Results 91 to 100 of about 34,144 (356)

Topotecan lacks third space sequestration [PDF]

, 2000
The objective of this study was to determine the influence of pleural and ascitic fluid on the pharmacokinetics of the antitumor camptothecin derivative topotecan.
Gelderblom, A.J. (Hans), Jonge, M.J.A. (Maja) de, Loos, W.J. (Walter), Sparreboom, A. (Alex), Verweij, J. (Jaap)   +4 more
core   +1 more source

Significance of thromboxane A2 and prostaglandin I2 in acute necrotizing pancreatitis in rats [PDF]

, 1990
Plasma thromboxane concentrations were found to be significantly elevated in acute necrotizing pancreatitis in rats, whereas prostaglandin I2 levels were not. The significance of these alterations was investigated. Pancreatitis was induced by injecting 5%
Kort, W.J. (Wil), Ooijen, B. (B.) van, Tinga, C.J. (Cor), Wilson, J.H.P. (Paul)   +3 more
core   +1 more source

Detecting TP53 mutations in paired liquid and tissue biopsies from patients with high‐grade serous ovarian carcinoma

International Journal of Cancer, EarlyView.
What's New? High‐grade serous ovarian carcinoma is often diagnosed at advanced stages due to non‐specific symptoms and the lack of reliable screening methods. This proof‐of‐concept study introduces a novel TP53 mutation panel using unique molecular identifier‐based next‐generation sequencing for sensitive detection of high‐grade serous ovarian ...
Amanda Olsson Widjaja, Peter Micallef, Maria Lycke, Tobias Österlund, Manuel Luna Santamaría, Julia Hedlund Lindberg, Therese Carlsson, Ulf Gyllensten, Anders Ståhlberg, Benjamin Ulfenborg, Anna Linder, Karin Sundfeldt   +11 more
wiley   +1 more source

The diagnostic utility of cell block as an adjunct to cytological smears [PDF]

, 2014
Objectives: Cytological examination of serous fluids is of paramount importance in detecting cancer cells. Distinguishing malignant cells from benign reactive mesothelial cells in fluid cytology is an everyday diagnostic problem. Cell blocks are valuable
Bhavana Grandhi, Vissa Shanthi, Mohan Rao N, Chidananda Reddy V, Venkata MuraliMohan K
core   +1 more source

A personal 360° view of applications of ‘biomimetic’ molecular recognition

Journal of Chemical Technology &Biotechnology, EarlyView.
Abstract Molecular recognition between biological molecules has formed the basis for innumerable applications in biotechnology for the last seven decades or so. Techniques such as affinity chromatography, solid‐phase and aqueous two‐phase extraction, affinity precipitation, biomimetic catalytic systems, biosensors and molecular imprinting all exploit ...
Christopher R Lowe
wiley   +1 more source

Diagnosis of spontaneous bacterial peritonitis

The Egyptian Journal of Internal Medicine, 2014
Background Spontaneous infection of ascites is a severe complication of ascites and must be actively searched for. Many studies have been carried out on inflammatory markers and their levels in serum and ascitic fluid such as complement 3 (C3 ...
Naglaa A El-Gendy, Naglaa A Tawfeek, Rayyh A Saleh, Enas E Radwan, Eman E Ahmad, Rehab A Mohammed   +5 more
doaj   +1 more source

Tuberculous Peritonitis Presenting Acute Recurrent Pancreatitis [PDF]

, 2009
Tuberculosis (TB), one of the oldest diseases known to affect humans, is a major cause of death worldwide. TB is still a major problem in Indonesia. This disease, which is caused by bacteria of the Mycobacterium tuberculosis, usually affects the lungs ...
Abdullah, M. (Murdani), Is, A. (Afifah), Karim, B. (Birry), Pitoyo, C. W. (Ceva), Rinaldi, I. (Ikhwan), Syam, A. F. (Ari)   +5 more
core   +1 more source

Klippel‐Trénaunay‐Weber Syndrome: Prenatal Diagnosis and Review of the Literature

Journal of Clinical Ultrasound, Volume 53, Issue 3, Page 535-546, March/April 2025.
This meta‐analysis demonstrates the high diagnostic accuracy of SZ‐CEUS for differentiating between malignant and benign focal liver lesions, as well as for HCC from non‐HCC lesions. The study shows better performance for smaller lesions and those with a higher proportion of malignancy.
Giuliana Orlandi, Laura Sarno, Antonio Angelino, Mariarosaria Motta, Raffaella Di Girolamo, Luigi Carbone, Marika Rovetto, Laura Letizia Mazzarelli, Gabriella Sglavo, Francesco D' Antonio, Ilenia Mappa, Daniele Di Mascio, Giuseppe Rizzo, Giuseppe Maria Maruotti   +13 more
wiley   +1 more source

An Indonesian Male with Abdominal Pain and Weight Loss: Abdominal Tuberculosis Presenting with Cervical Lymph Node Enlargement [PDF]

, 2012
Case A 21-year-old Indonesian male presented with a 6-month history of abdominal pain. The pain was described as a diffuse cramping that was worse with movement and after meals. He reported early satiety, and the pain was improved at rest.
Kaye, MD, Leah Duke, Littlejohn, MD, Jayne   +1 more
core   +2 more sources

Abdominal POCUS Education for Clinicians: A Systematic Review of Teaching Methods for Point‐of‐Care Abdominal Ultrasonography

Journal of Clinical Ultrasound, Volume 53, Issue 3, Page 547-561, March/April 2025.
For patients to benefit from abdominal point‐of‐care ultrasound, the ultrasound examinator must be sufficiently trained. In this systematic review, we identified advantages and disadvantages of different training methods and approaches. We conclude that thoughtful integration of the various educational methods is crucial for stakeholders and educators.
Birkir Örn Sveinsson, Olof Kristin Thorsteinsdottir, Alexander G. P. Browne, Benjamin S. B. Rasmussen, Anders Bo Nielsen, Pia Iben Pietersen   +5 more
wiley   +1 more source