Results 241 to 250 of about 231,898 (315)

Enhancement of immune checkpoint inhibitor efficacy by DHX58+ SELL+ T cells in advanced gastric cancer

VIEW, EarlyView.
We created a coculture system using patient‐derived organoids (PDOs) and tumor‐infiltrating lymphocytes (TILs) that mimics important interactions between PDOs and TILs in the presence of various ICIs. Our findings reveal that CD62L+ T cells, activated by CD44+ cancer stem cells (CSCs), facilitate tumor regression in samples sensitive to ICIs, which is ...
Jie Chen, Youdong Liu, Hongda Pan, Tianyi Cai, Mingde Zang, Xiaowen Liu, Ziwen Long, Xin Fan, Jun Lu, Fenglin Liu   +9 more
wiley   +1 more source

Targeting cancer stem cells predicts response and reverses chemoresistance in ascites-derived ovarian cancer organoids. [PDF]

BMC Med
Zhang X, Zhang W, Cui Y, Zhang Q, Wan D, Li N, Zhang K, Guo H.   +7 more
europepmc   +1 more source

Evaluation of the IOTA ADNEX Model, Two‐Step Strategy and RMI in Routine Gynaecologic Care in Denmark and Implications for Implementation: A Prospective Multicenter Cohort Study

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective To evaluate whether the IOTA ADNEX model and the Two‐Step Strategy improve triage and referral of adnexal masses in routine gynaecologic care compared with the RMI and to identify an appropriate malignancy‐risk threshold. Design Prospective multicenter cohort study. Setting Thirteen non‐tertiary hospitals and clinics and one tertiary
Nikoline Schou Karlsen, Eva Dreisler, Claus Kim Høgdall, Estrid Solyom Høgdall, Mona Aarenstrup Karlsen, Thomas Alexander Gerds, Guðbjörg Andrésdóttir, Lea Langhoff‐Thuesen, Malene Merete Forstholm, Abelone Elisabeth Sakse   +9 more
wiley   +1 more source

Tjalma Syndrome: A Rare Autoimmune Cause of Multisystem Serositis. [PDF]

Cureus
Kodamanchile A, Ekhelikar S, AbiMusaAsa'ari AKA, Aboushehata M, Ahmad N.   +4 more
europepmc   +1 more source

Paediatric renal transplantation: Paediatric surgeons' perspective

Surgical Practice, EarlyView.
Abstract Renal transplantation is the most effective treatment for paediatric end‐stage renal disease (ESRD), offering advantages in survival, growth and neurocognitive development that surpass other renal replacement therapies (RRT). The paediatric setting, however, introduces distinct complexities that distinguish it from adult practice.
Adrian Chi‐heng Fung, Mary Kim Elizabeth Tan Cudia, Ivy Hau‐yee Chan, Kenneth Kak‐yuen Wong   +3 more
wiley   +1 more source

Intraperitoneal administration of NK-92 improves survival in xenografts of early and established ovarian cancer models. [PDF]

PLoS One
Marcus P, Warrington J, Zhang M, Ankathatti-Munegowda M, Wang XH, Rashedi I, Keating A.   +6 more
europepmc   +1 more source

Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia

Journal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer‐related death in children and adolescents. Five‐year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the
Luke R. Holmes, Rishi S. Kotecha, Derek J. Roebuck   +2 more
wiley   +1 more source

Positive ascites cytology in interval debulking surgery predicts poor outcomes of advanced epithelial ovarian cancer achieving complete tumor resection. [PDF]

Sci Rep
Yoshikawa M, Yoshihara M, Emoto R, Matsui S, Kajiyama H.   +4 more
europepmc   +1 more source

Content validation of the new nursing intervention “0565 – ultrasonography: bladder”

International Journal of Nursing Knowledge, EarlyView.
Abstract Purpose To validate the content of the nursing intervention “0565 – ultrasonography: bladder.” Method The content validation study was conducted from September to November 2022, with a sample of 22 specialists who evaluated the components of the nursing intervention “0565 – ultrasonography: bladder,” according to the Nursing Interventions ...
Vítor Monteiro Moraes, Ana Clara de Brito Cruz, Taline Bavaresco, Amália de Fátima Lucena, Cheryl Marie Wagner, Miriam de Abreu Almeida   +5 more
wiley   +1 more source