Results 1 to 10 of about 458,527 (308)
Fluid-structure interactions (FSI) based study of low-density lipoproteins (LDL) uptake in the left coronary artery. [PDF]
Sci Rep, 2021 The purpose of this study is to compare the effect of the different physical factors on low-density lipoproteins (LDL) accumulation from flowing blood to the arterial wall of the left coronary arteries.
Chen X, Zhuang J, Huang H, Wu Y.
europepmc +2 more sources
Approaches to Visualising Endocytosis of LDL-Related Lipoproteins [PDF]
Biomolecules, 2022 Endocytosis is the process by which molecules are actively transported into cells. It can take on a variety of forms depending on the cellular machinery involved ranging from specific receptor-mediated endocytosis to the less selective and actin-driven macropinocytosis.
Halima Siddiqui +3 more
openaire +3 more sources
Clinical & Translational Immunology, 2021 Objectives The NLRP3 inflammasome plays a key role in arterial wall inflammation. In this study, we elucidated the role of serum lipoproteins in the regulation of NLRP3 inflammasome activation by serum amyloid A (SAA) and other inflammasome activators ...
Katariina Nurmi +13 more
doaj +1 more source
Lipoprotein lipase-facilitated uptake of LDL is mediated by the LDL receptor [PDF]
Journal of Lipid Research, 2007 LPL mediates the uptake of lipoproteins into different cell types independent of its catalytic activity. The mechanism of this process and its physiological relevance are not clear. Taking into account the importance of the endothelial barrier for lipoprotein uptake, in vitro studies with primary aortic endothelial cells from wild-type and low density ...
Britta Loeffler +6 more
openaire +3 more sources
Molecular Neurodegeneration, 2023 This narrative review focuses on the role of cholesteryl ester transfer protein (CETP) and peripheral lipoproteins in the vascular contributions to cognitive impairment and dementia (VCID).
Tetiana Poliakova, Cheryl L. Wellington
doaj +1 more source
Bleeding, Thrombosis and Vascular Biology, 2022 The anticoagulant protein S (PS) binds phospholipids with very high affinity, but PS interaction with lipoproteins and lipidrich atherosclerotic plaques remains still poorly defined.
Marcello Baroni +8 more
doaj +1 more source
Molecular and Cellular Mechanisms of Electronegative Lipoproteins in Cardiovascular Diseases
Biomedicines, 2020 Dysregulation of glucose and lipid metabolism increases plasma levels of lipoproteins and triglycerides, resulting in vascular endothelial damage. Remarkably, the oxidation of lipid and lipoprotein particles generates electronegative lipoproteins that ...
Liang-Yin Ke +6 more
doaj +1 more source
European Heart Journal, 2021 Recent advances in human genetics, together with a large body of epidemiologic, preclinical, and clinical trial results, provide strong support for a causal association between triglycerides (TG), TG-rich lipoproteins (TRL), and TRL remnants, and ...
H. Ginsberg +21 more
semanticscholar +1 more source
European Heart Journal, 2023 Aims The strength of the relationship of triglyceride-rich lipoproteins (TRL) with risk of coronary heart disease (CHD) compared with low-density lipoprotein (LDL) is yet to be resolved.
Elias Björnson +6 more
semanticscholar +1 more source
Atherosclerosis Development and Progression: The Role of Atherogenic Small, Dense LDL
Medicina, 2022 Atherosclerosis is responsible for large cardiovascular mortality in many countries globally. It has been shown over the last decades that the reduction of atherosclerotic progression is a critical factor for preventing future cardiovascular events.
J. Vekić +6 more
semanticscholar +1 more source