Results 1 to 10 of about 6,562 (204)
Expression of type III hyperlipoproteinemia in apolipoprotein E2 (Arg158 --> Cys) homozygotes is associated with hyperinsulinemia [PDF]
, 2002 Type III hyperlipoproteinemia (HLP) is mainly found in homozygous carriers of apolipoprotein E2 (apoE2, Arg158-->Cys). Only a small percentage (< 5%) of these apoE2 homozygotes develops hyperlipidemia, indicating that additional environmental and genetic
Beer, F. (Femke) de +7 more
core +15 more sources
2022 Consensus statement on the management of familial hypercholesterolemia in Korea [PDF]
The Korean Journal of Internal Medicine, 2022 Familial hypercholesterolemia (FH) is the most common monogenic disorder. Due to the marked elevation of cardiovascular risk, the early detection, diagnosis, and proper management of this disorder are critical.
Chan Joo Lee +6 more
doaj +1 more source
Role of PCSK9 Inhibitors in Patients with Familial Hypercholesterolemia [PDF]
Endocrinology and Metabolism, 2021 Patients with familial hypercholesterolemia (FH) are at high or very high risk for cardiovascular disease. Those with heterozygous FH (HeFH) often do not reach low-density lipoprotein cholesterol (LDL-C) targets with statin and ezetimibe therapy, and ...
Brian Tomlinson +3 more
doaj +1 more source
Research in Cardiovascular Medicine, 2022 Background: Familial hypercholesterolemia (FH) is an inherited disorder characterized by significantly elevated levels of low-density lipoprotein (LDL) cholesterol and is usually diagnosed after the occurrence of major adverse cardiovascular event.
Edin Begic +17 more
doaj +1 more source
Interaction between Glucose and Lipid Metabolism: More than Diabetic Dyslipidemia [PDF]
Diabetes & Metabolism Journal, 2015 Glucose and lipid metabolism are linked to each other in many ways. The most important clinical manifestation of this interaction is diabetic dyslipidemia, characterized by elevated triglycerides, low high density lipoprotein cholesterol (HDL-C), and ...
Klaus G. Parhofer
doaj +1 more source
Molecular diagnosis methods in familial hypercholesterolemia
Anatolian Journal of Cardiology, 2020 Familial hypercholesterolemia (FH) is considered the genetic cause of coronary heart disease and ischemic stroke. FH is mainly an autosomal codominant pattern-based disorder and is primarily determined by point mutations within the low-density ...
Valeriu Moldovan +2 more
doaj +1 more source
Relation of hyperlipidemia in serum and loss of high density lipoproteins in urine in the nephrotic syndrome [PDF]
, 1987 The mechanism leading to hyperlipidemia in the nephrotic syndrome is not fully understood but may be related in part to loss of high density lipoproteins in the urine of patients with nephrosis.
Appel +22 more
core +1 more source
Journal of Lipid Research, 1982 Cholesteryl ester-rich beta-very low density lipoproteins (beta-VLDL) are beta-migrating lipoproteins that accumulate in the d < 1.006 g/ml fraction of plasma from cholesterol-fed animals and from patients with Type III hyperlipoproteinemia.
M Fainaru +3 more
doaj +1 more source
Update on Familial Hypercholesterolemia: Diagnosis, Cardiovascular Risk, and Novel Therapeutics [PDF]
Endocrinology and Metabolism, 2017 In recent studies, the reported prevalence of heterozygous familial hypercholesterolemia (FH) has been higher than in previous reports. Although cascade genetic screening is a good option for efficient identification of affected patients, diagnosis using
Sang-Hak Lee
doaj +1 more source
A case report of palmar xanthoma with xanthomatous neuropathy
SAGE Open Medical Case Reports, 2021 Xanthomas are plaques or nodules consisting of an accumulation of excess lipids, resulting in the formation of foam cells in the skin or tendons. Typically, xanthomas are not accompanied by other symptoms. Here, we report a patient with a presentation of
Hyun Yi Lee, Dae Won Koo, Joong Sun Lee
doaj +1 more source