Results 121 to 130 of about 20,771 (305)

MEDICAL AND SURGICAL ASEPSIS

open access: yesAJN, American Journal of Nursing, 1935
Mode of access: Internet.
openaire   +2 more sources

Knowledge Levels of Nurses and Physicians About Asepsis Techniques and Definitions

open access: yesEurasian Journal of Medicine, 2019
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Ayşen Baş, Sevgi Özbek
doaj  

Rational Design of Broad‐Spectrum Anti‐Enteroviral Molecular Glues Targeting Enteroviral RNAi Suppressors

open access: yesAdvanced Science, EarlyView.
By leveraging this homodimerization mechanism, molecular glues were rationally designed to induce dysfunctional 3A dimerization, thereby restoring antiviral RNAi. The optimal molecular glue, VTP‐32, demonstrated potent and pan‐enterovirus (groups A, B, D) antiviral effects.
Yuan Fang   +13 more
wiley   +1 more source

Effect of skill-based educational training for ambulance personnel on neonatal transport for newborn care in coastal South India – a single arm intervention study [version 2; peer review: 1 approved, 2 approved with reservations]

open access: yesF1000Research
Background Quality of neonatal transport services may impact outcomes. We assessed the effect of skill-based education of ambulance personnel (AP) on outcomes of transported neonates.
Shantharam Baliga B   +7 more
doaj   +1 more source

Avaliação fisiológica e sanitária de diferentes lotes de sementes de paricá (Schizolobium parahyba var. amazonicum (Huber ex Ducke) Barneby) utilizada em SAFs. [PDF]

open access: yes, 2011
Entre as espécies que assumem grande interesse para composição de sistemas agroflorestais está o paricá pertencente à família Caesalpiniaceae. O presente trabalho objetivou avaliar as condições fisiológica e sanitária de sementes de paricá, e assim ...
BARBOSA, L. V. A.   +5 more
core  

Targeting Endogenous Lipophagy: A Novel Strategy to Enhance MSC Osteogenesis and Mineralization for Senile Osteoporosis Therapy

open access: yesAdvanced Science, EarlyView.
Schematic representation of the role of lipophagy in bone mesenchymal stem cells(MSCs). In healthy MSCs, functional lipophagy efficiently degrades lipid droplets to support oxidative phosphorylation and cellular energy production, thereby facilitating osteogenic differentiation and matrix mineralization.
Chaoqiang Chen   +8 more
wiley   +1 more source

Biomimetic Bone Marrow Monocyte Membrane‐Fused Extracellular Vesicles for Targeted Therapy of Myocardial Infarction

open access: yesAdvanced Science, EarlyView.
This study develops a biomimetic delivery system (M‐hEV) by fusing monocyte membranes with extracellular vesicles for targeted therapy of damaged cardiac tissue. The system homes to injured myocardium through specific molecular pathways. In a myocardial infarction model, M‐hEV effectively accumulates in the heart, reduces infarct size, alleviates ...
Jiaxin Song   +10 more
wiley   +1 more source

Potilaan infuusiolääkityksen turvallisuus lääkkeenannon oikeellisuuden ja aseptiikan näkökulmasta [PDF]

open access: yes, 1972
Opinnäytetyön tarkoituksena oli kartoittaa strukturoidulla havainnoinnilla, miten aseptiikka ja lääkkeenannon oikeellisuus toteutuvat käytännön hoitotyössä laskimonsisäistä antibioottihoitoa saavien potilaiden hoidossa Helsingin ja Uudenmaan ...
Saarinen, Atte, Säynäjärvi, Iiro
core  

Drug‐Induced Cuproptosis Defines the Therapeutic Window of Celecoxib in Intervertebral Disc Degeneration via the HSP90‐RBX1 Axis

open access: yesAdvanced Science, EarlyView.
This study reveals the dual role of celecoxib in intervertebral disc degeneration. While low concentrations are protective, high concentrations induce toxicity by upregulating HSP90, which synergizes with USP15 to deubiquitinate and stabilize RBX1. This leads to degradation of COMMD1/ATP7B, copper dyshomeostasis, and ultimately, cuproptosis.
Youfeng Guo   +11 more
wiley   +1 more source

Decoding Undesirable Inflammatory Responses of Nucleic Acid‐Delivering Lipid Nanoparticles

open access: yesAdvanced Science, EarlyView.
Lipid nanoparticles (LNPs) enable efficient nucleic acid delivery, but their immunogenicity is a double‐edged sword. This review explores LNP‐driven innate and adaptive immunity, covering lipid components, endosomal escape, and nucleic acid sensing.
Ruimin Hu   +6 more
wiley   +1 more source

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