Results 41 to 50 of about 6,562 (204)

Graded Calorie Restriction Causes Graded Slowing of Epigenetic Ageing in Mice

Aging Cell, Volume 25, Issue 1, January 2026.
Graded calorie restriction in male mice modified epigenetic signatures of the liver and slowed ageing rate in a graded manner. ABSTRACT DNA methylation variation is associated with chronological ageing. Calorie restriction (CR) prolongs lifespan and healthspan in many species.
Timothy P. Moulds, Sharon E. Mitchell, Xiaojing Yang, Wei Guo, Emily Chen, Peter D. Adams, John R. Speakman   +6 more
wiley   +1 more source

Assessment of lipid metabolism in thyroid dysfunction

Zaporožskij Medicinskij Žurnal, 2014
1. Actuality According to WHO Thyroid dysfunction is one of the most prevalent in humans and is one of the risk factors of cardiovascular diseases. Hypothyroidism affects the mechanisms of potentiation of cardiovascular risk factors, suggesting the ...
V. G. Kadzharyan, A. I. Melnik, P. P. Bidzilya, S. A. Solovyuk   +3 more
doaj   +1 more source

Recombinant gamma interferon induces hypertriglyceridemia and inhibits post-heparin lipase activity in cancer patients. [PDF]

, 1986
Animals suffering from malignancy or chronic infection develop characteristic metabolic abnormalities, including a well-defined hypertriglyceridemic state.
Bradley, WA, Gianturco, SH, Gutterman, JU, Kurzrock, R, Quesada, JR, Rohde, MF, Sherwin, SA   +6 more
core  

The Association Between Cardiovascular Risk and Elevated Triglycerides [PDF]

, 2017
BACKGROUND: The association between elevated triglycerides and cardiovascular risk has been extensively studied. The elevated level of triglycerides occurs through abnormalities in hepatic very low-density lipoprotein (VLDL) production and intestinal ...
Handayani, O. (Olivia), Sargowo, D. (Djanggan)   +1 more
core   +3 more sources

Cellular Senescence, Inflammaging and Cardiovascular Disease

Immunological Reviews, Volume 337, Issue 1, January 2026.
ABSTRACT Aging is the most important yet unmodifiable risk factor for cardiovascular disease (CVD). As a result, targeting cardiovascular aging has emerged as a promising strategy to promote long‐term cardiovascular health. This review summarizes current knowledge on the effects of aging within the cardiovascular system as well as systemic processes ...
Lukas Zanders, Denada Arifaj, Julian U. G. Wagner, Stefanie Dimmeler   +3 more
wiley   +1 more source

Effects of cholestyramine and chenodeoxycholic acid on the metabolism of endogenous triglyceride in hyperlipoproteinemia.

Journal of Lipid Research, 1978
Previous studies conducted under basal conditions have suggested a linkage between the formation of plasma triglyceride and the degradation of cholesterol to bile acids.
B Angelin, K Einarsson, K Hellström, B Leijd   +3 more
doaj   +1 more source

Animal models of NASH: getting both pathology and metabolic context right [PDF]

, 2015
Non-alcoholic fatty liver disease (NAFLD) is the most common cause of referral to liver clinics, and its progressive form, non-alcoholic steatohepatitis (NASH), can lead to cirrhosis and end-stage liver disease.
Larter, Claire Z., Yeh, Matthew M.
core   +1 more source

Genetic Insights on Hypertriglyceridaemia‐Induced Acute Pancreatitis in Pregnancy: A Case Series and Literature Review

Case Reports in Endocrinology, Volume 2026, Issue 1, 2026.
Context Hypertriglyceridaemia‐induced pancreatitis in pregnancy (HTG‐IPP) is a rare but serious condition. There is a paucity of evidence‐based guidelines and recommendations for screening and management of HTG‐IPP. Individual genomics can predispose certain populations to a higher risk of developing HTG‐IPP. Objective To report on a case series of the
Christopher Son Nguyen, Nicholas Adams, Emily Gianatti, I-Lynn Lee, Dev Kevat, Kalyani Sen   +5 more
wiley   +1 more source

Homozygous familial hypercholesterolemia: case report of a rare cause of dyslipidemia Homozygotyczna rodzinna hipercholesterolemia. Opis przypadku dotyczący rzadkich przyczyn dyslipidemii [PDF]

Pediatric Endocrinology, Diabetes and Metabolism, 2011
A 4-year-old boy was evaluated for severe hypercholesterolemia (cholesterol: 831 mg/dL) and disseminated xanthomas. Both parents had hypercholesterolemia: mother (cholesterol: 308 mg/dL) and father (cholesterol: 281 mg/dL). There was no family history of
Cresio Alves, Zilda Braid
doaj  

Peroxisome Proliferator-Activated Receptor alpha (PPAR alpha) down-regulation in cystic fibrosis lymphocytes [PDF]

, 2006
Background: PPARs exhibit anti-inflammatory capacities and are potential modulators of the inflammatory response. We hypothesized that their expression and/or function may be altered in cystic fibrosis (CF), a disorder characterized by an excessive host ...
C Hubeau, RB Moss, P Reineck, AA Ionescu, LS Nixon, ME Poynter, P Delerive, SW Chung, BM Forman, W Wahli, JD Tugwood, JM Shipley, A Madej, JP Despres, N Marx, B Staels, Z Israelian-Konaraki, A Trifilieff, MA Birrell, M Roulet, PM Farrell, AP Sampson, JT Zakrzewski, J Carlstedt-Duke, SD Freedman, SM Loitsch, KA Kreuzer, JL Su, JD Dignam, TP Dean, K Balough, TZ Khan, A Augarten, F Akbiyik, I Inoue, DC Jones, P Greally, E Dagli, TA Waldmann, JH Parmentier, K Beier, C Andersson, M Ollero, H Pall, G Chinetti, PR Devchand, N Marx, AE Lovett-Racke, A Linden, F McAllister, RB Moss, RB Moss, C Hubeau, RU Sorensen   +53 more
core   +1 more source