Results 251 to 260 of about 202,771 (390)

Optimizing (Bio) Catalysis with Liquid‐Liquid Phase Separation Systems

ChemSystemsChem, EarlyView.
This review highlights how LLPS creates membraneless compartments involved in different scenarios in nature. It further explores different examples that focus on the development of synthetic coacervates that enhance catalytic efficiency by concentrating reactants, or by the direct influence of the coacervates building blocks themselves.
David Q. P. Reis, Joana Calvário, Inês Chibeles, Mohit Kumar, Ana S. Pina   +4 more
wiley   +1 more source

Amino Acid Profile Alterations in the Mother-Fetus System in Gestational Diabetes Mellitus and Macrosomia. [PDF]

Int J Mol Sci
Frankevich NA, Tokareva AO, Yuriev SY, Chagovets VV, Kutsenko AA, Novoselova AV, Karapetian TE, Lagutin VV, Frankevich VE, Sukhikh GT.   +9 more
europepmc   +1 more source

Critical evaluation of three cryo‐EM structures of particulate methane monooxygenase by quantum refinement

Acta Crystallographica Section D, EarlyView.
We have studied the copper sites in three cryogenic electron‐microscopy structures of particulate methane monooxygenase with quantum refinement. We show that the CuA, CuC and CuD sites are correctly modelled and that the CuB site is mononuclear in all structures, whereas we find no support for copper in the suggested trinuclear active site or two sites
Gayathri Yuvaraj, Kristoffer J. M. Lundgren, Elija Veenman, Esko Oksanen, Ulf Ryde   +4 more
wiley   +1 more source

Hyperthermophilic L-Asparaginase from <i>Thermococcus sibiricus</i> and Its Double Mutant with Increased Activity: Insights into Substrate Specificity and Structure. [PDF]

Int J Mol Sci
Dumina MV, Zhdanov DD, Veselovsky AV, Pokrovskaya MV, Aleksandrova SS, Minyaev ME, Varfolomeeva LA, Matyuta IO, Boyko KM, Zhgun AA.   +9 more
europepmc   +1 more source

Carbon pathways and trophic attributes are conserved in carnivorous reef fishes across a major human disturbance gradient

Journal of Animal Ecology, EarlyView.
Our research leverages a natural, ecosystem‐scale experiment and cutting‐edge molecular isotope approaches to reveal that coral reef food web structure and energy flow can remain consistent across a gradient of human disturbance. Abstract Habitat degradation and overexploitation are key drivers of biodiversity loss globally.
Matthew D. Ramirez, Kelton W. McMahon, Neil Rooney, Rana W. El‐Sabaawi, Julia K. Baum   +4 more
wiley   +1 more source

Asparaginase and Autophagy Inhibitors Effectively Remove Senescent Cells by Synergistically Limiting Asparagine Supply. [PDF]

Aging Cell
Huang Z, Liu X, Zhou X, Chen K, Diao H, Wang M, Wei J, Li Z, Yang Y, Mao Z, Yu W.   +10 more
europepmc   +1 more source

QM Metadynamics study on peptide deamidation [PDF]

, 2010
Bulo, Rosa E, Catak, Saron, De Sterck, Bart, Van Speybroeck, Veronique, Waroquier, Michel   +4 more
core   +1 more source

Multilocus sequence typing of the invasive pest Halyomorpha halys (Hemiptera: Pentatomidae) and associated endosymbiont reveals unexplored diversity

Insect Science, EarlyView.
A multilocus sequence typing approach is proposed to explore Halymorpha halys genetic diversity, taking into consideration both insect nuclear markers and markers from the gut symbiont “Candidatus Pantoa carbekii.” Increased information was revealed regarding the number of distinct holobiont haplotypes in native and invasive populations of the pest ...
Matteo Dho, Matteo Montagna, Chenxi Liu, Giulia Magoga, Giobbe Forni, Alberto Alma, Elena Gonella   +6 more
wiley   +1 more source

The role of the asparagine-linked oligosaccharides of the alpha subunit in the secretion and assembly of human chorionic gonadotrophin. [PDF]

, 1988
Martin M. Matzuk, Irving Boime
openalex   +1 more source

The Human Cardiac “Age‐OME”: Age‐Specific Changes in Myocardial Molecular Expression

Aging Cell, EarlyView.
A multi‐omics analysis was performed to uncover the molecular landscape of human cardiac ageing. We report several insights for the first time: a decrease in proteins composing the structural machinery of the heart; a likely compensatory increase in energetic flux and redox reductive capacity; and an increase in lysosomal activity.
Cassandra Malecki, Giovanni Guglielmi, Benjamin Hunter, Dylan Harney, Yen Chin Koay, Anthony. S. Don, Oscar Han, Jasmine Khor, Lisa Nguyen, Michael Pan, Peter Gawthrop, Nathan Isles, Joshua Chung, Robert. D. Hume, Matthew Taper, XiaoSuo Wang, Mark Larance, Fabian Spill, Vijay Rajagopal, John F. O’Sullivan, Sean Lal   +20 more
wiley   +1 more source