Results 221 to 230 of about 2,405,617 (334)

T Cell Exhaustion in Cancer Immunotherapy: Heterogeneity, Mechanisms, and Therapeutic Opportunities

open access: yesAdvanced Science, Volume 13, Issue 35, 24 June 2026.
T cell exhaustion limits immunotherapy efficacy. This article delineates its progression from stem‐like to terminally exhausted states, governed by persistent antigen, transcription factors, epigenetics, and metabolism. It maps the exhaustion landscape in the TME and proposes integrated reversal strategies, providing a translational roadmap to overcome
Yang Yu   +7 more
wiley   +1 more source

Laparoscopic Delivery of a MnO2‐P‐ICG Patch for Photodynamic Therapy and NK Cell‐Driven Immunotherapy in Hepatocellular Carcinoma

open access: yesAdvanced Science, Volume 13, Issue 32, 9 June 2026.
This study proposes a flexible MnO2‐P‐ICG nanofiber patch for laparoscopic treatment of liver tumors. The patch alleviates tumor hypoxia and induces photodynamic therapy (PDT) triggered immunogenic cell death, thereby activating the cGAS‐STING pathway and, in synergy with pachymaran, promoting NK cell–mediated innate immunity. This synergistic strategy
Jie Lin   +14 more
wiley   +1 more source

Artificial-Intelligence-Assisted Detection of Metastatic Colorectal Cancer Cells in Ascitic Fluid. [PDF]

open access: yesCancers (Basel)
Kim HK   +11 more
europepmc   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale   +5 more
wiley   +1 more source

Microbiological profile of ascitic fluid infection at Mohammed VI University Hospital in Oujda: A prospective and descriptive study. [PDF]

open access: yesTunis Med
Ghomari K   +10 more
europepmc   +1 more source

Docetaxel‐Induced Serositis Mimicking Malignant Pleural Effusion

open access: yesClinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Pleural effusions are common in patients with cancer. Although their development may signal progressive malignant disease, drug‐induced effusions are a rare and often overlooked cause of exudative pleural effusions. We describe a 50‐year‐old woman with recurrent granulosa cell tumor of the ovary who developed bilateral pleural and pericardial ...
Muhammad Anees   +4 more
wiley   +1 more source

Ascitic Fluid Lactate Level as a Predictor of Mortality in Cirrhotic Patients Having Spontaneous Bacterial Peritonitis (SBP). [PDF]

open access: yesCureus
Kumar D   +9 more
europepmc   +1 more source

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