Results 61 to 70 of about 13,393 (272)

Targeting WDR12 Unleashes T‐Cell‐Mediated Antitumor Activity in Melanoma by Destabilizing CD276

open access: yesAdvanced Science, EarlyView.
WDR12 cooperates with the chaperonin subunit CCT7 to maintain CD276 stability on tumor cells, suppressing T‐cell activity and promoting immune escape. SU14813, a small‐molecule WDR12 inhibitor, reduces CD276 stability and relieves CD276‐mediated T‐cell suppression.
Jie Pan   +10 more
wiley   +1 more source

HOMOIMPLANTE ORTOTÓPICO DE TENDÃO CALCÂNEO EM CÃES: CONSERVAÇÃO, ASSEPSIA E IMPLANTAÇÃO ORTHOTOPIC HOMOLOGOUS COMMON CALCANEOUS TENDON GRAFT IN DOGS: CONSERVATION, ASEPSIS AND IMPLANTATION

open access: yesCiência Rural, 2001
Foi elaborado um modelo experimental de conservação, assepsia e implantação de tendão homólogo ortotópico, para avaliar a resposta orgânica, em 48 cães. Os implantes foram conservados em glicerina a 98%, durante 45 dias a seis meses e, após, reidratados ...
Alceu Gaspar Raiser   +8 more
doaj   +1 more source

Ovarian Cancer Diagnosis and Chemoresistance Prediction Model Based on cfRNA Molecular Signature

open access: yesAdvanced Science, EarlyView.
A deep learning model analyzes cfRNA profiles extracted from the blood of OVCA patients. This innovative approach distinguishes OVCA from healthy controls with high accuracy. Crucially, it reliably predicts patient response to chemotherapy (sensitive versus resistant subgroups).
Qinhao Guo   +14 more
wiley   +1 more source

A novel aseptic technique for micropropagation of Aloe vera mill [PDF]

open access: yesAdvanced Herbal Medicine, 2017
Background and aims:Aloe vera has been used medicinally for several thousands of years in many cultures from Egypt, Greece, and Rome to China, India, and etc. Although Aloe barbadensis propagates vegetative manner in its natural state, but propagation is
Zahra Abbasi
doaj  

Pathogenicity of aseptic Bursaphelenchus xylophilus. [PDF]

open access: yesPLoS ONE, 2012
Pine wilt is a disease of pine (Pinus spp.) caused by the pine wood nematode (PWN), Bursaphelenchus xylophilus. However, the pathogenic mechanism of pine wilt disease (PWD) remains unclear.
Li-hua Zhu   +5 more
doaj   +1 more source

MEDICAL OR TISSUE ASEPSIS. [PDF]

open access: yesJAMA: The Journal of the American Medical Association, 1898
MOTTO:—CLEANSE AND STRENGTHEN. Medical asepsis is but the inward application of the principle contained in the ordinary surgical asepsis, supplemented by the enhancement of the bactericidal properties of the blood serum. The words cleanse and strengthen include all the essentials of tissue or medical asepsis.
openaire   +2 more sources

Material‐Encoded Synchronization of Immunogenic Cell Death With Adenosine A2A Receptor Blockade Reprograms the Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
A bismuth–copper diselenide–based nanoplatform (BSCS@PHY) coordinates immunogenic cell death with local A2A receptor blockade in 4T1 tumors. Thermally triggered shell melting exposes catalytic surfaces for glutathione depletion and chemodynamic ROS generation, while co‐delivering an A2AR antagonist and yeast‐wall adjuvant to enhance dendritic‐cell ...
Xiangting Yi   +12 more
wiley   +1 more source

La scala Asepsis: validazione italiana di uno strumento per la valutazione delle caratteristiche del sito chirurgica

open access: yes, 2015
Introduzione Le infezioni del sito chirurgico rappresentano il 14,6% delle infezioni contratte in ospedale. La sorveglianza attiva ne riduce l’incidenza dal 30% al 50%; a tale scopo esiste la scala ASEPSIS che, tuttavia, non è ancora stata validata in ...
A. Destrebecq   +4 more
core   +2 more sources

Prevention of operative infection in ophthalmic surgery

open access: yesJournal of Clinical Ophthalmology and Research, 2016
Prevention of infection in ocular surgery is based on the science of asepsis and antisepsis not only depends on what we do pre-, intra-, and post-operatively but also depends on how we prepare our patient and personnel.
Uday R Gajiwala   +2 more
doaj   +1 more source

A Hydrogen Sulfide–Releasing Dynamic Hydrogel Modulates Coordinated Neurovascular, Immune, and Angiogenic Responses for Scar‐Suppressed Diabetic Wound Repair

open access: yesAdvanced Science, EarlyView.
ROS‐Responsive H2S Hydrogel (HAPPF) Coordinated Regeneration for High‐Quality Diabetic Wound Repair.A self‐regulating dynamic hydrogel is developed to deliver a fluorogenic H2S donor in response to excessive ROS. Released H2S acts as a master regulator to resolve chronic inflammation (M2 polarization), restore VEGF‐driven angiogenesis, and rebalance ...
Xuyang Ning   +7 more
wiley   +1 more source

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