Plasma lipoprotein metabolism in transgenic mice overexpressing apolipoprotein E. Accelerated clearance of lipoproteins containing apolipoprotein B. [PDF]
, 1992 We have reported that transgenic mice overexpressing rat apo E shows marked reduction of plasma cholesterol and triglyceride levels due to the disappearance of VLDL and LDL.
Gotoda Takanari +8 more
core +1 more source
The 1(st) and the 2(nd) Italian Consensus Conferences on low-density lipoprotein-apheresis. A practical synopsis and update [PDF]
, 2016 The clinical indications and guidelines for low-density lipoprotein (LDL)-apheresis set by the 1(st) Italian Consensus Conference held in Ostuni in 1990 and completed in 1992, but never published, are reported schematically.
Stefanutti, Claudia
core +1 more source
Pathophysiology of elevated ascites fluid cholesterol in malignant ascites [PDF]
, 1992 The existence of marked elevations of ascitic fluid cholesterol has been observed in patients with peritoneal carcinomatosis compared to patients with cirrhosis and has been found useful in differential diagnosis.
Alexander L. Gerbes +27 more
core +1 more source
Blood rheology, cardiovascular risk factors, and cardiovascular disease: The West of Scotland Coronary Prevention Study [PDF]
, 2000 The West of Scotland Coronary Prevention Study (WOSCOPS) showed that pravastatin reduced the risk of coronary heart disease (CHD) events in 6,595 middle-aged hypercholesterolaemic men aged 45-64 years without prior myocardial infarction followed for an ...
Ann Rumley +8 more
core +1 more source
Low-Density Lipoprotein (LDL)-Antioxidant Biflavonoids from Garcinia madruno [PDF]
Molecules, 2013 Six biflavonoids were isolated from G. madruno, one of which, 7''-O-(6''''-acetyl)-glucoside of morelloflavone, is a new compound identified on the basis of 1D, 2D NMR (HMQC and HMBC) spectroscopic methods and chemical evidence. The antioxidant activity of the biflavonoids against low-density lipoprotein (LDL) peroxidation induced with Cu2+, was ...
Osorio Durango, Edinson +2 more
openaire +6 more sources
Differential Effects of Lipid-lowering Drugs in Modulating Morphology of Cholesterol Particles. [PDF]
, 2017 Treatment of dyslipidemia patients with lipid-lowering drugs leads to a significant reduction in low-density lipoproteins (LDL) level and a low to moderate level of increase in high-density lipoprotein (HDL) cholesterol in plasma.
Alderete, Benjamin +7 more
core +1 more source
Effect of a novel nutraceutical combination on serum lipoprotein functional profile and circulating PCSK9 [PDF]
, 2017 BACKGROUND: A beneficial effect on cardiovascular risk may be obtained by improving lipid-related serum lipoprotein functions such as high-density lipoproteins (HDLs) cholesterol efflux capacity (CEC) and serum cholesterol loading capacity (CLC) and by ...
Adorni, Maria Pia +7 more
core +3 more sources
Maternal obesity is associated with the formation of small dense LDL and hypoadiponectinemia in the third trimester [PDF]
, 2013 Context: Maternal obesity is associated with high plasma triglyceride, poor vascular function, and an increased risk for pregnancy complications. In normal-weight pregnant women, higher triglyceride is associated with increased small, dense low-density ...
Brown, E.A. +9 more
core +2 more sources
Anti-inflammatory and antioxidant properties of HDLs are impaired in type 2 diabetes. [PDF]
, 2011 ObjectiveIn mice, 4F, an apolipoprotein A-I mimetic peptide that restores HDL function, prevents diabetes-induced atherosclerosis. We sought to determine whether HDL function is impaired in type 2 diabetic (T2D) patients and whether 4F treatment improves
Boldrini, Beatrice +7 more
core +1 more source
Dietary fatty acids and lipoproteins on progression of age-related macular degeneration [PDF]
, 2017 Age-related macular degeneration (AMD) is a medical condition of central loss vision and blindness. Numerous studies have revealed that changes on certain dietary fatty acids (FAs) could have useful for AMD management.
Abia González, María del Rocío +5 more
core +3 more sources