Results 61 to 70 of about 1,516 (160)

Antidepressants and the risk of hyponatremia: A multi‐institutional cohort study using observational medical outcomes partnership—Common Data Model

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1706-1715, June 2026.
Aim Hyponatremia is a common yet potentially serious adverse event associated with antidepressants. Identifying the antidepressant class with the least risk of hyponatremia would improve patient safety. Methods Using electronic medical records from 15 hospitals standardized into Observational Medical Outcomes Partnership Common Data Model (2003–2023 ...
Kyungyeon Jung, Ju Hwan Kim, Da Eun Hyeon, Jeongmoon Ji, Min Young Lee, Hayun Choi, Dong Yun Lee, Min Woo Kim, Yoonmin Jang, Seonghoon Hwang, Jaehyeong Cho, Seok Young Song, Sang Youl Rhee, Jae Myung Cha, Won‐Woo Seo, Chang‐Won Jeong, Seung‐Jin Kwag, Woo Jin Kim, Jaeuk Hwang, Min‐ho Kim, Rae Woong Park, Ju‐Young Shin   +21 more
wiley   +1 more source

Case Report of Gastrointestinal Bleeding in an Adult with Chronic Visceral Acid Sphingomyelinase Deficiency

Case Reports in Gastrointestinal Medicine, 2019
Introduction. Acid sphingomyelinase deficiency (ASMD, also known as Niemann-Pick Type A and Type B disease) is a rare, inherited metabolic disorder.
David Cassiman, Louis Libbrecht, Wouter Meersseman, Alexander Wilmer   +3 more
doaj   +1 more source

ASMD-FSMD Technique for Designing Digital Devices on FPGA

, 2020
Recently, there has been, on the one hand, an increase in the complexity of digital device designs and, on the other hand, an increase in the requirements for the development time and the reliability of the designs. One of the directions of solving this problem is developing new techniques for designing digital devices.This paper proposes a new ...
openaire   +2 more sources

Acid sphingomyelinase deficiency in France: a retrospective survival study

Orphanet Journal of Rare Diseases
Background Acid sphingomyelinase deficiency (ASMD) or Niemann–Pick disease types A, A/B, and B is a progressive, life-limiting, autosomal recessive disorder caused by sphingomyelin phosphodiesterase 1 (SMPD1) gene mutations.
Wladimir Mauhin, Nathalie Guffon, Marie T. Vanier, Roseline Froissart, Aline Cano, Claire Douillard, Christian Lavigne, Bénédicte Héron, Nadia Belmatoug, Yurdagül Uzunhan, Didier Lacombe, Thierry Levade, Aymeric Duvivier, Ruth Pulikottil-Jacob, Fernando Laredo, Samia Pichard, Olivier Lidove, ASSUR Study Group   +17 more
doaj   +1 more source

Potential Mechanisms of Platelet Dysfunction and Bleeding in Acid Sphingomyelinase Deficiency

Cells
Acid sphingomyelinase deficiency (ASMD) is an autosomal recessive lysosomal storage disorder caused by mutations in the SMPD1 gene, resulting in sphingomyelin accumulation.
Maksim Sysoev, Dmitri Solovyov, Aleksandr Shestopalov, Sergey Kutsev   +3 more
doaj   +1 more source

Allele frequency of pathogenic variants causing acid sphingomyelinase deficiency and Gaucher disease in the general Japanese population

Human Genome Variation
Acid sphingomyelinase deficiency (ASMD) and Gaucher disease (GD) are lysosomal storage disorders associated with hepatosplenomegaly and thrombocytopenia.
Shuhei Sako, Kimihiko Oishi, Hiroyuki Ida, Eri Imagawa   +3 more
doaj   +1 more source

Persistent Arrhythmogenic Effects of COVID‐19: A Comprehensive Analysis of Device Implantation and Antiarrhythmic Interventions in Japan

Journal of Arrhythmia, Volume 42, Issue 3, June 2026.
COVID‐19 was associated with a sustained increase in device implantation and arrhythmia‐related interventions over 2 years. In a nationwide propensity score‐matched cohort, risks of pacemaker, ICD, CRT implantation, ablation procedures, and antiarrhythmic medication initiation remained higher after COVID‐19, supporting long‐term cardiovascular ...
Daisuke Miyamori, Shuhei Yoshida, Masanori Ito   +2 more
wiley   +1 more source

A challenging case of ASMD (acid sphingomyelinase deficiency): A severe interstitial lung disorder in an asplenic patient

Molecular Genetics and Metabolism Reports
Acid sphingomyelinase deficiency (ASMD) is a rare lysosomal storage disorder with multisystemic involvement. We report a 68-year-old asplenic man with late-onset ASMD and severe interstitial lung disease, chronic respiratory failure, and markedly reduced
Arlindo Guimas, Esmeralda Martins
doaj   +1 more source

A retrospective study of morbidity and mortality of chronic acid sphingomyelinase deficiency in Germany

Orphanet Journal of Rare Diseases
Background Acid sphingomyelinase deficiency (ASMD) is a rare, progressive, potentially fatal lysosomal storage disease that exhibits a broad spectrum of clinical phenotypes.
Eugen Mengel, Nicole Muschol, Natalie Weinhold, Athanasia Ziagaki, Julia Neugebauer, Benno Antoni, Laura Langer, Maja Gasparic, Sophie Guillonneau, Marie Fournier, Fernando Laredo, Ruth Pulikottil-Jacob   +11 more
doaj   +1 more source

Acid sphingomyelinase deficiency and Gaucher disease in adults: Similarities and differences in two macrophage storage disorders

JIMD Reports
The lysosomal storage diseases chronic visceral acid sphingomyelinase deficiency (ASMD) and Gaucher disease type 1 (GD1) are both macrophage storage disorders with overlapping clinical manifestations.
Eline C. B. Eskes, Laura vanDussen, Johannes M. F. G. Aerts, Martijn J. C. van derLienden, Mario Maas, Erik M. Akkerman, André B. P. vanKuilenburg, Barbara Sjouke, Carla E. M. Hollak   +8 more
doaj   +1 more source