Results 21 to 30 of about 4,321 (203)

Control of sterol synthesis and of hydroxymethylglutaryl CoA reductase in skin fibroblasts grown from patients with homozygous type II hyperlipoproteinemia

open access: yesJournal of Lipid Research, 1975
In skin fibroblasts grown from four children with a homozygous form of type II hyperlipoproteinemia, the feedback control of sterol synthesis and the inhibitory effect on hydroxymethylglutaryl (HMG) CoA reductase activity by serum or low density ...
J. Avigan, S.J. Bhathena, M.E. Schreiner
doaj   +1 more source

A case report of palmar xanthoma with xanthomatous neuropathy

open access: yesSAGE Open Medical Case Reports, 2021
Xanthomas are plaques or nodules consisting of an accumulation of excess lipids, resulting in the formation of foam cells in the skin or tendons. Typically, xanthomas are not accompanied by other symptoms. Here, we report a patient with a presentation of
Hyun Yi Lee, Dae Won Koo, Joong Sun Lee
doaj   +1 more source

Phenotyping of type II and IV hyperlipoproteinemias by a simple, quantitative agarose gel lipoprotein electrophoresis [PDF]

open access: yes, 1971
From the statistical analysis of the densitometric percentage counts derived from 97 lipoprotein electrophoreses from patients with Type II or Type IV hyperlipoproteinemia, we developed a simple sequential screening approach.
R. Hassanein   +3 more
core   +1 more source

Fibrinogen catabolism in patients with type II and type IV hyperlipidemia. Effect of dietary and clofibrate treatment on laboratory findings. [PDF]

open access: yes, 1981
Fibrinogen catabolism was studied by plasma fibrinogen chromatography and other methods in 99 subjects with hyperlipoproteinemia Types IIa, IIb, and IV, and in 24 control subjects with normal blood lipid values.
G Schonfeld   +3 more
core   +1 more source

Normalization of plasma lipoprotein concentrations in patients with type II hyperlipoproteinemia by combined use of neomycin and niacin. [PDF]

open access: yes, 1984
The oral administration of neomycin or niacin as single-drug therapy can significantly lower total and low-density lipoprotein cholesterol concentrations in patients with type II hyperlipoproteinemia. However, in the majority of patients treated with one
D L Sprecher   +9 more
core   +1 more source

Alternative cascade-testing protocols for identifying and managing patients with familial hypercholesterolaemia: systematic reviews, qualitative study and cost-effectiveness analysis

open access: yesHealth Technology Assessment, 2023
Background Cascade testing the relatives of people with familial hypercholesterolaemia is an efficient approach to identifying familial hypercholesterolaemia.
Nadeem Qureshi   +19 more
doaj   +1 more source

Familial Hyperlipoproteinemia Type II

open access: yesNishi Nihon Hifuka, 1974
両側肩甲部, 肘頭, 臀部, 下腿屈側, 膝蓋部, 第I, IV指間には扁平黄色腫, 両側手指基節部, 右アキレス腱部に結節性黄色腫を, 両手掌, 指腹部には腱に一致して縦に走る橙黄色の線条がみられ, その母, 兄, 姉にも扁平あるいは結節性黄色腫と高コレステロール血症がみられたfamilial hyperlipoproteinemia type IIと思われる21才, 女性例を報告した。なお血清脂質は, 総コレステロール484mg/dl, β-リポ蛋白1760mg/dl, 燐脂質450mg/dl, 遊離脂肪酸0.453mEq/l, トリグリセライト109mg/dlであつた。
MORISHITA, Reiko, TASHIRO, Masaaki
openaire   +1 more source

Identification of an apoC-II variant (apoC-IIBethesda) in a kindred with apoC-II deficiency and type I hyperlipoproteinemia.

open access: yesJournal of Lipid Research, 1988
Apolipoprotein (apo) C-II deficiency is characterized by elevated plasma triglycerides, chylomicrons, and very low density lipoproteins, as well as reduced levels of low density and high density lipoproteins.
D L Sprecher   +6 more
doaj   +1 more source

Effects of therapy with cholestyramine on progression of coronary arteriosclerosis: results of the NHLBI Type II Coronary Intervention Study. [PDF]

open access: yes, 1984
In the National Heart, Lung and Blood Institute Type II Coronary Intervention Study, patients with Type II hyperlipoproteinemia and coronary artery disease (CAD) were placed on a low-fat, low-cholesterol diet and then were randomly allocated to receive ...
R I Levy   +9 more
core   +1 more source

Pathogenesis of type III hyperlipoproteinemia (dysbetalipoproteinemia): questions, quandaries, and paradoxes

open access: yesJournal of Lipid Research, 1999
Type III hyperlipoproteinemia (HLP) is a genetic disorder characterized by accumulation of remnant lipoproteins in the plasma and development of premature atherosclerosis. Although receptor binding-defective forms of apolipoprotein (apo) E are the common
Robert W. Mahley   +2 more
doaj   +1 more source

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