Results 31 to 40 of about 12,443,450 (160)

Alteration in oral and non‐oral tissues in ligature‐induced periodontitis mice with the Alzheimer's disease risk factor APOE4

European Journal of Oral Sciences, Volume 134, Issue 4, August 2026.
Abstract The APOE4 gene, particularly the ε4 allele, is linked to susceptibility to Alzheimer's disease, and periodontitis can cause pathological changes in multiple organs, but combined effects of these conditions and the impact of tumor necrosis factor (TNF)‐α regulation on the combined effects remain unclear.
Ae Ri Kim, Yun‐Jung Yoo, Eun‐Jung Bak   +2 more
wiley   +1 more source

A Novel APOC2 Mutation in a Colombian Patient with Recurrent Hypertriglyceridemic Pancreatitis

The Application of Clinical Genetics, 2020
Gabriel D Pinilla-Monsalve,1,* Juliana Lores,1,2,* Harry Pachajoa,1,2 Juan D López-Ponce de León,1,3 Alejandro López,1,4 Lisa X Rodríguez-Rojas,1,2 José A Nastasi-Catanese1,2 1Faculty of Health Sciences, Universidad ...
Pinilla-Monsalve GD, Lores J, Pachajoa H, López-Ponce de León JD, López A, Rodríguez-Rojas LX, Nastasi-Catanese JA   +6 more
doaj  

Quantitation of human apolipoprotein C-III and its subspecie by radioimmunoassay and analytical isoelectric focusing: abnormal plasma triglyceride-rich lipoprotein apolipoprotein C-III subspecie concentrations in hypertriglyceridemia.

Journal of Lipid Research, 1981
A specific, accurate, and sensitive double antibody radioimmunoassay for measuring human apolipoprotein (apo) C-III has been developed. Anti-apoC-III(1) developed in rabbits cross-reacted completely with apoC-III subspecies.
M L Kashyap, L S Srivastava, B A Hynd, P S Gartside, G Perisutti   +4 more
doaj   +1 more source

How does type 2 diabetes modify the risk of Alzheimer's disease?

Alzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract Type 2 diabetes (T2D) and Alzheimer's disease (AD) are both increasing exponentially worldwide. T2D has also been identified as one of 14 modifiable risk factors for dementia, but the mechanism is unknown. T2D could promote dementia via vascular or AD neuropathological changes, and mechanistic hypotheses include central insulin resistance and ...
G. T. Sutherland, A. Chen, H‐T. Nguyen‐Hao, H. Mundell, E. Aladyeva, M. J. Hofer, O. Harari, S. M. Twigg   +7 more
wiley   +1 more source

A Case of Eruptive Xanthoma Associated with Type IV Hyperlipoproteinemia and Koebner Phenomenon [PDF]

, 2008
Type IV hyperlipoproteinemia is characterized by increased blood levels of the triglyceride form of the fat that makes up very low-density lipoproteins (VLDL).
이주희, 이광훈
core  

Molecular analysis of three known and one novel LPL variants in patients with type I hyperlipoproteinemia [PDF]

, 2018
Background and aims: Type I hyperlipoproteinemia, also known as familial chylomicronemia syndrome (FCS), is a rare autosomal recessive disorder caused by variants in LPL, APOC2, APOA5, LMF1 or GPIHBP1 genes.
Sandstedt J., Russo C., Maurotti S., Caddeo A., Pirazzi C., Sasidharan K., Romeo S., Montalcini T., Leren T. P., Pingitore P., Pujia A., Mancina R. M., Leren, T. P., Pujia, A., S. Romeo, S. Maurotti, Sandstedt, J, C. Russo, Mancina, Rosellina Margherita,, Romeo, Stefano,, R.M. Mancina, Caddeo, Andrea,, Montalcini, T., T.P. Leren, Pingitore, Piero,, A. Caddeo, T. Montalcini, Russo, C., K. Sasidharan, J. Sandstedt, A. Pujia, Sasidharan, Kavitha,, C. Pirazzi, P. Pingitore, Pirazzi, Carlo,, Maurotti, S.   +35 more
core   +2 more sources

Milky Plasma, Murky Diagnosis: Urgent Plasma Exchange for Severe Hypertriglyceridemia‐Induced Hyperviscosity Without Pancreatitis, but With Myocardial Infarction

Journal of Clinical Apheresis, Volume 41, Issue 1, February 2026.
ABSTRACT Severe hypertriglyceridemia can increase the risk of acute pancreatitis, but also clinically significant hyperviscosity syndrome characterized by the typical signs of neurologic and visual manifestations. Hyperviscosity syndrome is a well‐established medical emergency.
Catherine Bodnar, Christina Hughey, Ariel Bodker, Chinelo P. Onyenekwu   +3 more
wiley   +1 more source

Isolation and characterization of an apoA-II-containing lipoprotein (LP-A-II:B complex) from plasma very low density lipoproteins of patients with Tangier disease and type V hyperlipoproteinemia.

Journal of Lipid Research, 1991
Previous studies have shown that very low density lipoproteins (VLDL) from patients with Tangier disease are less effective as a substrate for human milk lipoprotein lipase (LPL) than VLDL from normal controls as assessed by measuring the first order ...
P Alaupovic, C Knight-Gibson, CS Wang, D Downs, E Koren, HB Brewer, Jr, RE Gregg   +6 more
doaj   +1 more source

Inference About Separable Causal Effects With Longitudinal Bivariate Ordinal Responses With Missingness and Censoring

Statistics in Medicine, Volume 45, Issue 3-5, February 2026.
ABSTRACT Causal inference has gained extensive attention in various fields, including healthcare, epidemiology, and social sciences. While many methods have been developed, most research has been directed to handle data with a univariate response variable.
Pingbo Hu, Grace Y. Yi
wiley   +1 more source

Putative Pathogenic Variants of ABCG5 and ABCG8 of Sitosterolemia in Patients With Hyper-Low-Density Lipoprotein Cholesterolemia

Journal of Lipid and Atherosclerosis
Objective Sitosterolemia is a rare autosomal recessive disease caused by the deleterious variants of adenosine 5'-triphosphate (ATP)-binding cassette sub-family G member 5 (ABCG5) or ATP-binding cassette sub-family G member 8 (ABCG8). There are only few
Nobuko Kojima, Hayato Tada, Akihiro Nomura, Soichiro Usui, Kenji Sakata, Kenshi Hayashi, Atsushi Nohara, Akihiro Inazu, Masa-aki Kawashiri, Masayuki Takamura   +9 more
doaj   +1 more source