Results 61 to 70 of about 6,562 (204)

Protective mechanisms against Alzheimer's disease in APOE3‐Christchurch homozygous astrocytes

Alzheimer's &Dementia, Volume 21, Issue 9, September 2025.
Abstract INTRODUCTION Alzheimer's disease (AD) is characterized by tau pathology, leading to neurodegeneration. Astrocytes regulate central nervous system homeostasis and influence AD progression. The APOE3‐Christchurch (APOE3‐Ch) variant is linked to AD resilience, but its protective mechanisms remain unclear.
Xinran Tian, Erica Keane Rivera, Inyoung Hwang, Arina A. Nikitina, Jennifer A. Smith, Youngsuh J. Cho, Julia Sala‐Jarque, Austin DuBose, Clare Andriola, Toby Gollan‐Myers, Kenneth S. Kosik   +10 more
wiley   +1 more source

Low-density lipoprotein receptor-deficient mice are protected against lethal endotoxemia and severe gram-negative infections [PDF]

, 1996
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Netea, M.G., Demacker, P.N.M., Kullberg, B.J., Boerman, O.C., Verschueren, I., Stalenhoef, A.F.H., Meer, J.W.M. van der   +6 more
core   +1 more source

Métabolisme lipidique et hyperlipémies chez le chien [PDF]

, 2004
peer reviewedaudience: researcher, professionalThis synthesis aims to summarize lipids metabolism in the dog. The different aetiology and diagnostic of primary or secondary hyperlipidaemia in dog are reviewed.
Diez, Marianne, Istasse, Louis, Jeusette, Isabelle   +2 more
core  

A Cross-Sectional Study of Prisoners in Mexico City Comparing Prevalence of Transmissible Infections and Chronic Diseases with That in the General Population. [PDF]

, 2015
ObjectivesTo describe patterns of transmissible infections, chronic illnesses, socio-demographic characteristics and risk behaviors in Mexico City prisons, including in comparison to the general population, to identify those currently needing healthcare ...
Bautista-Arredondo, Sergio, Bertozzi, Stefano M, Beynon, Fenella, Conde-Glez, Carlos J, González, Andrea, Gras, Nathalie, Juarez-Figueroa, Luis, Lopez-Ridaura, Ruy, Servan-Mori, Edson, Sierra-Madero, Juan, Volkow, Patricia   +10 more
core   +3 more sources

Incorporating familial risk, lifestyle factors, and pharmacogenomic insights into personalized noncommunicable disease (NCD) reports for healthcare funder beneficiaries participating in the Open Genome Project

Annals of Human Genetics, Volume 89, Issue 4, Page 208-227, July 2025.
Abstract Introduction An ethics‐guided decision‐making framework was developed for applying pathology‐supported genetic testing, a multifaceted pharmacodiagnostic approach that translates population risk stratification into clinical utility. We introduce this service, supported by the Open Genome Project, which aligns with the beneficence principle in ...
Manie De Klerk, Nicole Van Der Merwe, Johny Erasmus, Lindiwe Whati, Kelebogile E. Moremi, Daniel W. Olivier, Maritha J. Kotze   +6 more
wiley   +1 more source

Low-density lipoprotein size and cardiovascular risk assessment [PDF]

, 2017
A predominance of small, dense low-density lipoproteins (LDL) has been accepted as an emerging cardiovascular risk factor by the National Cholesterol Education Program Adult Treatment Panel III.
Berneis, K., Rizzo, M.
core  

Clinical features, biomarker profiles, and neuroimaging characteristics in patients from memory clinic in china: The Shanghai Memory Study

Alzheimer's &Dementia, Volume 21, Issue 6, June 2025.
Abstract INTRODUCTION Despite advances in biomarker assessment, molecular neuroimaging, and disease‐modifying therapies for cognitive disorders, China lacks well‐characterized clinical cohorts integrating comprehensive clinical assessments and multimodal biomarkers.
Jie Wang, Xiaoxi Ma, Jiaying Lu, Jie Wu, Zhenxu Xiao, Huiwei Zhang, Weiqi Bao, Saineng Ding, Li Zheng, Xiaoniu Liang, Yihui Guan, Chuantao Zuo, Ding Ding, Qianhua Zhao, the Shanghai Memory Study (SMS)   +14 more
wiley   +1 more source

Association of Cardiovascular Biomarkers With Cardiac Allograft Vasculopathy and Atherosclerotic Coronary Artery Disease

Clinical Transplantation, Volume 39, Issue 6, June 2025.
ABSTRACT Background: Cardiac allograft vasculopathy (CAV) remains a barrier to long‐term survival after heart transplantation. Little is known about cardiovascular biomarkers in CAV and how they compare to biomarkers in atherosclerotic coronary artery disease (CAD).
Lukas Köster, Jessica Weimann, Alexander Bernhard, Benjamin Bay, Christopher M. Blaum, Thiess Lorenz, Tanja Zeller, Christoph Waldeyer, Hermann Reichenspurner, Paulus Kirchhof, Stefan Blankenberg, Christina Magnussen, Fabian J. Brunner   +12 more
wiley   +1 more source

Yellow palms and feet in a child

Russian Open Medical Journal, 2014
The yellowish discoloration of the palms and skin is reported under different terms: xanthodermia, hypercarotenemia, carotenemia, carotenodermia. Yellow discoloration of the skin may be associated with carotenemia, hypothyroidism, diabetes mellitus ...
Anca Chiriac, Anca E. Chiriac, Tudor Pinteala, Elena Gologan, Caius Solovan, Piotr Brzezinski   +5 more
doaj  

Portacaval Shunt and Hyperlipidemia [PDF]

, 1978
The use of a completely diverting portacaval shunt for the purpose of lowering the serum concentration of cholesterol and low-density lipoproteins is reviewed and a recommendation provided that such a shunt for hyperlipidemia should be considered for ...
Koep, LJ, Putnam, CW, Starzl, TE
core   +1 more source