Results 31 to 40 of about 20,771 (305)

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Outbreak of Achromobacter xylosoxidans and Ochrobactrum anthropi Infections after Prostate Biopsies, France, 2014

Emerging Infectious Diseases, 2016
We report an outbreak of healthcare-associated prostatitis involving rare environmental pathogens in immunocompetent patients undergoing transrectal prostate biopsies at Hôpital Édouard Herriot (Lyon, France) during August 13–October 10, 2014.
Skerdi Haviari, Pierre Cassier, Cédric Dananché, Monique Hulin, Olivier Dauwalder, Olivier Rouvière, Xavier Bertrand, Michel Perraud, Thomas Bénet, Philippe Vanhems   +9 more
doaj   +1 more source

Development and Validation of the Infection Prevention Appraisal Scale

Nursing Reports, 2023
It has been emphasized that future studies aimed at improving adherence to infection prevention guidelines should focus on beliefs in, e.g., self-efficacy.
Maria Lindberg, Magnus Lindberg
doaj   +1 more source

Ten Years of Experience Training Non-Physician Anesthesia Providers in Haiti. [PDF]

, 2009
Surgery is increasingly recognized as an effective means of treating a proportion of the global burden of disease, especially in resource-limited countries. Often non-physicians, such as nurses, provide the majority of anesthesia; however, their training
AF Ouro-Bang’na Maman, AF Smith, BL Grundy, D Hansen, D Ozgediz, DC Simonson, F Mullan, F Mullan, I Walker, IA Walker, JP Abenstein, K Chu, KA Torgersen, Kathryn Chu, LC Ivers, M Philips, M Zimmerman, Miguel Trelles, MN Cherian, MS McAuliffe, Nathan Ford, Organization PAH, P Adnet, P Chatterjee, PE Farmer, Peter Rosseel, S Jochberger, SC Hodges, Seydouba Guilavogui, T Lokossou, TG Weiser, WA Tweed   +31 more
core   +2 more sources

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Prevention of prosthetic joint infection in total hip and knee arthroplasties: Evidence based recommendations

Nigerian Journal of Medicine, 2019
Prosthetic joint infection is a dreaded complication of Total Joint Arthroplasty. Prevention, which is far more cost effective, should be of paramount importance to the arthroplasty surgeon.
O J Alonge, C O Ayekoloye, S O Ogunlade, I I Adeoye-Sunday, M O Okunola, T O Alonge   +5 more
doaj   +1 more source

Efficacy of prophylactic platelet rich plasma (PRP) following open saphenous vein harvesting in cardiac surgery

Frontiers in Bioscience-Elite, 2022
Background: Wound infection represents a frequent trouble following open saphenous vein harvesting in cardiac surgery. Platelets’ growth factors are crucial for the healing process.
Federica Jiritano, Raffaele Serra, Antonio Nenna, Antonio Curcillo, Francesco Villella, Francesco Nappi, Camilla Chello, Massimo Chello, Pasquale Mastroroberto, Giuseppe Filiberto Serraino   +9 more
doaj   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Work conditions and occupational health of dentists in Brazilian Public Health System

Medicina y Seguridad del Trabajo, 2014
Introduction: work healthy conditions are essential for a great professional performance. Objective: To verify the perception of dentists regarding structural and healthy conditions of dental offices in the Brazilian Public Health System (SUS) and their ...
Suzely Adas Saliba Moimaz, Tânia Adas Saliba Rovida, Milene Moreira Silva, Mirelli Ramiro da Silva, Cléa Adas Saliba Garbin   +4 more
doaj   +1 more source

Pathogenicity of aseptic Bursaphelenchus xylophilus. [PDF]

PLoS ONE, 2012
Pine wilt is a disease of pine (Pinus spp.) caused by the pine wood nematode (PWN), Bursaphelenchus xylophilus. However, the pathogenic mechanism of pine wilt disease (PWD) remains unclear.
Li-hua Zhu, Jianren Ye, Sapna Negi, Xu-ling Xu, Zhang-li Wang, Jin-yi Ji   +5 more
doaj   +1 more source