Results 51 to 60 of about 3,491 (198)

Pedicled and skeletonized single and bilateral internal thoracic artery grafts and the incidence of sternal wound complications: Insights from the Arterial Revascularization Trial [PDF]

open access: yes, 2016
Objectives: The question of whether skeletonized internal thoracic artery harvesting reduces the incidence of sternal wound complications in comparison with the pedicled technique, in the context of single or bilateral internal thoracic arteries, remains
Alastair Gray   +29 more
core   +2 more sources

Association between annual twin delivery volume and severe postpartum hemorrhage in twin pregnancies

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To assess the association between the risk of severe postpartum hemorrhage (PPH) and the annual twin delivery volume of maternity units. Methods JUmeaux MODe d'Accouchement (JUMODA) was a national observational prospective population‐based cohort of twin deliveries in 176 French maternity units performing more than 1500 annual ...
Victoire Pauphilet   +6 more
wiley   +1 more source

Acid sphingomyelinase deficiency: The clinical spectrum of 2 patients who carry the Q294K mutation and diagnostic challenges

open access: yesMolecular Genetics and Metabolism Reports, 2022
Acid sphingomyelinase deficiency (ASMD) is caused by pathogenic variants in the SMPD1 gene. This chronic, progressive, and potentially fatal condition requires prompt specialist care. The diagnosis of ASMD can be delayed or missed if patients that harbor
Ulrike Blümlein   +2 more
doaj   +1 more source

Do Single‐Sex STEM Programs Have Merit? If So, for Whom, on What Measures?

open access: yesScience Education, EarlyView.
ABSTRACT Single‐sex STEM programs—defined here as voluntary, gender‐segregated extracurricular or supplemental activities (e.g., summer camps, workshops, robotics clubs, internships, or citizen science initiatives)—have experienced heightened popularity and scrutiny amid efforts to increase diversity in STEM fields.
Chen Chen   +4 more
wiley   +1 more source

An Australian standard of care for Niemann–Pick disease type C

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background Niemann–Pick disease type C (NP‐C) is the fifth most prevalent lysosomal disorder in Australia. Diagnostic delay is common, impacted by disease heterogeneity, limited awareness within clinical gateway services and exclusion from state‐based newborn screening programmes.
Michel Tchan   +23 more
wiley   +1 more source

Real-life impacts of olipudase alfa: The experience of patients and families taking an enzyme replacement therapy for acid sphingomyelinase deficiency

open access: yesOrphanet Journal of Rare Diseases
Background Acid Sphingomyelinase Deficiency (ASMD) is an ultra-rare autosomal recessive lysosomal storage disorder characterized by intracellular lipid accumulation resulting from reduced function of acid sphingomyelinase.
Eva M. Raebel   +6 more
doaj   +1 more source

Unveiling the Nature of Submillimeter Galaxy SXDF850.6 [PDF]

open access: yes, 2010
We present an 880 micron Submillimeter Array (SMA) detection of the submillimeter galaxy SXDF850.6. SXDF850.6 is a bright source (S(850 micron) = 8 mJy) detected in the SCUBA Half Degree Extragalactic Survey (SHADES), and has multiple possible radio ...
A. B. Peck   +69 more
core   +2 more sources

Reduced risk of dementia with recombinant zoster vaccine in US adults age 65 or older

open access: yesAlzheimer's &Dementia, Volume 22, Issue 5, May 2026.
Abstract INTRODUCTION Herpes zoster vaccines may lower the risk of dementia onset. We evaluated new‐onset dementia among US Medicare beneficiaries ≥65 years old following recombinant zoster vaccination (RZV). METHODS We matched one RZV‐exposed to two RZV‐unvaccinated on age, sex, and race/ethnicity. Individuals were ≥65 years old on the RZV dose 2 date
Susan dos Reis   +8 more
wiley   +1 more source

Enzyme replacement therapy for children with acid sphingomyelinase deficiency in the real world: A single center experience in Taiwan

open access: yesMolecular Genetics and Metabolism Reports, 2023
Background: Acid sphingomyelinase deficiency (ASMD) is a lysosomal storage disease with multi-systemic involvement, with no disease-modifying treatment available. Olipudase alfa is an investigational enzyme product developed to replace the deficient acid
Yu-Wen Pan   +6 more
doaj   +1 more source

Outcomes and salvage strategies for large B‐cell lymphoma progressing after second‐line CAR T‐cell therapy: A DESCAR‐T study from the LYSA group

open access: yesHemaSphere, Volume 10, Issue 5, May 2026.
Abstract Relapse after chimeric antigen receptor (CAR) T‐cell therapy in large B‐cell lymphoma (LBCL) is associated with a dismal prognosis. Although Phase 3 trials have established CAR T‐cells as standard second‐line (2L) therapy, outcomes and optimal management after relapse in this setting remain unknown because no real‐world data are currently ...
Pierre Sesques   +37 more
wiley   +1 more source

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