Results 111 to 120 of about 30,482 (257)

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown   +2 more
wiley   +1 more source

The collective application of shorebird tracking data to conservation

open access: yesConservation Biology, EarlyView.
Abstract Addressing urgent conservation issues, such as the drastic declines of North American migratory birds, requires creative, evidence‐based, efficient, and collaborative approaches. The abundance of over 50% of monitored North American shorebird populations has declined by over 50% since 1980. To address these declines, we developed a partnership
Autumn‐Lynn Harrison   +71 more
wiley   +1 more source

More Inspired, Less Anxious: Well‐Being Impacts of a Self‐Directed Art Museum Visit

open access: yesCurator: The Museum Journal, EarlyView.
ABSTRACT Increasingly, art museums are seen as places that can support human flourishing. We describe a quasi‐experimental investigation of the impacts of a self‐directed art museum visit on adults' subjective well‐being. Data were collected from 363 adults at three art museums in Seattle, WA.
Jessica J. Luke   +18 more
wiley   +1 more source

Traditional production and main characteristics of Galichki kashkaval

open access: yesMljekarstvo, 2014
In this study, principles of traditional production and main characteristics of the traditional sheep cheese Galichki kashkaval from Bistra Mountain are presented.
Dushica Santa, Sonja Srbinovska
doaj  

Fluoride‐Free Mouthwashes Available Over‐The‐Counter in the US‐An Overview

open access: yesInternational Journal of Dental Hygiene, EarlyView.
ABSTRACT Purpose Fluoride‐free mouthwashes (FFM) are commonly used by patients for a variety of cosmetic and/or therapeutic reasons. The purpose of this study was to investigate the composition and purposes of FFM available over‐the‐counter in the US.
Astrid C. Valdivia‐Tapia   +3 more
wiley   +1 more source

Haematological and histopathological monitoring of monosodium glutamate–supplemented feeding in rainbow trout (Oncorhynchus mykiss): A possible modelling for a single health approach

open access: yesJournal of Fish Biology, EarlyView.
Abstract The aim of this study was to investigate the potential effects of monosodium glutamate (MSG), a known flavour enhancer added to many ready‐to‐eat foods, as a feed additive in rainbow trout (Oncorhynchus mykiss). Evaluating the effects of MSG on aquatic organisms will fill the knowledge gap in this field by monitoring the haematological indices
Gonca Alak   +16 more
wiley   +1 more source

The Unexpected Discovery of Paleocene? Coals in Outcrops Thought to Be Cambrian, Al Huqf, Oman

open access: yesJournal of Petroleum Geology, EarlyView.
ABSTRACT Two brown organic deposits were encountered whilst investigating kaolinitic claystones thought to occur at the base of a Cambrian formation at outcrop. The age of these organic deposits is probably Paleocene from palynology. Organic petrography shows that they are subbituminous coals with some oil source potential.
Mohammed H. Al Kindi   +4 more
wiley   +1 more source

Effect of Two Therapeutic Renal Diets on Hormonal and Regulatory Pathways Affecting Calcium Homeostasis in Cats With Early‐Stage Chronic Kidney Disease

open access: yesJournal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT Chronic kidney disease (CKD) is a known risk factor for hypercalcemia in cats. Phosphate‐restricted diets have also been implicated in causing hypercalcemia, in part because phosphate restriction increases the Ca:P ratio. The primary objective of this study was to evaluate the impact of two different therapeutic renal foods on ionized (iCa ...
Jean A. Hall   +4 more
wiley   +1 more source

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