Results 161 to 170 of about 21,377 (247)

Preoperative Avapritinib for Localized PDGFRA‐Mutant GIST: Marked Pathologic Response, but Limited Feasibility at Standard Dosing

Cancer Medicine, Volume 15, Issue 8, August 2026.
In this two‐center retrospective series of eight patients with localized PDGFRA‐mutant gastric GIST treated with preoperative avapritinib, therapy produced substantial antitumor activity, including tumor reduction in 7 of 8 patients and complete or near‐complete pathologic response in all resected patients.
Tannaz Ranjbarian, Mark Antkowiak, Shirley Sarno, Shumei Kato, Adam M. Burgoyne, Skye C. Mayo, Michael C. Heinrich, Paul T. Fanta, Jason K. Sicklick   +8 more
wiley   +1 more source

How Do Polymorphonuclear Counts in Ascitic Fluid Correlate to Hospital Outcome. [PDF]

J Community Hosp Intern Med Perspect
Haddadin R, Ghobrial M, Tabbah T, Trad G, Ryan J, Gish RG, Shah P.   +6 more
europepmc   +1 more source

The Unusual Coexistence of Chronic Lymphocytic Leukemia, Dengue Fever, and Acute Kidney Injury: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT A 70‐year‐old male with CLL presented with dengue fever complicated by AKI. A diagnostic challenge arose from overlapping features. Investigations showed leukocytosis, lymphocytosis, anemia, thrombocytopenia, positive Anti‐Dengue IgM, and renal impairment. Managed with supportive care, ibrutinib, and monitoring, with improvement.
Musawer Khan, Safia Bibi, Zarafshan Khan, F. N. U. Ruqayya, Arwaa Chaudhry, Nauman Khan, Alamzaib Khan, Kamil Ahmad Kamil, F. N. U. Zainullah   +8 more
wiley   +1 more source

The prognostic significance of HDL-associated apolipoproteins in ascitic fluid from patients with cirrhosis and spontaneous bacterial peritonitis. [PDF]

Sci Rep
Murad M, Reuken PA, Schubert K, Reißing J, Ibidapo-Obe O, Große K, Frissen M, Haedge F, El-Hassani M, von Bergen M, Bruns T.   +10 more
europepmc   +1 more source

Disulfiram‐Induced Hepatotoxicity in a Patient With Alcohol Use Disorder: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Disulfiram can cause severe and potentially fatal hepatotoxicity, particularly in patients with preexisting liver disease. In Bhutan, where alcohol‐related liver disease represents a major public health burden and pharmacological options for relapse prevention remain limited, careful patient selection, hepatic assessment, and early monitoring ...
Sonam Wangchuk, Bikram Chhetri, Jiann Lin Loo   +2 more
wiley   +1 more source

Consumed by Abdominal Distention

Arthritis Care &Research, Volume 78, Issue 8, Page 959-966, August 2026.
Abimbola Fadairo‐Azinge, James Grenert, Brian Haas, Mary Margaretten   +3 more
wiley   +1 more source

Peritoneal Tuberculosis Presenting as Massive Ascites in Pregnancy: A Case Report

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Abdominal tuberculosis, especially peritoneal tuberculosis, is uncommon in pregnancy. The diagnosis during pregnancy is a challenge due to many signs and symptoms being nonspecific and mimicking the symptoms of pregnancy. The presence of ascites, with anorexia and weight loss in pregnancy from endemic regions, should be addressed with ...
S. Gyamtsho, S. Dechen, S. Choden
wiley   +1 more source

Mast Cell Sarcoma of the Small Intestine Diagnosed by Ascitic Fluid Cytology: A Case Report with Molecular and Immunophenotypic Correlation. [PDF]

Acta Cytol
Mizoguchi K, Tsuji K, Teramoto Y, Otsuki S, Fujimoto M, Watanabe M, Oshima S, Shimizu T, Yoshinaga N, Ito H, Furuhata A, Hirata M, Haga H.   +12 more
europepmc   +1 more source

Primary Cervical Angiosarcoma Presenting With Transfusion‐Dependent Bleeding in Early Pregnancy: Diagnostic and Management Challenges

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Persistent vaginal bleeding during pregnancy should not be attributed solely to obstetric causes. Rare cervical malignancies, including angiosarcoma, may present with life‐threatening anemia, and MRI with early biopsy is essential to avoid diagnostic delay.
Ammir Abuzahra, Ruba Atawneh, Siwar Abu Sakout, Raya Abu Ayyash, Jana Dwaik   +4 more
wiley   +1 more source

Structure‐Based Design, Synthesis, and Biological Evaluation of Oxadiazole–Morpholine Hybrids as Potent PARP‐1 Inhibitors Inducing Apoptosis in Breast Cancer Cells

Drug Development Research, Volume 87, Issue 5, August 2026.
ABSTRACT Poly(ADP‐ribose) polymerase‐1 (PARP‐1) plays a central role in the repair of DNA single‐strand breaks and represents an established therapeutic target in cancer treatment. In this study, a series of novel oxadiazole–morpholine hybrid compounds was designed and synthesized using a structure‐based drug design approach to target the catalytic ...
Nader R. Albujuq, Khaled M. Darwish, Sherif Ashraf Fahmy, Buthaina Hussein, Ghada G. Kayed, Musa A. Said, Mohamed S. Nafie   +6 more
wiley   +1 more source