Results 11 to 20 of about 12,443,450 (160)

Ghrelin Levels in Male Patients with Hyperlipoproteinemia I, II versus Type 2 Diabetes Mellitus.

مجلة كلية الطب, 2014
Background; Hyperlipoproteinemia (HLP)  are divided in primary and secondary subtypes. Primary HLP is usually due to genetic causes. Secondary HLP is resulting from another underlying disorder such as diabetes mellitus that leads to alterations in plasma
Salma A. Abbas, Samir L. Shkhaier, Baydaa A. Abed   +2 more
doaj   +2 more sources

Pseudohomozygous Type II Hyperlipoproteinemia

Dermatologica, 1991
Nodular xanthomas on both elbows and a streak-like xanthoma on the intergluteal area developed in a 4-year-old girl with type IIa hyperlipoproteinemia. She had no disease associated with secondary hypercholesterolemia and no family history of hypercholesterolemia. Her xanthomas regressed under fat restriction diet and cholestyramine therapy.
M. Fujita, S. Okamoto, K. Shirai, Y. Saito, S. Yoshida   +4 more
core   +3 more sources

Pseudohomozygous type II hyperlipoproteinemia [PDF]

Japanese journal of human genetics, 1982
A 12-month-old boy with clinical findings suggestive of homozygous familial hypercholesterolemia, who had no secondary causes of hypercholesterolemia, and whose parents had no lipid abnormalities, was reported. No abnormalities were noted in the low density lipoprotein (LDL) receptor activities of the fibroblasts from patient, parents and sibling.
K, Hamada, T, Tanaka, O, Yoshii, S, Saito, K, Hayakawa, N, Kida, S, Ohtaki, Y, Sakai, H, Mabuchi   +8 more
openaire   +2 more sources

Type II Hyperlipoproteinemia in Mother and Twins [PDF]

Circulation, 1969
A 36-year-old housewife with type II hyperlipoproteinemia became pregnant with twins. Although the pregnancy was uneventful, the serum triglycerides were elevated during the third trimester, the delivery, and early puerperium. The mother had no complications directly related to the pregnancy despite hypercholesterolemia, coronary atherosclerosis, and ...
G B, Lee, G A, Culley, M J, Lawson, L L, Adcock, W, Krivit   +4 more
openaire   +2 more sources

Identification and characterization of two novel mutations in the LPL gene causing type I hyperlipoproteinemia [PDF]

, 2016
BackgroundType 1 hyperlipoproteinemia is a rare autosomal recessive disorder most often caused by mutations in the lipoprotein lipase (LPL) gene resulting in severe hypertriglyceridemia and pancreatitis.ObjectivesThe aim of this study was to identify ...
S. M. Lepore, Lepore, Saverio Massimo, T. P. Leren, S. Romeo, O. Wiklund, B.M. Motta, K. E. Berge, K. Retterstøl, Retterstøl, Kjetil, C. Pirazzi, P. Pingitore, Valenti, Luca, Berge, Knut Erik, R. M. Mancina, L. Valenti, Leren T. P., Retterstol K., Motta B. M., Wiklund O., Lepore S. M., Mancina, Rosellina Margherita,, Romeo, Stefano,, Berge K. E., Leren, Trond P, Mancina R. M., Pingitore, Piero,, Wiklund, Olov,, Motta, Benedetta Maria,, Pingitore P., Valenti L., Pirazzi, Carlo,, Pirazzi C., Romeo S.   +32 more
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Identification and Characterization of Two Novel Compounds: Heterozygous Variants of Lipoprotein Lipase in Two Pedigrees With Type I Hyperlipoproteinemia [PDF]

, 2022
BackgroundType I hyperlipoproteinemia, characterized by severe hypertriglyceridemia, is caused mainly by loss-of-function mutation of the lipoprotein lipase (LPL) gene.
Guimei Li, Yingzhou Shi, Wanyi Zhao, Chao Xu, Yiping Cheng, Xiaolong Jin, Jiajun Zhao, Shuping Wang, Ling Gao, Li Fang, Qiuying Sun, Xiaoyan Han, Sun, Qiuying, Zhao, Jiajun, Gao, Ling, Li, Guimei, Fang, Li, Jin, Xiaolong, Wang, Shuping, Han, Xiaoyan, Cheng, Yiping, Shi, Yingzhou, Zhao, Wanyi, Xu, Chao   +23 more
core   +1 more source

Control of sterol synthesis and of hydroxymethylglutaryl CoA reductase in skin fibroblasts grown from patients with homozygous type II hyperlipoproteinemia

Journal of Lipid Research, 1975
In skin fibroblasts grown from four children with a homozygous form of type II hyperlipoproteinemia, the feedback control of sterol synthesis and the inhibitory effect on hydroxymethylglutaryl (HMG) CoA reductase activity by serum or low density ...
J. Avigan, S.J. Bhathena, M.E. Schreiner
doaj   +1 more source

A case report of palmar xanthoma with xanthomatous neuropathy

SAGE Open Medical Case Reports, 2021
Xanthomas are plaques or nodules consisting of an accumulation of excess lipids, resulting in the formation of foam cells in the skin or tendons. Typically, xanthomas are not accompanied by other symptoms. Here, we report a patient with a presentation of
Hyun Yi Lee, Dae Won Koo, Joong Sun Lee
doaj   +1 more source

Alternative cascade-testing protocols for identifying and managing patients with familial hypercholesterolaemia: systematic reviews, qualitative study and cost-effectiveness analysis

Health Technology Assessment, 2023
Background Cascade testing the relatives of people with familial hypercholesterolaemia is an efficient approach to identifying familial hypercholesterolaemia.
Nadeem Qureshi, Bethan Woods, Rita Neves de Faria, Pedro Saramago Goncalves, Edward Cox, Jo Leonardi-Bee, Laura Condon, Stephen Weng, Ralph K Akyea, Barbara Iyen, Paul Roderick, Steve E Humphries, William Rowlands, Melanie Watson, Kate Haralambos, Ryan Kenny, Dev Datta, Zosia Miedzybrodzka, Christopher Byrne, Joe Kai   +19 more
doaj   +1 more source

Familial Hyperlipoproteinemia Type II

Nishi Nihon Hifuka, 1974
両側肩甲部, 肘頭, 臀部, 下腿屈側, 膝蓋部, 第I, IV指間には扁平黄色腫, 両側手指基節部, 右アキレス腱部に結節性黄色腫を, 両手掌, 指腹部には腱に一致して縦に走る橙黄色の線条がみられ, その母, 兄, 姉にも扁平あるいは結節性黄色腫と高コレステロール血症がみられたfamilial hyperlipoproteinemia type IIと思われる21才, 女性例を報告した。なお血清脂質は, 総コレステロール484mg/dl, β-リポ蛋白1760mg/dl, 燐脂質450mg/dl, 遊離脂肪酸0.453mEq/l, トリグリセライト109mg/dlであつた。
MORISHITA, Reiko, TASHIRO, Masaaki
openaire   +1 more source