are reported each year.
Muhammad Luqman, Muhammad Umer Farooq Awan, Sohaib Muhammad, Shakeela Daud, Asma Yousafzai, Fariha Arooj   +5 more
doaj   +1 more source

Identification of key interactions of benzimidazole resistance-associated amino acid mutations in Ascaris β-tubulins by molecular docking simulations

Scientific Reports, 2021
Ascaris species are soil-transmitted helminths that infect humans and livestock mainly in low and middle-income countries. Benzimidazole (BZ) class drugs have predominated for many years in the treatment of Ascaris infections, but persistent use of BZs ...
Ben P. Jones, A. H. V. van Vliet, E. J. LaCourse, M. Betson   +3 more
semanticscholar   +1 more source

A historical and systematic overview of Ascaris vaccine development

Parasitology, 2021
Abstract Ascariasis is the most prevalent helminth infection in the world and leads to significant, life-long morbidity, particularly in young children. Current efforts to control and eradicate ascariasis in endemic regions have been met with significant
A. C. Gazzinelli-Guimarães, P. Gazzinelli-Guimarães, J. Weatherhead   +2 more
semanticscholar   +1 more source

Molecular evidence of hybridization between pig and human Ascaris indicates an interbred species complex infecting humans

eLife, 2020
Human ascariasis is a major neglected tropical disease caused by the nematode Ascaris lumbricoides. We report a 296 megabase (Mb) reference-quality genome comprised of 17,902 protein-coding genes derived from a single, representative Ascaris worm.
Alice V. Easton, Shenghan Gao, S. Lawton, S. Bennuru, A. Khan, Eric Dahlstrom, Rita G. Oliveira, Stella Kepha, S. Porcella, J. Webster, R. Anderson, M. Grigg, Richard E. Davis, Jianbin Wang, T. Nutman   +14 more
semanticscholar   +1 more source