Results 21 to 30 of about 523,270 (314)

Lipids and Lipoproteins in Health and Disease: Focus on Targeting Atherosclerosis

Biomedicines, 2021
Despite advances in pharmacotherapy, intervention devices and techniques, residual cardiovascular risks still cause a large burden on public health. Whilst most guidelines encourage achieving target levels of specific lipids and lipoproteins to reduce ...
Chih-Kuo Lee, Che-Wei Liao, Shih-Wei Meng, Wei-Kai Wu, Jiun-Yang Chiang, Ming-Shiang Wu   +5 more
doaj   +1 more source

Lipoprotein(a): A New Intensive Care Unit Admission Predictor in Coronavirus Disease 2019 Patients [PDF]

, 2023
OBJECTIVE: Endothelium-related events in patients with coronavirus disease 2019 are linked to a poor prognosis. Lipoprotein(a) plays a role in vascular endothelial cell dysfunction.
Alkan, Sevil, Bahadir Kirilmaz, Akşit, Ercan, Ercan Aksit, Şener, Alper, Alper Sener, Servan Vurucu, Küçük, Uğur, Ugur Kucuk, Bahadır Kırılmaz, Kırılmaz, Bahadır, Sevil Alkan, Vurucu, Servan   +12 more
core   +1 more source

Dietary fish oil enriched in very-long-chain polyunsaturated fatty acid reduces cardiometabolic risk factors and improves retinal function

iScience, 2023
Summary: Very-long-chain polyunsaturated fatty acids (VLCPUFAs; C24-38) constitute a unique class of PUFA that have important biological roles, but the lack of a suitable dietary source has limited research in this field.
Zhi-Hong Yang, Aruna Gorusupudi, Todd A. Lydic, Anupam K. Mondal, Seizo Sato, Isao Yamazaki, Hideaki Yamaguchi, Jingrong Tang, Krishna Vamsi Rojulpote, Anna B. Lin, Hannah Decot, Hannah Koch, Daniel C. Brock, Ranganathan Arunkumar, Zhen-Dan Shi, Zu-Xi Yu, Milton Pryor, Julia F. Kun, Rolf E. Swenson, Anand Swaroop, Paul S. Bernstein, Alan T. Remaley   +21 more
doaj   +1 more source

Lipoprotein apheresis to treat elevated lipoprotein (a) [PDF]

Journal of Lipid Research, 2016
An elevated plasma concentration of lipoprotein (a) [Lp(a)] is an independent risk factor for cardiovascular disease. Life style modification and currently available drugs either fail to effectively lower plasma Lp(a) levels or do not result in clinical benefit. However, lipoprotein apheresis is very efficient in decreasing Lp(a) concentrations.
Elisa, Waldmann, Klaus G, Parhofer
openaire   +2 more sources

HIV infection significantly reduces lipoprotein lipase which remains low after 6 months of antiretroviral therapy [PDF]

, 2008
Purpose of the study Fractional clearance rate of apolipoprotein B100-containing lipoproteins is reduced in HIV infection before and after antiretroviral (ARV) treatment [1].
LL Gathercole, M Boothby, S Das, Gathercole, L. L., McGee, K. C. (Kirsty Claire), Tomlinson, Jeremy, Shojaee-Moradie, F, Das, S. (Satyajit), Umpleby, AM, Tomlinson, J. W., Boothby, M., Umpleby, A.M., Shojaee-Moradie, F., F Shojaee-Moradie, JW Tomlinson, K McGee, Boothby, M, M Shahmanesh, Umpleby, A. M., Gathercole, LL, McGee, K, Das, S., Shahmanesh, Mohsen, Tomlinson, JW, Shahmanesh, M, AM Umpleby, Das, S   +26 more
core   +1 more source

Effect of a high intake of conjugated linoleic acid on lipoprotein levels in healthy human subjects [PDF]

