Results 61 to 70 of about 4,321 (203)
Türk Kardiyoloji Derneği Arşivi, 2014 Objectives: Familial hypercholesterolemia (FH) is a genetic disease characterized by extremely high levels of cholesterol leading to premature atherosclerosis. In homozygous individuals (HoFH) cardiovascular events could develop in child-hood.
Meral Kayıkçıoğlu +3 more
doaj +1 more source
The Role of Genetics in Stroke Risk and Outcome: A Review of Current Evidence
Brain and Behavior, Volume 15, Issue 10, October 2025.This study delineates the multiple pathways leading to stroke, encompassing genetic risk factors such as lipid/cholesterol metabolism, blood pressure regulation genes, and endothelial dysfunction. The report includes genetic pathways such as Val66Met polymorphism, prothrombin G20210A, interleukin‐6 and tumor necrosis factor gene variant, along with ...
Mega Obukohwo Oyovwi +3 more
wiley +1 more source
インスリン非依存型糖尿病にみられる血清リポ蛋白の変化とその機序に関する研究 [PDF]
, 1984 The classification of hyperlipoproteinemia observed in twenty-three noninsulin dependent type II diabetic patients who were not controlled well by diet and sulfonylurea was carried out.
Ozono, Noboru +3 more
core
Arquivos Brasileiros de CardiologiaBackground: Familial hypercholesterolemia (FH) is a common autosomal dominant disorder, characterized by a high level of low-density lipoprotein cholesterol (LDL-C) and a high risk of premature cardiovascular disease. Objective: To evaluate clinical and
Andrea De Lorenzo +4 more
doaj +1 more source
ESC Heart Failure, Volume 12, Issue 5, Page 3264-3275, October 2025.Abstract Aims In heart failure patients, altered myocardial electrical fields linked to oedema may impair left ventricular function. While short‐term use of implanted microcurrent generators (C‐MIC) has shown promise, long‐term effects remain unclear.
Dragana B. Kosevic +14 more
wiley +1 more source
ESC Heart Failure, Volume 12, Issue 5, Page 3655-3666, October 2025.Analysis of the usage of the HFA‐PEFF score‐based clinical decision support system (CDSS) and the main barriers and facilitators to its implementation, based on a survey of physicians. Abstract Background and aims Knowing that heart failure (HF) with preserved ejection fraction (HFpEF) can be difficult to diagnose, a clinical decision support system ...
Isidora Milosavljević +29 more
wiley +1 more source
Protective mechanisms against Alzheimer's disease in APOE3‐Christchurch homozygous astrocytes
Alzheimer's &Dementia, Volume 21, Issue 9, September 2025.Abstract INTRODUCTION Alzheimer's disease (AD) is characterized by tau pathology, leading to neurodegeneration. Astrocytes regulate central nervous system homeostasis and influence AD progression. The APOE3‐Christchurch (APOE3‐Ch) variant is linked to AD resilience, but its protective mechanisms remain unclear.
Xinran Tian +10 more
wiley +1 more source
A long-term study of the efficacy of oxandrolone in hyperlipoproteinemias [PDF]
, 1978 Oxandrolone, an anabolic steroid, significantly reduced serum triglycerides in type III, IV, and V hyperlipoproteinemia, with a concomitant decrease in pre-beta lipoproteins.
Van Den Bergen, C.J. +3 more
core +1 more source
Artificial Organs, Volume 49, Issue 8, Page 1346-1355, August 2025.Coronary artery revascularization with microaxial flow pump support in patients with severely reduced left ventricular ejection fraction is an emerging technique in cardiac surgery. In this manuscript, we present early results, highlight the advantages, and discuss the key limitations of this approach.
Gaik Nersesian +9 more
wiley +1 more source
Annals of Human Genetics, Volume 89, Issue 4, Page 208-227, July 2025.Abstract Introduction An ethics‐guided decision‐making framework was developed for applying pathology‐supported genetic testing, a multifaceted pharmacodiagnostic approach that translates population risk stratification into clinical utility. We introduce this service, supported by the Open Genome Project, which aligns with the beneficence principle in ...
Manie De Klerk +6 more
wiley +1 more source