Results 71 to 80 of about 2,415,424 (293)

A Spatially Directed Microneedle Patch Enables Intratumoral Co‐Delivery of FOLFIRINOX, Surufatinib, and Anti‐PD‐1 for Chemo‐Immunotherapy of Pancreatic Ductal Adenocarcinoma

Advanced Science, EarlyView.
A double‐layered shell‐core microneedle patch is developed to co‐deliver FOLFIRINOX, surufatinib, and anti‐PD‐1 for localized chemo‐immunotherapy of PDAC. This strategy achieves sustained tumor suppression, reduces metastasis, and reprograms the TME by enhancing CD8+ T‐cell infiltration and inhibiting Tregs and M2 macrophages infiltration, while ...
Tingting Kong, Ximo Xu, Xiao Zhang, Chuntao Wu, Zhengjun Qiu, Beiyuan Hu, Zihao Qi, Qiang Tian, Yuqin Yang, Hanguang Dong, Fei Wu, Tuo Jin, Yan Zheng, Jiang Long   +13 more
wiley   +1 more source

Dissimilar populations of EpСam-positive cells in ascitic fluid of ovarian cancer patients: a relationship with the degree of carcinomatosis

Бюллетень сибирской медицины, 2021
Background. Peritoneal carcinomatosis (PC) is one of the most unfavorable factors of ovarian cancer progression. It is often accompanied by accumulation of fluid in the abdominal cavity, which is called ascites.
E. V. Kaigorodova, M. O. Ochirov, S. V. Molchanov, R. R. Rogachev, D. A. Dyakov, A. L. Chernyshova, O. V. Shpileva, O. I. Kovalev, S. V. Vtorushin   +8 more
doaj   +1 more source

A study of biochemical parameters and microbial organisms in ascitic fluid of spontaneous bacterial peritonitis patients [PDF]

, 2018
Introduction:Spontaneous Bacterial Peritonitis (SBP) is recognized as a severe complication in patients of ascites. In recent years, it has also been diagnosed in patients without liver disease.
Waran, Marcia, Tyagi, Arun, Srivastava, A.K., Gadekar, Rahul   +3 more
core   +2 more sources

Clinically Informed Intelligent Classification of Ovarian Cancer Cells by Label‐Free Holographic Imaging Flow Cytometry

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
Quantitative phase maps of single cells recorded in flow cytometry modality feed a hierarchical architecture of machine learning models for the label‐free identification of subtypes of ovarian cancer. The employment of a priori clinical information improves the classification performance, thus emulating the clinical application of liquid biopsy during ...
Daniele Pirone, Beatrice Cavina, Daniele Gaetano Sirico, Martina Mugnano, Vittorio Bianco, Lisa Miccio, Anna Myriam Perrone, Anna Maria Porcelli, Giuseppe Gasparre, Ivana Kurelac, Pasquale Memmolo, Pietro Ferraro   +11 more
wiley   +1 more source

The actions of human atrial natriuretic factor on hepatic arterial and portal vascular beds of the anaesthetized dog [PDF]

, 1990
1. The vascular actions of atrial natriuretic factor (ANF) have been assessed with other vasoactive agents on the hepatic arterial and portal vascular beds of the anaesthetized dog. 2.
Dhume, V. G., Withrington, P. G., Croxton, R., Gerbes, Alexander L.   +3 more
core  

Spontaneous bacterial peritonitis results in oxidative and nitrosative stress in ascitic fluid [PDF]

, 2007
Background and Aim: Spontaneous bacterial peritonitis (SBP) is a major complication of liver cirrhosis and accounts for significant mortality. Although oxygen free radicals and nitric oxide been implicated in the pathophysiology of liver cirrhosis ...
Sophia Amalanathan, Amalanathan, Sophia, Kunissery A Balasubramanian, Ramachandran, Anup, Kurian, George, Anup Ramachandran, Balasubramanian, Kunissery A., Sathish Kumar Natarajan, George Kurian, Natarajan, Sathish Kumar, Mukhopadhya, Ashis, Ashis Mukhopadhya   +11 more
core   +1 more source

POEMS Syndrome: 2026 Update on Diagnosis, Risk‐Stratification, and Management

American Journal of Hematology, EarlyView.
ABSTRACT Disease Overview POEMS syndrome is a life‐threatening syndrome due to an underlying plasma cell neoplasm. The major criteria for the syndrome are polyneuropathy, clonal plasma cell disorder (PCD), sclerotic bone lesions, elevated vascular endothelial growth factor, and the presence of Castleman disease.
Angela Dispenzieri
wiley   +1 more source

Spontaneous bacterial peritonitis among adult patients with ascites attending Korle-bu Teaching Hospital [PDF]

Ghana Medical Journal, 2019
Background: Spontaneous bacterial peritonitis (SBP) is one of the most common and life-threatening complications of ascites, mostly in patients with cirrhotic ascites and children with nephrotic syndrome.
Amoako Duah, Kofi N. Nkrumah
doaj   +1 more source

Carcinoembryonic antigen in ovarian cancer: Correlation of concentrations in tumour tissue, cyst fluid, ascitic fluid and peripheral blood [PDF]

, 1982
Summary: The interpretation of CEA levels in patients with malignant disease is still difficult in some instances because of lack of knowledge of the factors which influence the concentrations of CEA in peripheral blood.
Mackay E.V., Hill R., Khoo S.K., Daunter B.   +3 more
core   +1 more source

Lymphatic Abnormalities in Noonan Syndrome Extend Beyond Clinically Apparent Disease

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Lymphatic disease represents a well‐described manifestation of Noonan syndrome (NS), yet the full phenotypic spectrum remains incompletely characterized, especially in asymptomatic individuals. We conducted a cross‐sectional study including 10 individuals with NS (four with peripheral lymphedema and six without) and 10 age‐ and sex‐matched ...
Inger Norlyk Sheyanth, Benjamin Kelly, Sheyanth Mohanakumar, Steffen Ringgaard, Yoav Dori, Irene Kibæk Nielsen, Uffe Birk Jensen, Vibeke Elisabeth Hjortdal   +7 more
wiley   +1 more source