Results 131 to 140 of about 99,734 (259)

GhLYK5-mediated GhNIT4B activates asparagine and ROS accumulation enhancing cotton Verticillium wilt resistance. [PDF]

J Biol Eng
Li N, Guo W, Pan G, Wang X, Sun Z, Guo H, Cheng H, Su X.   +7 more
europepmc   +1 more source

Asparagin [PDF]

, 2017
openaire   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

Andrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos, Marie‐Pier Scott‐Boyer, Arnaud Droit, Robert S. Viger, Jacques J. Tremblay   +4 more
wiley   +1 more source

NMR metabolomics reveals metabolic alterations in a novel mouse model of neurodegeneration. [PDF]

Front Neurosci
Mercer GV, Adams H, Locke DP, Kiefte S, Harvey N, Coffey R, Schneider CM, Cahill LS.   +7 more
europepmc   +1 more source

Asparagine Measurement [PDF]

, 2020
openaire   +1 more source

Proteomic profile of CSF obtained at the time of diagnosis determines amyotrophic lateral sclerosis progression and survival: CXCL7 levels in disease prognosis and survival

Brain Pathology, EarlyView.
Untargeted multiomic profiling of cerebrospinal fluid reveals that proteomic, but not lipidomic, signatures robustly distinguish ALS patients from controls and stratify individuals by survival, highlighting marked molecular differences between short survival and long survival disease.
Sergio Roca‐Pereira, Yaiza López‐Sampere, Pol Mengod‐Soler, Mario Peña‐Fonteboa, Carla Marco, Alejandro Caravaca‐Puchades, Raúl Domínguez, Juan Francisco Vázquez‐Costa, Enrique Santamaría, Joaquín Fernández‐Irigoyen, María J. Colomina, Isabel León Moreno, Antonio Martínez Yélamos, Sergio Martínez Yélamos, Gabriel Santpere, Elia Obis, Manuel Portero‐Otín, Gerard Piñol‐Ripoll, Mónica Povedano, Pol Andrés‐Benito   +19 more
wiley   +1 more source

The potential for biased signalling in the P2Y receptor family of GPCRs

British Journal of Pharmacology, EarlyView.
The purinergic receptor family is primarily activated by nucleotides, and contains members of both the G protein coupled‐receptor (GPCR) superfamily (P1 and P2Y) and ligand‐gated ion channels (P2X). The P2Y receptors are widely expressed in the human body, and given the ubiquitous nature of nucleotides, purinergic signalling is involved with a plethora
Claudia M. Sisk, Simon Pitchford, Graham Ladds   +2 more
wiley   +1 more source

<i>Asparagine synthetase (ASNS)</i> Drives Tumorigenicity in Small Cell Lung Cancer. [PDF]

Biomedicines
Jeong M, Kim BC, Choi HJ, Lee GT, Jang SM, Kim KB.   +5 more
europepmc   +1 more source

Covalent drug discovery: Progress against key targets, emerging strategies and lessons learnt

British Journal of Pharmacology, EarlyView.
Abstract Covalent drug discovery is currently experiencing a boom in industrial and academic interest. To date, at least 75 covalent drugs have received regulatory approval, targeting both traditional target classes and more challenging proteins for which other approaches failed. In many cases, unique aspects of covalent targeting are essential for the
Charles P. Brown, Alan Armstrong, David J. Mann   +2 more
wiley   +1 more source

Nail Amino Acid and Trace Element Profiles and Their Association with Clinical Severity in Nail Psoriasis. [PDF]

Clin Cosmet Investig Dermatol
Özen T, Gürel MS, Erdem O, Özçelik D, Pastacı Özsobacı N, Selek Ş, Köktaşoğlu F.   +6 more
europepmc   +1 more source