Results 41 to 50 of about 12,443,450 (160)

Molecular basis of familial chylomicronemia: mutations in the lipoprotein lipase and apolipoprotein C-II genes.

open access: yesJournal of Lipid Research, 1992
The molecular basis of familial chylomicronemia (type I hyperlipoproteinemia), a rare autosomal recessive trait, was investigated in six unrelated individuals (five of Spanish descent and one of Northern European extraction).
M Reina, JD Brunzell, SS Deeb
doaj   +1 more source

Graded Calorie Restriction Causes Graded Slowing of Epigenetic Ageing in Mice

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
Graded calorie restriction in male mice modified epigenetic signatures of the liver and slowed ageing rate in a graded manner. ABSTRACT DNA methylation variation is associated with chronological ageing. Calorie restriction (CR) prolongs lifespan and healthspan in many species.
Timothy P. Moulds   +6 more
wiley   +1 more source

Hyperlipoproteinemia in alcoholic subjects

open access: yes, 1973
Plasma lipid levels were tested in a group of a alcoholic patients admitted to an alcoholic ward. Triglycerides were significantly increased in comparison with a control population, most markedly in chronic alcoholics.
C.R. Sirtori   +2 more
core   +1 more source

A new method for the measurement of lipoprotein lipase in postheparin plasma using sodium dodecyl sulfate for the inactivation of hepatic triglyceride lipase.

open access: yesJournal of Lipid Research, 1979
Lipoprotein lipase (LPL) and hepatic triglyceride lipase (H-TGL) are lipolytic activities found in postheparin plasma. A simple and precise method for the direct determination of LPL in postheparin plasma is described.
M L Baginsky, W V Brown
doaj   +1 more source

Cellular Senescence, Inflammaging and Cardiovascular Disease

open access: yesImmunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Aging is the most important yet unmodifiable risk factor for cardiovascular disease (CVD). As a result, targeting cardiovascular aging has emerged as a promising strategy to promote long‐term cardiovascular health. This review summarizes current knowledge on the effects of aging within the cardiovascular system as well as systemic processes ...
Lukas Zanders   +3 more
wiley   +1 more source

Recurrent Pancreatitis Induced by Uncontrolled Type V Hyperlipoproteinemia

open access: yes, 2019
Background: Type V Hyperlipoproteinemia is a rare disease characterized by increased chylomicron and very low-density lipoprotein (VLDL) plasma levels. No official guidelines for treatment or monitoring of this disorder have been established due to the ...
Perez, Laura Oben   +3 more
core   +1 more source

Assessment of lipid metabolism in thyroid dysfunction

open access: yesZaporožskij Medicinskij Žurnal, 2014
1. Actuality According to WHO Thyroid dysfunction is one of the most prevalent in humans and is one of the risk factors of cardiovascular diseases. Hypothyroidism affects the mechanisms of potentiation of cardiovascular risk factors, suggesting the ...
V. G. Kadzharyan   +3 more
doaj   +1 more source

Genetic Insights on Hypertriglyceridaemia‐Induced Acute Pancreatitis in Pregnancy: A Case Series and Literature Review

open access: yesCase Reports in Endocrinology, Volume 2026, Issue 1, 2026.
Context Hypertriglyceridaemia‐induced pancreatitis in pregnancy (HTG‐IPP) is a rare but serious condition. There is a paucity of evidence‐based guidelines and recommendations for screening and management of HTG‐IPP. Individual genomics can predispose certain populations to a higher risk of developing HTG‐IPP. Objective To report on a case series of the
Christopher Son Nguyen   +5 more
wiley   +1 more source

The metabolism of low density lipoprotein in familial type II hyperlipoproteinemia [PDF]

open access: yesJournal of Clinical Investigation, 1972
The metabolism of low density lipoprotein (LDL, beta lipoprotein) was studied in 10 normal individuals and 10 patients with familial type II hyperlipoproteinemia using purified radioiodinated LDL. Over 97% of the label was bound to the protein moiety of LDL and therefore the turnover data reflect the fate and distribution of LDL-apoprotein.
T, Langer, W, Strober, R I, Levy
openaire   +2 more sources

Study of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Activity in Cultured Fibroblasts from Normal and Type II Hyperlipoproteinemic Individuals

open access: yes, 1974
vi, 31 p.The homozygous form of the autosomal dominant disease Type II hyperlipoproteinemia is characterized by elevated levels of cholesterol in the bloodstream.
Heinrich, Mary Beth
core   +1 more source

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