Results 71 to 80 of about 20,292 (247)

Remnant Cholesterol:Should it be a Target for Prevention of ASCVD?

Purpose of ReviewTo summarize studies analyzing whether remnant cholesterol should be a target for prevention of atherosclerotic cardiovascular disease (ASCVD).Recent FindingsThere is a growing body of evidence from epidemiologic and Mendelian ...
Nordestgaard, Børge Grønne, Langsted, Anne, Doi, Takahito   +2 more
core   +1 more source

10-year ASCVD risk is positively correlated with depressive symptoms in a large general population

, 2019
Background To explore the potential correlation between 10-year atherosclerotic cardiovascular disease (ASCVD) risk and depressive symptoms in a general population. Methods A cross-sectional study involving 11,956 permanent residents of Liaoning Province
Guo-Zhe Sun, Ying-Xian Sun, Ning Ye, Shao-Jun Wu, Ying Zhou   +4 more
core   +1 more source

Angiopoietin‐like protein 3 complete and partial deficiency markedly accelerates apolipoprotein B48 and B100 metabolism in triglyceride‐rich lipoproteins in humans

Journal of Internal Medicine, EarlyView.
Abstract Background Angiopoietin‐like protein 3 (ANGPTL3) is a key circulating regulator of triglyceride metabolism and a promising pharmacological target. The physiological consequences of profound ANGPTL3 deficiency can be explored in individuals with inherited loss‐of‐function (LOF) variants, who show reduced lifetime risk of atherosclerotic ...
Marcello Arca, Elias Björnson, Laura D'Erasmo, Alessia Di Costanzo, Simone Bini, Ilenia Minicocci, Daniele Tramontano, Stella Covino, Giuseppe Ciarlo, Manuela Lombardi, Sanni Söderlund, Niina Matikainen, Linda Andersson, Martin Adiels, Marja‐Riitta Taskinen, Chris J. Packard, Jan Borén   +16 more
wiley   +1 more source

Co‐Design of Strategies to Support the Implementation of a Paediatric Risk‐Reduction Pathway for Familial Hypercholesterolaemia

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Objectives Familial hypercholesterolaemia (FH) affects 1 in 311 people. Left untreated, it elevates LDL‐cholesterol from early life and drives premature atherosclerotic cardiovascular disease. Despite paediatric guidelines for early lipid‐lowering, detection and management in Australia remain suboptimal.
Mitchell Sarkies, Shubha Srinivasan, Ari Horton, Jacquie Garton‐Smith, Gerald F. Watts, Christine Tawtel, Jenny Della‐Vedova, Kristen J. Nowak, Jing Pang, Andrew Martin   +9 more
wiley   +1 more source

Integrative methylation and miRNA dysregulation in dlPFC reveal distinct molecular signatures of suicide and non‐suicide subtypes in major depressive disorder

Psychiatry and Clinical Neurosciences, EarlyView.
Aim Major depressive disorder (MDD) is a leading cause of disability and carries a high risk of suicide. MicroRNAs (miRNAs) are epigenetic regulators implicated in MDD and can be regulated by DNA methylation, potentially reshaping downstream gene networks.
Aleena Francis, Yogesh Dwivedi
wiley   +1 more source

ASCVD Risk Refinement with NT-proBNP for Statin Allocation among Low- and Intermediate-Risk Individuals [PDF]

Background: Statin trials targeting low- to intermediate-risk individuals, namely MEGA, JUPITER, and HOPE-3, have demonstrated benefit of statin use for primary prevention of atherosclerotic cardiovascular disease (ASCVD), but are poorly reflected in ...
Bos, Daniel; id_orcid, Kavousi, Maryam, Ikram, M. Kamran, Leening, Maarten J.G.; id_orcid, Pavlović, Jelena, Ikram, M. Arfan   +5 more
core   +1 more source

Prevalence and clinical characteristics of patients with hsCRP testing and test-confirmed systemic inflammation among individuals with atherosclerotic cardiovascular disease with or without chronic kidney disease in the United States (PLUTUS)

American Journal of Preventive Cardiology
Background: Systemic inflammation (SI) is a risk factor for atherosclerotic cardiovascular disease (ASCVD) and is most commonly assessed by measuring levels of high-sensitivity C-reactive protein (hsCRP).
Lei Lv, Jigar Rajpura, Meixia Liu, Matt Strum, Benjamin Chastek, Jonathan Johnson, Ty J. Gluckman   +6 more
doaj   +1 more source

Healthy Lifestyle Most Important for Prevention of ASCVD

AJN, American Journal of Nursing, 2019
According to this study: A healthy lifestyle throughout life is the most important factor in preventing atherosclerotic cardiovascular disease.Lifestyle and risk factors should be considered when deciding whether pharmacotherapy is needed for primary prevention.
openaire   +3 more sources

Modified Sleep Apnea Severity Index and Cardiovascular Risk in CPAP‐Intolerant OSA Patients

The Laryngoscope, Volume 136, Issue 7, Page 3262-3270, July 2026.
The modified sleep apnea severity index (mSASI) combines patient anatomy, weight, sleep study metrics, and symptoms into a composite OSA index ranging from 1 (least severe) to 3 (most severe). Our study found that mSASI correlated better with baseline cardiovascular risk measured by the 5‐year Framingham Risk Score compared to the AHI.
Praneet C. Kaki, Jennifer A. Goldfarb, Melissa Xu, Daniel J. Campbell, Nicole Molin, Erin Creighton, Thomas M. Kaffenberger, Maurits Boon, Colin Huntley   +8 more
wiley   +1 more source

ROC curve and AUC comparison of the NVAI for ASCVD risk and CVD.

, 2018
(A) ROC curve for the prediction of the ASCVD risk using internal data set. (B) External validation for the prediction of the ASCVD risk using a subgroup of KNHANES IV-V.
Yu-Jin Kwon (5746436), A-Ra Cho (5746433), Ji-Won Lee (284708), Sung-Kwan Oh (5746430), Hye-Sun Lee (509388)   +4 more
core   +1 more source