Results 61 to 70 of about 772,552 (212)

Coronary Artery Bypass Grafting on Microaxial Flow Pump Support in Patients With Severely Reduced Left Ventricular Ejection Fraction

open access: yesArtificial Organs, Volume 49, Issue 8, Page 1346-1355, August 2025.
Coronary artery revascularization with microaxial flow pump support in patients with severely reduced left ventricular ejection fraction is an emerging technique in cardiac surgery. In this manuscript, we present early results, highlight the advantages, and discuss the key limitations of this approach.
Gaik Nersesian   +9 more
wiley   +1 more source

Incorporating familial risk, lifestyle factors, and pharmacogenomic insights into personalized noncommunicable disease (NCD) reports for healthcare funder beneficiaries participating in the Open Genome Project

open access: yesAnnals of Human Genetics, Volume 89, Issue 4, Page 208-227, July 2025.
Abstract Introduction An ethics‐guided decision‐making framework was developed for applying pathology‐supported genetic testing, a multifaceted pharmacodiagnostic approach that translates population risk stratification into clinical utility. We introduce this service, supported by the Open Genome Project, which aligns with the beneficence principle in ...
Manie De Klerk   +6 more
wiley   +1 more source

Clinical features, biomarker profiles, and neuroimaging characteristics in patients from memory clinic in china: The Shanghai Memory Study

open access: yesAlzheimer's &Dementia, Volume 21, Issue 6, June 2025.
Abstract INTRODUCTION Despite advances in biomarker assessment, molecular neuroimaging, and disease‐modifying therapies for cognitive disorders, China lacks well‐characterized clinical cohorts integrating comprehensive clinical assessments and multimodal biomarkers.
Jie Wang   +14 more
wiley   +1 more source

The effect of glucagon in various types of primary hyperlipoproteinemia

open access: yes, 1970
In order to further assess lipid-carbohydrate interactions in familial hyperlipoproteinemia, the acute and chronic effects of glucagon (3 mg i.m.) on plasma total cholesterol, triglycerides, non-esterified fatty acids and glucose were studied in 24 ...
Aubry, Francine
core  

Clinical evaluation of tibric acid (CP 18,524) a new hypolipidemic agent

open access: yes, 1974
Tibric Acid was given to thirteen volunteers (twelve patients with hyperlipoproteinemia and one normal subject) for a period of six months. The drug was well tolerated and it was effective in one daily administration of 500 mg in mild forms of ...
B. Quarisa, C.R. Sirtori, S. Zoppi
core   +1 more source

Effect of changing dietary fat saturation on low-density lipoprotein metabolism in man

open access: yes, 1981
The mechanism of change in low-density lipoprotein (LDL) levels by diets differing in fat saturation have been studied. Turnover of 125I-LDL was measured in eight subjects with type II hyperlipoproteinemia and in seven normal control subjects during two ...
N. A. Le, W. V. Brown, J. D. Turner
core   +1 more source

A Review of Plasma Lipids and Their Transport and a Study of Neonatal Familial Type II Hyperlipoproteinemia

open access: yes, 1970
v, 31 p.The general field of hyperlipoproteinemia has been recognized by scientists and doctors for a relatively short time. Even at the present time only people who live in large urban areas where this medical research is being carried on have ...
Dwyer, Rosalind
core  

Quantification of apolipoprotein E receptors in human brain-derived cell lines by real-time polymerase chain reaction

open access: yes, 2004
Apolipoprotein (apo) E4 is a risk factor for Alzheimer's disease (AD) and other neurodegenerative diseases, compared to wild-type apoE3. The mechanism(s) is unknown.
Owen, JS   +7 more
core   +1 more source

Yellow palms and feet in a child

open access: yesRussian Open Medical Journal, 2014
The yellowish discoloration of the palms and skin is reported under different terms: xanthodermia, hypercarotenemia, carotenemia, carotenodermia. Yellow discoloration of the skin may be associated with carotenemia, hypothyroidism, diabetes mellitus ...
Anca Chiriac   +5 more
doaj  

Study of 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Activity in Cultured Fibroblasts from Normal and Type II Hyperlipoproteinemic Individuals

open access: yes, 1974
vi, 31 p.The homozygous form of the autosomal dominant disease Type II hyperlipoproteinemia is characterized by elevated levels of cholesterol in the bloodstream.
Heinrich, Mary Beth
core  

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