Halorotetin B, A Novel Terpenoid Compound Derived from Marine Ascidian, Suppresses Tumor Growth by Targeting the Cell Cycle Regulator UBE2C. [PDF]
Halorotetin B, a novel small‐molecule terpenoid identified from an edible marine ascidian, exhibits strong anti‐tumor activity both in vitro and in vivo through direct targeting UBE2C to induce tumor cell cycle arrest and then lead tumor cell senescence. As a newly discovered UBE2C inhibitor, Halorotetin B can serve as a novel potential cell senescence
Han S +6 more
europepmc +2 more sources
Recombinant Proteins: A Molecular Tool to Understand Marine Adhesion and to Advance Biomaterials. [PDF]
The production of recombinant proteins represents a fundamental step in the characterisation of marine invertebrate adhesives and in the development of bio‐inspired glues. The association of these proteins with other components such as ions, proteins, polysaccharides, or polymers enables the fabrication of biomaterials for various healthcare ...
Whaite A +4 more
europepmc +2 more sources
The tandem-random transition of cellular patterning: proposed roles of N-cadherin-based orientational cell adhesions in the development, maintenance, and degeneration of the nucleus pulposus. [PDF]
ABSTRACT Intervertebral disc degeneration (IDD) can contribute to lower back and neck pain. In IDD, the most affected component of the intervertebral disc is the nucleus pulposus (NP). Derived from the notochord, where cells are organized into a tandem configuration, young NP cells cluster in three‐dimensional (3D) networks embedded in a gelatinous ...
Wei X, Vo N, Sowa GA.
europepmc +2 more sources
Ascidians are considered as filter-feeder biofouling pests that negatively affect aquaculture facilities. However, they can also be recognized as a potential co-cultured/extractive species for integrated multi-trophic aquaculture (IMTA) with potential ...
Luisa Marques +2 more
doaj +1 more source
Ascidians Outbreak: A Threat For Coral Reefs in Panjang Island, Jepara
Eutrophication and sedimentation have become a major threat to coral reefs in nearby areas with anthropogenic activities. These threats are often accompanied by shifting ecosystems from coral-rich to fast-growing algae-dominated water, and high ...
Dwi Haryanti +4 more
doaj +1 more source
A checklist of halacarid mites (Acari, Halacaridae) found among ascidians (Tunicata, Ascidiacea)
A compilation of marine halacarid mites (Halacaridae) found with ascidians (sea squirts) has been carried out based on published records. In this paper, we listed 19 species found with ascidians, altogether.
Tapas Chatterjee
doaj +1 more source
Impacts of the Establishment of Biofoulants on Greek Aquaculture: Farmers’ Expert Knowledge
Ascidians’ bioaccumulation is frequently responsible for the massive growth of certain species, causing detrimental effects on aquaculture facilities. The goal of this study is to provide, for the first time in the Eastern Mediterranean, information on ...
Dimitrios Tsotsios +4 more
doaj +1 more source
Symbiotic Associations in Ascidians: Relevance for Functional Innovation and Bioactive Potential
Associations between different organisms have been extensively described in terrestrial and marine environments. These associations are involved in roles as diverse as nutrient exchanges, shelter or adaptation to adverse conditions.
Ana Matos, Agostinho Antunes
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Ascidian notochord morphogenesis [PDF]
AbstractThe development of the notochord involves a complex set of cellular behaviors. While these morphogenic behaviors are common to all chordates, the ascidian provides a particularly attractive experimental model because of its relative simplicity. In particular, all notochord morphogenesis in ascidians takes place with only 40 cells, as opposed to
Di, Jiang, William C, Smith
openaire +2 more sources
IDENTIFICATION OF SECONDARY METABOLITE COMPOUNDS IN TUNICATE (Polycarpa aurata) ASSOCIATED BACTERIA
Background: Marine biodiversity in the last few decades has been explored and utilized as marine natural products. The secondary metabolites produced by marine organisms are utilized by humans in various aspects of life.
Sheila Raisa +3 more
doaj +1 more source

