Results 61 to 70 of about 11,928,997 (202)

The metabolism of low density lipoprotein in familial type II hyperlipoproteinemia [PDF]

open access: yesJournal of Clinical Investigation, 1972
The metabolism of low density lipoprotein (LDL, beta lipoprotein) was studied in 10 normal individuals and 10 patients with familial type II hyperlipoproteinemia using purified radioiodinated LDL. Over 97% of the label was bound to the protein moiety of LDL and therefore the turnover data reflect the fate and distribution of LDL-apoprotein.
T, Langer, W, Strober, R I, Levy
openaire   +2 more sources

Finerenone in diabetic chronic kidney disease—Real‐world insights including patients with HFpEF or HFmrEF

open access: yesESC Heart Failure, Volume 12, Issue 6, Page 4219-4229, December 2025.
Abstract Purpose Finerenone, a highly selective non‐steroidal mineralocorticoid receptor antagonist, was approved for the treatment of patients with chronic kidney disease (CKD) and type 2 diabetes mellitus (diabetic kidney disease, DKD). Finerenone reduced the composite endpoint of heart failure events and cardiovascular death in patients with heart ...
Kristian Hellenkamp   +9 more
wiley   +1 more source

Human type II hyperlipoproteinemia enhances platelet-collagen adhesion in flowing nonanticoagulated blood.

open access: yes, 1993
We investigated the effects of high plasma lipid levels on platelet adhesion and platelet thrombus formation in nonanticoagulated human blood on collagen fibrils at an arterial wall shear rate of 2600 seconds-1. Nonanticoagulated blood was drawn directly
A Diquélou   +6 more
core   +1 more source

Homozygous familial hypercholesterolemia: case report of a rare cause of dyslipidemia Homozygotyczna rodzinna hipercholesterolemia. Opis przypadku dotyczący rzadkich przyczyn dyslipidemii [PDF]

open access: yesPediatric Endocrinology, Diabetes and Metabolism, 2011
A 4-year-old boy was evaluated for severe hypercholesterolemia (cholesterol: 831 mg/dL) and disseminated xanthomas. Both parents had hypercholesterolemia: mother (cholesterol: 308 mg/dL) and father (cholesterol: 281 mg/dL). There was no family history of
Cresio Alves, Zilda Braid
doaj  

Assessment of lipid metabolism in thyroid dysfunction

open access: yesZaporožskij Medicinskij Žurnal, 2014
1. Actuality According to WHO Thyroid dysfunction is one of the most prevalent in humans and is one of the risk factors of cardiovascular diseases. Hypothyroidism affects the mechanisms of potentiation of cardiovascular risk factors, suggesting the ...
V. G. Kadzharyan   +3 more
doaj   +1 more source

Diagnostic Utility of Liver Biopsy in Persistent Unexplained Liver Enzyme Elevation: A Retrospective Cohort Study

open access: yesJGH Open, Volume 9, Issue 11, November 2025.
ABSTRACT Background and Aims Chronically elevated liver enzymes without a clear etiology remain a frequent diagnostic challenge. This study evaluated the diagnostic yield of liver biopsy in such cases and assessed if laboratory parameters predict histological clarification. Methods We retrospectively analyzed 71 patients with unexplained elevated liver
S. Jaawan   +8 more
wiley   +1 more source

Beyond lipids: Systemic effects of lipoprotein apheresis

open access: yes
Transfusion, Volume 66, Issue 3, Page 590-598, March 2026.
Menatalla Nadim, Yamac Akgun
wiley   +1 more source

Hyperlipoproteinemia in alcoholic subjects

open access: yes, 1973
Plasma lipid levels were tested in a group of a alcoholic patients admitted to an alcoholic ward. Triglycerides were significantly increased in comparison with a control population, most markedly in chronic alcoholics.
C.R. Sirtori   +2 more
core   +1 more source

Long-term follow-up in patients with homozygous familial hypercholesterolemia; 13-year experience of a university hospital lipid clinic

open access: yesTürk Kardiyoloji Derneği Arşivi, 2014
Objectives: Familial hypercholesterolemia (FH) is a genetic disease characterized by extremely high levels of cholesterol leading to premature atherosclerosis. In homozygous individuals (HoFH) cardiovascular events could develop in child-hood.
Meral Kayıkçıoğlu   +3 more
doaj   +1 more source

The Role of Genetics in Stroke Risk and Outcome: A Review of Current Evidence

open access: yesBrain and Behavior, Volume 15, Issue 10, October 2025.
This study delineates the multiple pathways leading to stroke, encompassing genetic risk factors such as lipid/cholesterol metabolism, blood pressure regulation genes, and endothelial dysfunction. The report includes genetic pathways such as Val66Met polymorphism, prothrombin G20210A, interleukin‐6 and tumor necrosis factor gene variant, along with ...
Mega Obukohwo Oyovwi   +3 more
wiley   +1 more source

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