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Atherosclerotic cardiovascular disease (ASCVD) and obesity pose challenges to patients, healthcare professionals (HCPs), and health systems. The aim of this study was to understand the journey of patients with ASCVD and obesity, their caregivers, and ...
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Targeting Lp(a) to reduce ASCVD risk
Nature Reviews Cardiology, 2020In a prespecified secondary analysis of the ACCELERATE trial, Puri and colleagues report a stepwise relationship between lipoprotein(a) levels and risk of major adverse cardiac events in patients with high-sensitivity C-reactive protein levels ≥2 mg/l.
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Renin angiotensin system and ASCVD
Current Opinion in Cardiology, 2000The renin angiotensin system was first described over 100 years ago and is still the focus of intense clinical and basic science investigation. The renin angiotensin system was demonstrated to play a major pathogenetic role in hypertension. The development of inhibitors of angiotensin-converting enzyme and specific receptor blockers for angiotensin-II ...
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Detecting and Managing ASCVD in Women: A Focus on Statins
The Journal of Family Practice, 2022At the end of the activity, participants will be able to:Summarize important findings and trends involving women and atherosclerotic cardiovascular disease (ASCVD). Characterize the multiple cardiometabolic changes that occur during menopause and the associated ASCVD risk.
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HDL cholesterol and ASCVD risk stratification: A debate
Atherosclerosis, 2019This debate is designed to review the usefulness of the cholesterol mass within high-density lipoproteins (HDL-C) to predict the risk of atherosclerotic cardiovascular disease (ASCVD). PRO: There is much current confusion regarding the role of high density lipoproteins (HDLs) in atherosclerotic cardiovascular disease (ASCVD). While it is an established
Philip Barter, Jacques Genest
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ASCVD- Should We Treat It or Eradicate?
Research International Journal of Cardiology and Cardiovascular Medicine, 2023Editorial Note Atherosclerotic cardiovascular disease (ASCVD) is a leading global health concern, signiϐicantly contributing to acute cardiovascular events such as myocardial infarction and ischemic stroke. Research consistently links elevated levels of low-density lipoprotein cholesterol (LDL-C) to ASCVD.
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Treatment Thresholds and ASCVD Risk
Journal of the American College of Cardiology, 2021openaire +2 more sources
Aspirin dosing for secondary prevention in ASCVD
Nature Reviews Cardiology, 2021openaire +2 more sources
2019
While the cardioprotective effect of statins are undeniable, experimental and observational research has suggested the potential for increased type 2 diabetes (T2D) risk. However, few studies have directly compared statin-associated benefits and harms or examined heterogeneity by population subgroups or assumed treatment effect.
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While the cardioprotective effect of statins are undeniable, experimental and observational research has suggested the potential for increased type 2 diabetes (T2D) risk. However, few studies have directly compared statin-associated benefits and harms or examined heterogeneity by population subgroups or assumed treatment effect.
openaire +1 more source

