Results 241 to 250 of about 182,211 (308)

International survey on the management of portal hypertension. [PDF]

Hepatol Commun
Bashiri K, Rabiee A, Northup P, Sarin S, Rockey DC.   +4 more
europepmc   +1 more source

Review Article: Fibrosis Reversal in Metabolic Dysfunction‐Associated Steatohepatitis—The Promise of Emerging Therapeutics

Alimentary Pharmacology &Therapeutics, EarlyView.
Metabolic dysfunction‐associated steatohepatitis is the second commonest US indication for liver transplantation but remains largely undiagnosed and untreated. Fibrosis stage is the strongest predictor of major adverse liver outcomes, with decompensation rates and transplant‐free survival diverging sharply between F3 and F4, while cardiovascular ...
Malek Ayoub, Tsubasa Tsutsumi, Mary E. Rinella   +2 more
wiley   +1 more source

Isolation of extracellular vesicles from minimal volume ascites fluid using strong anion exchange beads. [PDF]

Nanoscale Adv
Cooper TT, Veliz L, Afzali F, Djoumessi C, Hovey OFJ, Myette RL, Johnston TPA, Wells C, Robertson T, Burger D, Abraham SA, Shepherd TG, Craig AW, Lagugné-Labarthet F, Lajoie GA, Postovit LM.   +15 more
europepmc   +1 more source

Pruritus Is Frequent and Persistent and Impacts Quality of Life Among Patients With Primary Sclerosing Cholangitis

Alimentary Pharmacology &Therapeutics, EarlyView.
Among 200 patients with primary sclerosing cholangitis, 38% reported moderate to severe pruritus in the past 6 months. During 6 months of follow up, pruritus severity fluctuated significantly. Pruritus severity was linked to worse colitis activity and lower quality of life.
Richard Dean, Maryam Yazdanfar, Joseph Zepeda, Isha J. Patel, Cynthia Levy, Craig Lammert, Raghav Bordia, Duru Cosar, Katherine Specht, Daniel Pratt, Stuart C. Gordon, Lisa Forman, Fawzy Barry, Michael Li, Usha Gungabissoon, Megan M. McLaughlin, Christopher L. Bowlus   +16 more
wiley   +1 more source

Systemic Therapy for Advanced Hepatocellular Carcinoma with Impaired Liver Function: Navigating the Evidence Gap. [PDF]

Cancers (Basel)
Mohan A, Razumilava N, Abraham H, Anika M, Crysler OV.   +4 more
europepmc   +1 more source

A CECT‐Based 2PI System as a Novel Noninvasive Prognostic Tool for Hepatocellular Carcinoma: A Dual‐Validation Study

Cancer Science, EarlyView.
Using differential weighting, we developed a 2PI‐based risk stratification system for HCC recurrence. A comprehensive prognostic model incorporating clinical variables and the 2PI score further enhanced postoperative prediction in solitary HCC and showed initial generalizability across SR and RFA cohorts.
Yingzhu Cui, Dezhi Zhang, Fan Lin, Liang Guo, Lei Zhang, Kan He, Hongbin Wang, Shuang Zheng, Kun Zhang, Yu Fu, Huimao Zhang   +10 more
wiley   +1 more source

Man with Massively Enlarged Scrotum. [PDF]

J Am Coll Emerg Physicians Open
Lee A, Mateja CF.
europepmc   +1 more source

Retention of a Patency Capsule Shell in a Nonsteroidal Anti‐Inflammatory Drug‐Induced Small‐Bowel Stricture, Detected and Retrieved by Balloon‐Assisted Enteroscopy: Emphasizing the Importance of Confirming Capsule Excretion

Journal of Digestive Diseases, EarlyView.
Shinichiro Kawatoko, Tomohiro Nagasue, Akihiro Shigemori, Akihiro Yoshida, Junji Umeno   +4 more
wiley   +1 more source

Umbilical vein recanalization with a diameter greater than 6.48mm may promote deterioration of liver reserve function: A retrospective cohort study. [PDF]

Medicine (Baltimore)
Ding F, Yang Y, Wang J, Chen L.
europepmc   +1 more source

TOP1MT rs2293925 is an enhancer‐active regulatory SNP that shapes mitochondrial R‐loop dynamics

The FEBS Journal, EarlyView.
This study shows how a common genetic variant of mitochondrial topoisomerase 1 (TOP1MT rs2293925) can influence mitochondrial gene regulation, DNA topology, and formation of noncanonical nucleic acid structures such as R‐loops. By linking this enhancer‐active variant to mitochondrial nucleic acid stress in cellular contexts relevant to amyotrophic ...
Dóra Varga, Zsolt Ráduly, Beáta Boros‐Oláh, Éva Nagy, Zsolt Karányi, László Halász, Bálint László Bálint, György Vámosi, Emese Tóth, Péter Bai, Serena Santangelo, Patrizia Bossolasco, Antonia Ratti, Vincent Géli, Yves Pommier, Lóránt Székvölgyi   +15 more
wiley   +1 more source