Results 101 to 110 of about 174,886 (213)

Simplifying Iliotibial Band Lateral Extra‐articular Tenodesis Fixation During Anterior Cruciate Ligament Reconstruction: A Hardware‐Sparing Approach

Arthroscopy Techniques, EarlyView.
Abstract The addition of a lateral extra‐articular tenodesis to anterior cruciate ligament reconstruction has been shown to reduce graft failure and improve rotational stability, but current fixation methods often require additional tunnels or hardware, with risks of tunnel convergence, irritation, and hardware removal. This technical paper describes a
Emmanouil Papakostas, Enejd Veizi, Ashraf Hantouly, Aizel Sherief Palasseril, Merve Bozer Kavukcu, Alan Getgood   +5 more
wiley   +1 more source

Structure, personnel, and initiatives of antimicrobial stewardship programs in pediatric hospitals in the United States based on on-call participation: a cross-sectional survey. [PDF]

Antimicrob Steward Healthc Epidemiol
Alvira-Arill GR, Brace S, Morrisette T, Thacker S, Hamby A, Burgoon R, Gruss Z, Mills A, Lueking R, Mediwala Hornback K.   +9 more
europepmc   +1 more source

Targeting Amastigote and Trypomastigote Phases: Multi‐Epitope Vaccine Strategy Against Trypanosoma cruzi

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Effective vaccines against Trypanosoma cruzi, the causative agent of Chagas disease, are urgently needed. Here, we report the design and in silico validation of a novel multiepitope vaccine construct targeting the key surface proteins ASP‐2 and gp82. Using a comprehensive immunoinformatics pipeline, we identified and selected 38 potent T‐cell (
Maria Karolaynne da Silva, Caio Patrício de Souza Sena, Davi Serradella Vieira, Magdi E. A. Zaki, Leow Chiuan Yee, Shahina Akter, Umberto Laino Fulco, Jonas Ivan Nobre Oliveira, João Firmino Rodrigues‐Neto   +8 more
wiley   +1 more source

Dietary inclusion of Asparagopsis taxiformis significantly reduces methane emissions in dairy cows by mechanistically altering vitamin B12-dependent and other methanogenesis precursor pathways. [PDF]

Microbiome
Lawther K, Dimonaco NJ, Donnelly P, Guinguina A, Krizsan SJ, Huws SA.   +5 more
europepmc   +1 more source

Current evidence and insights on single vs. double dose of basiliximab in adult solid organ transplant recipients: A systematic review

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim The aim of this systematic review was to assess all available clinical data regarding the use of a single dose of basiliximab in solid organ transplantation compared to the standard double dosage, with particular interest in efficacy, safety and cost‐savings.
Alessio Provenzani, Braidon A. Lape, Anneliese M. Harp, Victoria Weisbrod, Lavinia Piazza   +4 more
wiley   +1 more source

How to Handle Hard-to-Purify Polymers: Ammonium Sulfate Precipitation of rPEG as a Prototype for Amorphous and Flexible Polymers. [PDF]

ACS Macro Lett
Simon L, Dreier P, Frey H.
europepmc   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Microcephaly-associated genes asp and Sas4 influence chromatin organization and nuclear lamina structure in Drosophila melanogaster. [PDF]

Development
Mengistu DY, Marzullo M, Pellacani C, Marchetti M, Terribili M, Montivero Morales E, Somma MP, Ciapponi L.   +7 more
europepmc   +1 more source

What Makes an “Ideal” Cell Line for Recombinant Adeno‐Associated Virus Production?

Biotechnology and Bioengineering, EarlyView.
Several host cell types have been used to produce rAAVs to date. Cell line‐specific traits that are beneficial in the context of rAAV manufacturing are reviewed here, with the goal of developing a consensus on the ‘ideal’ characteristics that an rAAV production host should possess (created with Biorender.com).
James Conheady, Nicholas Donohue, Alexandra Bogdanovic, Sharon Davin, Brian Glennon, Niall Barron, C. Mark Smales   +6 more
wiley   +1 more source

Are pulmonary neuroepithelial bodies sensors for acute airway hypoxia implicated in the central regulation of breathing? [PDF]

PLoS One
Brouns I, Schnorbusch K, Pintelon I, Lembrechts R, De Proost I, Kemp PJ, Timmermans JP, Adriaensen D.   +7 more
europepmc   +1 more source