Results 41 to 50 of about 4,321 (203)

Graded Calorie Restriction Causes Graded Slowing of Epigenetic Ageing in Mice

Aging Cell, Volume 25, Issue 1, January 2026.
Graded calorie restriction in male mice modified epigenetic signatures of the liver and slowed ageing rate in a graded manner. ABSTRACT DNA methylation variation is associated with chronological ageing. Calorie restriction (CR) prolongs lifespan and healthspan in many species.
Timothy P. Moulds, Sharon E. Mitchell, Xiaojing Yang, Wei Guo, Emily Chen, Peter D. Adams, John R. Speakman   +6 more
wiley   +1 more source

Effect of changing dietary fat saturation on low-density lipoprotein metabolism in man [PDF]

, 1981
The mechanism of change in low-density lipoprotein (LDL) levels by diets differing in fat saturation have been studied. Turnover of 125I-LDL was measured in eight subjects with type II hyperlipoproteinemia and in seven normal control subjects during two ...
N. A. Le, W. V. Brown, J. D. Turner
core   +1 more source

Cellular Senescence, Inflammaging and Cardiovascular Disease

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Aging is the most important yet unmodifiable risk factor for cardiovascular disease (CVD). As a result, targeting cardiovascular aging has emerged as a promising strategy to promote long‐term cardiovascular health. This review summarizes current knowledge on the effects of aging within the cardiovascular system as well as systemic processes ...
Lukas Zanders, Denada Arifaj, Julian U. G. Wagner, Stefanie Dimmeler   +3 more
wiley   +1 more source

A Review of Plasma Lipids and Their Transport and a Study of Neonatal Familial Type II Hyperlipoproteinemia [PDF]

, 1970
v, 31 p.The general field of hyperlipoproteinemia has been recognized by scientists and doctors for a relatively short time. Even at the present time only people who live in large urban areas where this medical research is being carried on have ...
Dwyer, Rosalind
core  

Quantification of apolipoprotein E receptors in human brain-derived cell lines by real-time polymerase chain reaction [PDF]

, 2004
Apolipoprotein (apo) E4 is a risk factor for Alzheimer's disease (AD) and other neurodegenerative diseases, compared to wild-type apoE3. The mechanism(s) is unknown.
Owen, JS, Everett, D M, Murdock, P R, Everett, DM, Murdock, PR, Owen, J S, Dingwall, C, Thilakawardhana, S   +7 more
core   +1 more source

Isolation and characterization of an apoA-II-containing lipoprotein (LP-A-II:B complex) from plasma very low density lipoproteins of patients with Tangier disease and type V hyperlipoproteinemia.

Journal of Lipid Research, 1991
Previous studies have shown that very low density lipoproteins (VLDL) from patients with Tangier disease are less effective as a substrate for human milk lipoprotein lipase (LPL) than VLDL from normal controls as assessed by measuring the first order ...
P Alaupovic, C Knight-Gibson, CS Wang, D Downs, E Koren, HB Brewer, Jr, RE Gregg   +6 more
doaj   +1 more source

Genetic Insights on Hypertriglyceridaemia‐Induced Acute Pancreatitis in Pregnancy: A Case Series and Literature Review

Case Reports in Endocrinology, Volume 2026, Issue 1, 2026.
Context Hypertriglyceridaemia‐induced pancreatitis in pregnancy (HTG‐IPP) is a rare but serious condition. There is a paucity of evidence‐based guidelines and recommendations for screening and management of HTG‐IPP. Individual genomics can predispose certain populations to a higher risk of developing HTG‐IPP. Objective To report on a case series of the
Christopher Son Nguyen, Nicholas Adams, Emily Gianatti, I-Lynn Lee, Dev Kevat, Kalyani Sen   +5 more
wiley   +1 more source

Study of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Activity in Cultured Fibroblasts from Normal and Type II Hyperlipoproteinemic Individuals [PDF]

, 1974
vi, 31 p.The homozygous form of the autosomal dominant disease Type II hyperlipoproteinemia is characterized by elevated levels of cholesterol in the bloodstream.
Heinrich, Mary Beth
core  

Lipid-independent therapeutic properties of transdermal 17 B-estradiol on cardiovascular diseases. [PDF]

, 1992
A low dose of transdermally administered 17 B-estradiol promptly improved a severe, treatment-unresponsive, cardiac arrhythmia initiated after the menopause in a woman with type-II familial hyperlipoproteinemia.
Piero Fioretti, G. B. Melis, CAGNACCI A, PUCCINI E, R. Soldani, FIORETTI P, MELIS, GIAN BENEDETTO, Angelo Cagnacci, CAGNACCI, Angelo, Gian Benedetto Melis, E. Puccini, SOLDANI R, P. Fioretti, Enrico Puccini, Renza Soldani   +14 more
core   +1 more source

Putative Pathogenic Variants of ABCG5 and ABCG8 of Sitosterolemia in Patients With Hyper-Low-Density Lipoprotein Cholesterolemia

Journal of Lipid and Atherosclerosis
Objective Sitosterolemia is a rare autosomal recessive disease caused by the deleterious variants of adenosine 5'-triphosphate (ATP)-binding cassette sub-family G member 5 (ABCG5) or ATP-binding cassette sub-family G member 8 (ABCG8). There are only few
Nobuko Kojima, Hayato Tada, Akihiro Nomura, Soichiro Usui, Kenji Sakata, Kenshi Hayashi, Atsushi Nohara, Akihiro Inazu, Masa-aki Kawashiri, Masayuki Takamura   +9 more
doaj   +1 more source