Results 171 to 180 of about 31,085 (321)

PharmVar GeneFocus: CYP1A2—Clinical Impact, Genetic Variation, and Updated Nomenclature

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The Pharmacogene Variation Consortium (PharmVar) provides nomenclature for the highly polymorphic human CYP1A2 gene. CYP1A2 plays a crucial role in the biotransformation of several commonly used drugs, including antipsychotics, antidepressants, anxiolytics, and methylxanthines.
Katalin Monostory   +13 more
wiley   +1 more source

Local realities, global discourses and decolonising the curriculum in a post‐92 UK context: Academic voices on enacting decolonial curriculum change

open access: yesThe Curriculum Journal, EarlyView.
Abstract This study explored how lecturers in a post‐92 UK university conceptualise and enact decolonial curriculum principles within their teaching and programme design. Drawing on semi‐structured interviews with academic staff across multiple disciplines, the research adopts a qualitative, phenomenologically informed approach to examine the interplay
Reece Sohdi
wiley   +1 more source

Assessment of Abuse Potential‐Related Effects of Oral Dried Kratom Leaf Powder in Healthy Normal Participants Following Single and Multiple Daily Doses

open access: yesDrug Testing and Analysis, EarlyView.
In a randomized, double‐blind, placebo‐controlled study of oral dried kratom leaf powder in healthy kratom‐naive adults, no participants met the clinically meaningful opioid withdrawal threshold; abuse‐related treatment‐emergent adverse events occurred more frequently at higher doses but were generally mild and resolved without sequelae; and no serious
Marion Coe   +5 more
wiley   +1 more source

The role of Rho GTPases in facial morphogenesis

open access: yesDevelopmental Dynamics, EarlyView.
The role of small GTPases, RHOA, RAC1, and CDC42 and pathway mediators is reviewed in the context of embryonic facial development. Lip fusion requires cytoskeletal remodeling during morphogenesis of the facial processes and during lip fusion. Fnm, frontonasal mass; lnp, lateral nasal process; mnp, medial nasal process; mxp, maxillary process; np, nasal
Isra Ibrahim, Joy M. Richman
wiley   +1 more source

Social Comparison and Its Association With Disordered Eating Symptoms: A Systematic Review and Meta‐Analysis

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Social comparison has been widely implicated in the etiology and maintenance of body dissatisfaction and eating disorders. At the same time, however, the magnitude of this relationship remains unclear, with existing studies varying widely in methodology, measurement, and sample characteristics.
Fidan Turk   +5 more
wiley   +1 more source

Camera traps reveal use of caves by Asiatic black bears (Ursus thibetanus gedrosianus) (Mammalia: Ursidae) in southeastern Iran

open access: green, 2011
Hadi Fahimi   +5 more
openalex   +2 more sources

Safe and Sound: Is Safeness a Specific Affective Dimension Related to Eating Disorder Behaviors?

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Safeness is a warm, soothing emotional state that is often experienced in the presence of close others. Safeness is thought to be distinct from other positive emotions or the absence of negative emotions and is shown to predict mental health variables over and above other emotions.
Ege Bicaker   +3 more
wiley   +1 more source

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