Results 261 to 270 of about 202,771 (390)

The Metabolic Transition Between Fasting and Feeding Alters Aging‐Associated Metabolites, Lowers BCAAs, and Stimulates FGF21 Production in Humans

open access: yesAging Cell, EarlyView.
In humans, prolonged fasting profoundly remodels the plasma metabolome while maintaining stable levels of BCAA and FGF21. Upon refeeding, plasma BCAAs (valine, isoleucine, and leucine) decline, reflecting tissue uptake and coinciding with a surge in FGF21, independent of insulin and glucose.
Maria Lastra Cagigas   +10 more
wiley   +1 more source

In vitro and molecular modeling insights into α-amylase inhibition by tamarind seed-derived trypsin inhibitor: Implications for hyperglycemic control. [PDF]

open access: yesPLoS One
de Souza LAL   +11 more
europepmc   +1 more source

O-GlcNAc Transferase Recognizes Protein Substrates Using an Asparagine Ladder in the Tetratricopeptide Repeat (TPR) Superhelix.

open access: yesJournal of the American Chemical Society, 2018
Zebulon G. Levine   +5 more
semanticscholar   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

open access: yesAndrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos   +4 more
wiley   +1 more source

Asparagine-modified magnetic graphene oxide as efficient green nanocatalyst for synthesis of chromenes and pyrano pyrazoles derivatives. [PDF]

open access: yesSci Rep
Khaleghiabbasabadi M   +7 more
europepmc   +1 more source

Early prediction of subsequent peg‐asparaginase inactivation in acute lymphoblastic leukaemia patients—A NOPHO ALL2008 study

open access: yesBritish Journal of Haematology, EarlyView.
Summary Polyethylene glycol (peg)‐asparaginase plays a crucial role in acute lymphoblastic leukaemia (ALL) treatment, yet its associated toxicity often leads to treatment discontinuation, elevating relapse risk. Hypersensitivity with inactivation of asparaginase is common and often associated with severe allergic reactions.
Merete Dam   +18 more
wiley   +1 more source

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