Results 1 to 10 of about 442,632 (268)

Lipoprotein(a) and the atherosclerotic burden – Should we wait for clinical trial evidence before taking action?

Atherosclerosis Plus
The fact that lipoprotein(a) levels should be regarded as a causal residual risk factor in the atherosclerotic cardiovascular diseases (ASCVD) is now a no-brainer.
Isabella Fichtner, Chiara Macchi, Alessandra Stefania Rizzuto, Stefano Carugo, Alberto Corsini, Massimiliano Ruscica   +5 more
doaj   +1 more source

LIPOPROTEIN APHERESIS: YESTERDAY, TODAY, TOMORROW. REVIEW

Российский кардиологический журнал, 2018
The first attempts to treat patients with homozygous familial hypercholesterolemia (HCH) were performed in the 60ies and 70ies using a total plasma exchange. Later on, more specific lipoprotein apheresis (LA) methods have been developed – the replacement
U. Julius, S. Tselmin, S. R. Bornstein
doaj   +1 more source

INFLUENCE OF NICOTINIC ACID ON SUBFRACTIONAL SPECTRUM OF LOW, INTERMEDIATE AND HIGH DENSITY LIPOPROTEINS IN PATIENTS WITH HYPERLIPOPROTEINEMIA(а)

Российский кардиологический журнал, 2017
Aim. To evaluate the influence of nicotinic acid (NA) on subfractional spectrum of proand antiatherogenic lipoproteides in hyperlipoproteidemia (a) patients.Material and methods.
E. A. Utkina, O. I. Afanasieva, N. V. Artemyeva, M. V. Ezhov, S. N. Pokrovsky   +4 more
doaj   +1 more source

Lipoprotein(a) and its Clinical Importance

Medical Laboratory Journal, 2020
Reports have shown that lipoprotein (Lp)(a) can serve as an indicator of atherosclerosis and cardiovascular diseases. Several cardiovascular disease risk factors including age, ethnicity and type 2 diabetes mellitus have been linked to Lp(a) metabolism ...
farnaz zahedi avval, malihe Moammeri Salahshooh, Fatemeh ‎ sadabadi   +2 more
doaj  

Deficient perceptions and practices concerning elevated lipoprotein(a) among specialists in Singapore

Frontiers in Cardiovascular Medicine
BackgroundMultiple guidelines recommend detection of and early risk factor management for elevated lipoprotein(a) [Lp(a)]. Effective implementation requires assessment of knowledge and practices regarding elevated Lp(a) among medical specialists.AimTo ...
Wann Jia Loh, Wann Jia Loh, Wann Jia Loh, Jing Pang, Oliver Simon, Dick C. Chan, Gerald F. Watts, Gerald F. Watts   +7 more
doaj   +1 more source

Lipoprotein separation in a novel iodixanol density gradient, for composition, density, and phenotype analysis

Journal of Lipid Research, 2008
Separation of lipoproteins by traditional sequential salt density floatation is a prolonged process (∼72 h) with variable recovery, whereas iodixanol-based, self-generating density gradients provide a rapid (∼4 h) alternative.
Michael S. Yee, Darrell V. Pavitt, Tira Tan, Soundararajan Venkatesan, Ian F. Godsland, William Richmond, Desmond G. Johnston   +6 more
doaj   +1 more source

Lipoprotein glomerulopathy

Current Opinion in Lipidology, 2011
Lipoprotein glomerulopathy is a rare disorder characterized by proteinuria, renal insufficiency and disturbances in lipoprotein metabolism closely related to those observed in type III hyperlipidemia. Rare mutations in apolipoprotein E (apoE) gene may contribute to the pathogenesis of the disease.
Tsimihodimos, V., Elisaf, M. S.
openaire   +3 more sources

Genome-wide association study of genetic determinants of LDL-c response to atorvastatin therapy: importance of Lp(a)

Journal of Lipid Research, 2012
We carried out a genome-wide association study (GWAS) of LDL-c response to statin using data from participants in the Collaborative Atorvastatin Diabetes Study (CARDS; n = 1,156), the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT; n = 895), and the ...
Harshal A. Deshmukh, Helen M. Colhoun, Toby Johnson, Paul M. McKeigue, D. John Betteridge, Paul N. Durrington, John H. Fuller, Shona Livingstone, Valentine Charlton-Menys, Andrew Neil, Neil Poulter, Peter Sever, Denis C. Shields, Alice V. Stanton, Aurobindo Chatterjee, Craig Hyde, Roberto A. Calle, David A. DeMicco, Stella Trompet, Iris Postmus, Ian Ford, J. Wouter Jukema, Mark Caulfield, Graham A. Hitman   +23 more
doaj   +1 more source

A novel immune-isolation method for direct quantification of triglycerides associated with lipoprotein(a)

Journal of Lipid Research
Lipoprotein (a) [Lp(a)] is viewed as a cholesterol-rich, LDL-like particle, yet potential heterogeneity in its lipid composition is not well understood.
Lizhu Lin, Fei Su, Calvin Yeang, Sotirios Tsimikas   +3 more
doaj   +1 more source

Small size apolipoprotein(a) isoforms enhance inflammatory and proteolytic potential of collagen-primed monocytes

Lipids in Health and Disease, 2019
Background Atherosclerosis is an inflammatory process involving activation of monocytes recruited by various chemoattractant factors, among which lipoprotein(a) and its specific apolipoprotein apo(a). Lp(a) contains a specific apolipoprotein apo(a) which
Nadia Sabbah, Stéphane Jaisson, Roselyne Garnotel, Eduardo Anglés-Cano, Philippe Gillery   +4 more
doaj   +1 more source