Results 51 to 60 of about 6,562 (204)

Impact of epicardial adipose tissue on myocardial function and structure in patients with severe aortic valve stenosis

ESC Heart Failure, Volume 12, Issue 6, Page 4230-4241, December 2025.
Epicardial adipose tissue (EAT) has been linked to adverse remodelling and outcomes in aortic valve stenosis (AS), yet mechanisms remain unclear. In 137 patients with severe AS undergoing CMR before TAVR, higher EAT (≥46.5 ml/m2) was associated with impaired left atrial (LA) reservoir strain, while ventricular morphology, function and tissue ...
Judith Gronwald, Torben Lange, Sören J. Backhaus, Bo E. Beuthner, Ruben Evertz, Miriam Puls, Johannes T. Kowallick, Karl Toischer, Gerd Hasenfuß, Andreas Schuster, Alexander Schulz   +10 more
wiley   +1 more source

Long-term follow-up in patients with homozygous familial hypercholesterolemia; 13-year experience of a university hospital lipid clinic

Türk Kardiyoloji Derneği Arşivi, 2014
Objectives: Familial hypercholesterolemia (FH) is a genetic disease characterized by extremely high levels of cholesterol leading to premature atherosclerosis. In homozygous individuals (HoFH) cardiovascular events could develop in child-hood.
Meral Kayıkçıoğlu, Erkan Kısmalı, Levent Can, Serdar Payzin   +3 more
doaj   +1 more source

Chronic small vessel disease affects clinical outcome in patients with acute striatocapsular stroke [PDF]

, 2011
Background: Recovery from stroke is presumed to be a function of a cerebral network. Chronic small vessel disease (SVD) has been shown to disrupt this network’s integrity and has been proposed as a predictor of poor outcome after stroke.
Bäzner, Hansjörg, Held, Valentin, Hennerici, Michael G., Szabo, Kristina   +3 more
core   +1 more source

Finerenone in diabetic chronic kidney disease—Real‐world insights including patients with HFpEF or HFmrEF

ESC Heart Failure, Volume 12, Issue 6, Page 4219-4229, December 2025.
Abstract Purpose Finerenone, a highly selective non‐steroidal mineralocorticoid receptor antagonist, was approved for the treatment of patients with chronic kidney disease (CKD) and type 2 diabetes mellitus (diabetic kidney disease, DKD). Finerenone reduced the composite endpoint of heart failure events and cardiovascular death in patients with heart ...
Kristian Hellenkamp, Sophia Kaebe, Miroslava Valentova, Stephan von Haehling, Fani Delistefani, Katja Gollisch, Dirk Raddatz, Ann‐Kathrin Schäfer, Michael J. Koziolek, Manuel Wallbach   +9 more
wiley   +1 more source

Clinical, Anthropometric and Biochemical Characteristics of Patients with or without Genetically Confirmed Familial Hypercholesterolemia

Arquivos Brasileiros de Cardiologia
Background: Familial hypercholesterolemia (FH) is a common autosomal dominant disorder, characterized by a high level of low-density lipoprotein cholesterol (LDL-C) and a high risk of premature cardiovascular disease. Objective: To evaluate clinical and
Andrea De Lorenzo, Juliana Duarte Lopes da Silva, Cinthia E. James, Alexandre C. Pereira, Annie Seixas Bello Moreira   +4 more
doaj   +1 more source

Lipoprotein metabolism in nonalcoholic fatty liver disease [PDF]

, 2013
Nonalcoholic fatty liver disease (NAFLD), an escalating health problem worldwide, covers a spectrum of pathologies characterized by fatty accumulation in hepatocytes in early stages, with potential progression to liver inflammation, fibrosis, and failure.
Jiang, Zhenghui Gordon, Robson, Simon Christopher, Yao, Zemin   +2 more
core   +1 more source

Beyond lipids: Systemic effects of lipoprotein apheresis

Transfusion, Volume 66, Issue 3, Page 590-598, March 2026.
Menatalla Nadim, Yamac Akgun
wiley   +1 more source

The Role of Genetics in Stroke Risk and Outcome: A Review of Current Evidence

Brain and Behavior, Volume 15, Issue 10, October 2025.
This study delineates the multiple pathways leading to stroke, encompassing genetic risk factors such as lipid/cholesterol metabolism, blood pressure regulation genes, and endothelial dysfunction. The report includes genetic pathways such as Val66Met polymorphism, prothrombin G20210A, interleukin‐6 and tumor necrosis factor gene variant, along with ...
Mega Obukohwo Oyovwi, Benneth Ben‐Azu, Ejayeta Jeroh, Faith B. Friday   +3 more
wiley   +1 more source

Two‐year outcomes of a cardiac microcurrent device in chronic heart failure: A first‐in‐human pilot study

ESC Heart Failure, Volume 12, Issue 5, Page 3264-3275, October 2025.
Abstract Aims In heart failure patients, altered myocardial electrical fields linked to oedema may impair left ventricular function. While short‐term use of implanted microcurrent generators (C‐MIC) has shown promise, long‐term effects remain unclear.
Dragana B. Kosevic, Una Radak, Petar Vukovic, Jan D. Schmitto, Kersten Brandes, Peter Goettel, Hans‐Dirk Duengen, Elvis Tahirovic, Marija Zdravkovic, Johannes Mueller, Faouzi Kallel, Marat Fudim, Stefan D. Anker, Jesus Eduardo Rame, Miodrag Peric   +14 more
wiley   +1 more source

Facilitators, barriers, and insights using an HFA‐PEFF‐based clinical decision support system: A proof‐of‐concept study

ESC Heart Failure, Volume 12, Issue 5, Page 3655-3666, October 2025.
Analysis of the usage of the HFA‐PEFF score‐based clinical decision support system (CDSS) and the main barriers and facilitators to its implementation, based on a survey of physicians. Abstract Background and aims Knowing that heart failure (HF) with preserved ejection fraction (HFpEF) can be difficult to diagnose, a clinical decision support system ...
Isidora Milosavljević, Ivan Petrović, Aleksandra Ilić, Dragana Dabović, Aleksandra Milovančev, Goran Remer, Vladimir Vuković, Dimitrije Zdravković, Maja Stefanović, Snežana Stojšić, Ana Balenović, Goran Lončar, Snežana Tadić, Milana Jaraković, Snežana Bjelić, Snežana Čemerlić, Marija Bjelobrk, Tatjana Miljković, Andrej Preveden, Milovan Petrović, Srdjan Maletin, Tanja Popov, Vanja Drljević Todić, Mirko Todić, Aleksandra Vulin, Milenko Čanković, Dragica Andrić, Dragoslava Živkov Šaponja, Aleksandar Redžek, Anastazija Stojšić Milosavljević   +29 more
wiley   +1 more source