Results 111 to 120 of about 174,886 (213)

Metabolic Flux Analysis Reveals Cell Line‐Specific Rewiring in CHO Cells Following TCA Cycle Intermediate Feeding for Bioprocess pH Control

Biotechnology and Bioengineering, EarlyView.
ABSTRACT Chinese hamster ovary (CHO) cells are the leading host for recombinant therapeutic protein production in the biopharma industry. In this study, we investigated how feeding acidic forms of tricarboxylic acid (TCA) cycle intermediates—malic acid, succinic acid, and α‐ketoglutaric acid—affects cell culture performance and metabolism in two ...
Sarah A. Sacco, Kevin J. Ruiz‐Márquez, Rachel Moen, Irina Trenary, Xiaolin Zhang, Xiaowen Wang, Malik Padellan, Henry Lin, Jamey D. Young   +8 more
wiley   +1 more source

Serological and biochemical characterization of Aspergillus fumigatus Asp f 10 as a potential diagnostic marker in ABPA and related respiratory diseases. [PDF]

Front Allergy
Ghosh S, Dasgupta A, Sarkar RK, Chatterjee C, Padukudru Anand M, Bhattacharya K, Bakshi U, Sircar G.   +7 more
europepmc   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

Structure of ergosteryl-aspartate synthase reveals how an entrapped tRNA is used like a prosthetic swinging arm in the synthesis of aminoacylated sterols. [PDF]

Nat Commun
Murayama H, Yakobov N, Mahmoudi N, Legrosdidier S, Fournier N, Zuttion S, Matsumoto K, Nishimura M, Ji J, Senger B, Huck L, Gamper HB, Kise Y, Kleiner RE, Frechin M, Hou YM, Becker HD, Itoh Y, Fischer F, Nureki O.   +19 more
europepmc   +1 more source

Initiating Market Formation Through Local Policy Innovation: Plot Handover as a Driver for Circular Construction

Business Strategy and the Environment, EarlyView.
ABSTRACT The transition to circular construction suffers from uncertainties related to costs, market realities, supply, regulations and expertise using secondary materials in building projects. Uncertainties are large, and resolving them needs policy interventions.
Erkki‐Jussi Nylén, Tommi Halonen
wiley   +1 more source

Beyond the plate: Exploring students' experiences with a food education intervention in an after-school program setting. [PDF]

Public Health Pract (Oxf)
Beinert C, Nistås A, Myrvoll EA, Nordgård Vik F, Røed M.   +4 more
europepmc   +1 more source

Reclaiming Anatomy as Method: From Morphological Reasoning to Clinical Relevance

Clinical Anatomy, EarlyView.
ABSTRACT In recent decades, molecular biology and omics technologies have profoundly reshaped biomedical research, with genomics, proteomics, and other high‐throughput approaches dominating scientific agendas and funding priorities. Within this molecular paradigm, however, the anatomical sciences face an epistemic and institutional tension: morphology,
Katia Cortese, Marco Frascio
wiley   +1 more source

Temporal trends in antimicrobial consumption and an investigation of hospital antimicrobial stewardship activities through structured interviews. [PDF]

Antimicrob Steward Healthc Epidemiol
Honda H, Murakami S, Kosugi T, Ito A, Hata T, Sasaki Y, Hamamoto Y, Wakugawa T, Shiroma M, Nakamura K, Shiohira H, Karasawa K, Tokuda Y.   +12 more
europepmc   +1 more source

Determining the Nutritional Potential of Ancient Wheat Species: A Closer Look at Starch and Protein Digestibility, and Phenolic Acid Content

Cereal Chemistry, EarlyView.
ABSTRACT Background and Objectives The recent trend towards healthy food choices and sustainable agriculture has revived interest in underutilized wheat species such as emmer, einkorn, and spelt. Given these developments, the objective of the study was to compare the differences in chemical composition and digestibility characteristics among ...
Sathsara Deyalage, Sijo Joseph Thandapilly, James Duncan House, Adam Franczyk, Amanda Gomes Almeida Sá, Maneka Malalgoda   +5 more
wiley   +1 more source

Aspartic acid-facilitated remineralization: a bio-inspired alternative to fluoride for enamel repair. [PDF]

Front Bioeng Biotechnol
Ivanova A, Buzova V, Potapova D.
europepmc   +1 more source