, 2010
Background -Trans fatty acids are produced either by industrial hydrogenation or by biohydrogenation in the rumens of cows and sheep. Industrial trans fatty acids lower high-density lipoprotein (HDL) cholesterol, raise low-density lipoprotein (LDL ...
Wanders Anne J., Siebelink, E., Brouwer, I.A.; id_orcid, Martijn B. Katan, Katan Martijn B., Martijn B Katan, Ingeborg A Brouwer, Brouwer, I.A., Els Siebelink, Anne J. W, Katan, M.B.; id_orcid, Katan, M.B., Anne J Wanders, Siebelink Els, Wanders, A.J., Ingeborg A. Brouwer, Brouwer Ingeborg A.   +16 more
core   +1 more source

Uptake of synthetic low density lipoprotein by leukemic stem cells — a potential stem cell targeted drug delivery strategy [PDF]

, 2010
Chronic Myeloid Leukemia (CML) stem/progenitor cells, which over-express Bcr-Abl, respond to imatinib by a reversible block in proliferation without significant apoptosis.
Jørgensen, Heather G., Jorgensen, Heather G., Tessa L. Holyoake, Heather G. Jørgensen, Scobie, Linda; id_orcid, Elliott, Moira A., Scobie, Linda, Crossan, Claire, Hatziieremia, Sophia, Zhou, Peixun; id_orcid, Elliott, Moira A, Sophia Hatziieremia, Michie, Alison M, Holyoake, Tessa L., Holyoake, Tessa L, Jørgensen, Heather G, Alison M. Michie, Halbert, Gavin W., Linda Scobie, Gavin W. Halbert, Moira A. Elliott, Claire Crossan, Michie, Alison M., Peixun Zhou, Halbert, Gavin W, Zhou, Peixun   +25 more
core   +1 more source

The physiopathology of lipoprotein a

Frontiers in Bioscience, 2010
Lipoprotein(a) (also called Lp(a)) is a lipoprotein subclass. Different studies have identified Lp(a) as a putative risk factor for atherosclerotic diseases such as coronary artery disease and stroke. The physiological role of Lp(a) in humans is still unclear, but it seems that individuals with low concentrations of plasma Lp(a) manifest no deficiency ...
GALVANO, Fabio, MALAGUARNERA M, VACANTE M, MOTTA, Massimo, RUSSO C, MALAGUARNERA M, D'ORAZIO N, MALAGUARNERA, Lucia   +7 more
openaire   +3 more sources

Contemporary patterns of lipoprotein(a) testing and associated clinical care and outcomes

American Journal of Preventive Cardiology, 2023
Objective: Elevated lipoprotein(a) [Lp(a)] is associated with atherosclerotic cardiovascular disease, yet little is known about Lp(a) testing patterns in real-world practice.
Michelle D. Kelsey, Hillary Mulder, Karen Chiswell, Zachary M. Lampron, Ester Nilles, Jacquelyn P. Kulinski, Parag H. Joshi, W. Schuyler Jones, Alanna M. Chamberlain, Thorsten M. Leucker, Wenke Hwang, M. Wesley Milks, Anuradha Paranjape, Jihad S. Obeid, MacRae F. Linton, Shia T. Kent, Eric D. Peterson, Emily C. O'Brien, Neha J. Pagidipati   +18 more
doaj   +1 more source

Assessing the Accuracy of Estimated Lipoprotein(a) Cholesterol and Lipoprotein(a)‐Free Low‐Density Lipoprotein Cholesterol

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2022
Background Accurate measurement of the cholesterol within lipoprotein(a) (Lp[a]‐C) and its contribution to low‐density lipoprotein cholesterol (LDL‐C) has important implications for risk assessment, diagnosis, and treatment of atherosclerotic ...
Weili Zheng, Michael Chilazi, Jihwan Park, Vasanth Sathiyakumar, Leslie J. Donato, Jeffrey W. Meeusen, Mariana Lazo, Eliseo Guallar, Krishnaji R. Kulkarni, Allan S. Jaffe, Raul D. Santos, Peter P. Toth, Steven R. Jones, Seth S. Martin   +13 more
doaj   +1 more source