Results 111 to 120 of about 10,703 (258)

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

Hepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog, Reika Fujiwara, Stephanie Q. Pan, Khairat B. El‐Baradie, Hye Yeon Choi, Sonal Sinha, Qihong Yang, Kinji Asahina, Yibu Chen, Meng Li, Matthew Salomon, Stanley W.‐K. Ng, Hidekazu Tsukamoto   +12 more
wiley   +1 more source

Unveiling Endotypes in Systemic Lupus Erythematosus Through Multiomic Analysis: Insights Into Cardiovascular and Renal Complications

Arthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) shows clinical and molecular heterogeneity, and cardiovascular (CV) complications and lupus nephritis (LN) remain leading causes of morbidity and mortality. This study investigated whether omic profiling can reveal molecular endotypes linked to these outcomes.
Tomás Cerdó, Laurel Woodridge, Sagrario Corrales, Juan Rafael Muñoz‐Castañeda, Ana Isabel Torralbo, Anisur Rahman, Filipa Farinha, Rafaela Ortega Castro, Pedro Segui, Ismael Sanchez‐Pareja, Laura Muñoz‐Barrera, Christian Merlo, Desiree Ruiz‐Vilchez, M. Carmen Ábalos‐Aguilera, Pilar Font, Nuria Barbarroja Puerto, PRECISESADS Clinical Consortium, Lorenzo Beretta, Barbara Vigone, Jacques‐Olivier Pers, Alain Saraux, Valérie Devauchelle‐Pensec, Divi Cornec, Sandrine Jousse‐Joulin, Bernard Lauwerys, Julie Ducreux, Anne‐Lise Maudoux, Carlos Vasconcelos, Ana Tavares, Esmeralda Neves, Raquel Faria, Mariana Brandão, Ana Campar, António Marinho, Fátima Farinha, Isabel Almeida, Miguel Angel Gonzalez‐Gay Mantecón, Ricardo Blanco Alonso, Alfonso Corrales Martínez, Ricard Cervera, Ignasi Rodríguez‐Pintó, Gerard Espinosa, Rik Lories, Ellen De Langhe, Nicolas Hunzelmann, Doreen Belz, Torsten Witte, Niklas Baerlecken, Georg Stummvoll, Michael Zauner, Michaela Lehner, Eduardo Collantes, Ma Carmen Castro‐Villegas, Norberto Ortego, María Concepción Fernández Roldán, Enrique Raya, Inmaculada Jiménez Moleón, Enrique de Ramon, Isabel Díaz Quintero, Pier Luigi Meroni, Maria Gerosa, Tommaso Schioppo, Carolina Artusi, Carlo Chizzolini, Aleksandra Zuber, Donatienne Wynar, Laszló Kovács, Attila Balog, Magdolna Deák, Márta Bocskai, Sonja Dulic, Gabriella Kádár, Falk Hiepe, Velia Gerl, Silvia Thiel, Manuel Rodriguez Maresca, Antonio López‐Berrio, Rocío Aguilar‐Quesada, Héctor Navarro‐Linares, Marta Alarcón‐Riquelme, Alejandro Escudero‐Contreras, M. Ángeles Aguirre‐Zamorano, Carlos Perez‐Sanchez, Elizabeth C. Jury, Chary Lopez‐Pedrera   +84 more
wiley   +1 more source

Rimplasty: An Arthroscopic Technique for Patients With Isolated Patellar Chondromalacia Based on Autologous Matrix‐induced Chondrogenesis+ and Limited Trochleoplasty

Arthroscopy Techniques, EarlyView.
Abstract Anterior knee pain is a common problem that can be difficult to treat. One potential cause of these symptoms is supratrochlear rim, which has been linked to isolated patellar chondromalacia in patients with patella alta and without any history of patellar dislocation or subluxation.
Tomasz Piontek, Bartosz Bąbik, Jakub Bąbik, Artur Banach   +3 more
wiley   +1 more source

Arthroscopic Treatment of Schatzker Type III Tibial Plateau Fractures Using a Combination of Bioabsorbable Interference Screws and Cannulated Screws

