Results 201 to 210 of about 6,132,688 (306)

Chemotherapeutic Potential of Fluorouracil‐Platinum (IV) Prodrugs Against Cisplatin‐Resistant Colorectal Cancer Cells

Chemistry – A European Journal, EarlyView.
ABSTRACT Fluorouracil‐platinum(IV) prodrugs represent a novel class of multimechanistic chemotherapeutics with enhanced anticancer potential. The prodrugs PtIVP‐5FUMeOBut and PtIV56‐5FUMeOBut were actualized by derivatising the clinical drug 5‐fluorouracil (5FU) and coordinating it to platinum(IV) complexes, leveraging the established cytotoxicity of ...
Maria George Elias, Aleen Khoury, Shadma Fatima, Timothy J. Mann, Shawan Karan, Meena Mikhael, Paul de Souza, Christopher P. Gordon, Kieran F. Scott, Janice R. Aldrich‐Wright   +9 more
wiley   +1 more source

Sodium ascorbate versus ascorbic acid in sepsis: a narrative review of emerging cardiovascular and neurological benefits. [PDF]

Crit Care
Bishop MS, Lane DJR, Ayton S, May CN, Plummer MP, Lankadeva YR.   +5 more
europepmc   +1 more source

Carbon Dots for Cancer Theranostics: Synthesis Strategies, Luminescence Properties, and Advances in Bioimaging‐Guided Diagnosis and Therapy

Chemistry – A European Journal, EarlyView.
Lighting up the path to precision oncology: This review comprehensively summarizes the rational design of carbon dots (CDs), elucidating how core size, surface chemistry, and heteroatom doping dictate their luminescence mechanisms. Special emphasis is placed on engineering NIR‐II emissive CDs for deep‐tissue imaging.
Zekun Yan, Yupeng Liu, Jinyun Tan, Songnan Qu   +3 more
wiley   +1 more source

Radioprotective Effect of Ascorbic Acid: A Need for Prophylactic Supplementation Pre- and Post-Radiation Exposure Among Patients and Healthcare Workers-A Perspective Article. [PDF]

Health Sci Rep
Mushemba J, Angolile CM, Kabuhaya JF, Mashauri HL.   +3 more
europepmc   +1 more source

Impact of Organo‐Functionalization on the Light‐Driven Hydrogen Evolution Reactivity of Molecular Molybdenum Sulfides

Chemistry – A European Journal, EarlyView.
Organo‐functionalized molecular molybdenum sulfides were synthesized using bidentate N‐donor ligands and investigated as light‐driven homogeneous hydrogen evolution reaction (HER) catalysts. Trends observed in the HER activity of these catalysts were elucidated by combining photophysical, electrochemical and computational studies.
Moritz Jahn, Luis Kammerer, Luca Schleicher, Amelie Meyer, Mariet Sibi Puthanagady, Alexander K. Mengele, Sven Rau, Stephan Kupfer, Benjamin Dietzek‐Ivanšić, Carsten Streb   +9 more
wiley   +1 more source

Evaluation of ascorbic acid as an intervention of metal toxicity in dogs in Kabwe district. [PDF]

Vet Anim Sci
Banda N, Selwa M, Doya R, Soe NC, Kataba A, Yabe J, Zyambo G, Muzandu K, Yohannes YB, Ikenaka Y, Ishizuka M, Nakayama SM.   +11 more
europepmc   +1 more source

Synergistic Action of Ascorbic Acid and Readily Accessible NHC^N Ligands for the Oxidation of Gold(I) With Electron‐Rich Aryldiazonium Salts

Chemistry – A European Journal, EarlyView.
The synergic action of ascorbic acid and NHC^N ligands enables Au(I) oxidation with electron‐rich aryldiazonium salts. ABSTRACT The synergistic action of ascorbic acid and NHC^N ligands enables the challenging oxidation of Au(I) with electron‐rich aryldiazonium salts in the absence of a cocatalyst and/or irradiation. EPR, NMR, and x‐ray analyses reveal
Paula G. Cárdenas‐Cárdenas, Diego Dusso, Saúl Soto‐Zúñiga, Osvaldo F. López‐Saladino, Simón Hernández‐Ortega, Rubén A. Toscano, Virginia Gómez‐Vidales, Susana Porcel‐García   +7 more
wiley   +1 more source

Anticancer Effects of Ascorbic Acid: Not All Sides Fit All. [PDF]

Cancers (Basel)
Arunsi UO, Olugbami JO, Oyelere AK.
europepmc   +1 more source

An Electrophilic Uridine Building Block for Post‐Synthetic RNA Modification as Exemplified for Spin Labeling

Chemistry – A European Journal, EarlyView.
An electrophilic 5‐isothiocyanatomethyl uridine building block enables modular post‐synthetic RNA labeling with primary amine‐containing probes. Positioning the functionality in the major groove minimizes structural perturbation and allows facile conjugation of sensitive tags such as TEMPO spin labels for paramagnetic relaxation enhancement studies ...
Lisa Ruetz, Sonja Leiner, Alessandro Marotto, Raphael Plangger, Christoph Kreutz   +4 more
wiley   +1 more source

Exogenous ascorbic acid enhances drought tolerance in Hypericum perforatum L. by modulating antioxidant defense and osmotic adjustment. [PDF]

Sci Rep
Asadi F, Etemadi N, Amirikhah R, Mosaddeghi MR, Aalipour H.   +4 more
europepmc   +1 more source