Arthroscopy Techniques, EarlyView.
Abstract Schatzker type III tibial plateau fractures, characterized by a pure depression of the lateral articular surface, predominantly affect osteoporotic, middle‐aged, and elderly patients. Successful management requires anatomical reduction and stable fixation to minimize complications like post‐traumatic arthritis.
Renbang Huang, Zeming Li, Xifan Zheng, Jun Yao   +3 more
wiley   +1 more source

Combined Posteromedial Loop Stitch and All‐Inside Anterior Suture Technique for Medial Meniscus Ramp Lesion Repair

Arthroscopy Techniques, EarlyView.
Abstract Medial meniscus ramp lesions have historically been underdiagnosed and often overlooked during arthroscopic procedures. Increasing recognition of their prevalence and biomechanical importance, especially with anterior cruciate ligament injuries, has recently made these lesions a key focus in knee surgery and research.
Catarina Reis Rodrigues, Tiago Puga, Carolina Oliveira, Francisco Guerra Pinto, Bruno Alpoim, Rómulo Silva   +5 more
wiley   +1 more source

A Single‐Bundle Anterior Cruciate Ligament Reconstruction Technique Using Quadrupled Semitendinosus Tendon With Tibial Double Knotless Anchor Fixation And Femoral Suspensory Fixation

Arthroscopy Techniques, EarlyView.
Abstract Anterior cruciate ligament (ACL) injury is a common sports injury and has a significant effect on knee function. Its injury can seriously affect athletic ability and quality of life and may lead to complications such as secondary osteoarthritis.
Zhenlong Liu, Defu Liu, Jianli Gao, Tianying Tang, Xintong Jiang, Xi Gong   +5 more
wiley   +1 more source

The Biologically Enhanced Anterior Cruciate Ligament Reconstruction With Combined Injection of Harvested Platelet‐Rich Plasma, Thrombin, and Bone Marrow Aspirate Concentrate

Arthroscopy Techniques, EarlyView.
Abstract Despite continuous advances, anterior cruciate ligament reconstruction still struggles to restore full native knee function, as most techniques improve mechanical stability but overlook biological healing. The described superenhanced anterior cruciate ligament reconstruction technique aims to address this biological problem through a quadruple
Akram Aldawoudy, Micheal T. Hirschmann, Ahmed Abdalla Ahmed Abdelgawad, Hesham Mohamed Gawish   +3 more
wiley   +1 more source

Modified Transtibial Pullout Repair for Medial Meniscus Posterior Root Tear Using a Barbed Suture: A Technical Note

Arthroscopy Techniques, EarlyView.
Abstract This technical note describes a modified transtibial pullout repair for medial meniscus posterior root tear incorporating a barbed suture to improve fixation strength and load distribution. The technique combines 2 simple sutures placed near the torn root with a circumferential barbed suture passed through the posteromedial meniscocapsular ...
Nam Jun Baek, Wonchul Choi, Jae‐Young Park, Jae Youn Yoon, Jonghyun Park, Jun‐Bae Kim   +5 more
wiley   +1 more source

Total Elbow Arthroplasty: Tips and Tricks in the Setting of Arthritis and Fracture Care

Arthroscopy Techniques, EarlyView.
Abstract The aim of this article is to illustrate our technique for total elbow arthroplasty, acknowledging the key technological advancements and evidence‐based techniques that have emerged in the last 2 decades. In this technical note, we describe our pearls for a reproducible and reliable total elbow arthroplasty procedure.
Benjamin Kerzner, Kyleen Jan, Alexander L. Hornung, John F. Hoy, Xavier C. Simcock   +4 more
wiley   +1 more source

Posterior Cruciate Ligament Reconstruction: A Technique Utilizing Tibial Double Knotless Anchors Fixation and Femoral Suspensory Fixation

Arthroscopy Techniques, EarlyView.
Abstract The posterior cruciate ligament (PCL) is a critical stabilizing structure within the knee joint. Although its injury is relatively uncommon, severe cases can lead to significant dysfunction and long‐term sequelae. PCL reconstruction is an essential treatment for PCL injuries, and among traditional techniques, trans‐tibial interference screw ...
Zhenlong Liu, Defu Liu, Tianying Tang, Tong Pan, Xintong Jiang, Xi Gong   +5 more
wiley   +1 more source