Results 361 to 370 of about 202,771 (390)

Role of pancreatic L-asparagine synthetase in homeostasis of L-asparagine.

American Journal of Physiology-Endocrinology and Metabolism, 1979
L-Asparagine synthetase from mouse pancreas was found to be associated principally with the exocrine pancreas and to be dependent on the age of the animal, but not on gender, diet, or the presence of tumor under the conditions examined. The function of the pancreatic enzyme appears to be to supply L-asparagine for the synthesis of pancreatic proteins ...
H A Milman, David A. Cooney, D M Young
openaire   +3 more sources

Worsening of Seizures After Asparagine Supplementation in a Child with Asparagine Synthetase Deficiency

Pediatric Neurology, 2016
Asparagine synthetase deficiency is an autosomal recessive neurometabolic disorder characterized clinically by severe congenital microcephaly, global developmental delay, intractable epilepsy, and motor impairment in the form of spastic quadriparesis. Diagnosis is confirmed by findings of low cerebral spinal fluid or plasma asparagine in addition to a ...
Muhammad Talal Alrifai, Muhammad Talal Alrifai, Majid Alfadhel, Majid Alfadhel   +3 more
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Activating T cells with asparagine

Science Signaling, 2021
Extracellular asparagine stimulates Lck to promote T cell responses to cancer cells and infection.
openaire   +2 more sources

Properties and Physiological Role of Asparagine and Glutamine, with a new Interpretation of the Structure of Asparagine

Nature, 1952
Properties and Physiological Role of Asparagine and Glutamine, with a new Interpretation of the Structure of ...
F. C. Steward, John F. Thompson, John F. Thompson   +2 more
openaire   +3 more sources

Importance of asparagine-61 and asparagine-109 to the angiogenic activity of human angiogenin

Biochemistry, 1992
Two distinct regions of angiogenin are critical for angiogenic activity: a catalytic site capable of cleaving RNA and a noncatalytic site, encompassing residues 60-68, which may bind to an endothelial cell-surface receptor [Hallahan, T. W., Shapiro, R., & Vallee, B. L. (1991) Proc. Natl. Acad. Sci. U.S.A. 88, 2222-2226].
Daniel J. Strydom, Robert Shapiro, Terrence W. Hallahan, Bert L. Vallee   +3 more
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The relationship between “strepogenin” and asparagine

Archives of Biochemistry and Biophysics, 1953
Abstract 1. 1. During the first 20 hr. of incubation in a strepogenin-free medium, asparagine had a slight stimulatory effect on the growth of Lactobacillus casei. Similar effects were observed with glutamine and aspartic acid. 2. 2. The stimulatory effect of partially hydrolyzed insulin, used as a source of strepogenin, was considerably ...
S.P. Mistry, E. Kodicek
openaire   +3 more sources

Synthesis of asparagine-linked bacillosamine

Carbohydrate Research, 2006
Various types of protein glycosylation have been identified from prokaryotes. Recent investigations have revealed the presence of N-linked glycoproteins in the pathogenic bacterium, Campylobacter jejuni. The structure of this glycan is unique, consisting of 5 GalNAc and 1 Glc, in addition to 2,4-diacetamido-2,4,6-trideoxy-d-glucopyranose (bacillosamine;
Akihiro Ishiwata, Mohammed N. Amin, Yukishige Ito   +2 more
openaire   +3 more sources

Oxygen-Dependent Asparagine Hydroxylation

2004
Publisher Summary This chapter discusses oxygen-dependent asparagine hydroxylation. Asparagine hydroxylation occurs adjacent to the C-terminal transcriptional activation domain (CAD) of the Hypoxia-induced factor (HIF), repressing transactivation by blocking the interaction of HIF with the transcriptional coactivator p300 and prevents activation of ...
Peet, Daniel J., Lando, David, Whelan, Dean A., Whitelaw, Murray L., Gorman, Jeffrey J.   +4 more
openaire   +4 more sources

Assembly of asparagine-linked oligosaccharides.

Annual Review of Biochemistry, 1985
R. Kornfeld, S. Kornfeld
semanticscholar   +1 more source

Advances in Asparagine Metabolism

2017
Asparagine is a key compound in the nitrogen metabolism of plants. It acts as a major form of nitrogen storage and transport to sink tissues. In the past 20 years, tremendous progress has been made in our understanding of the enzymology of asparagine metabolic pathways and of the biological role of asparagine metabolic enzymes in higher plants, by ...
Frédéric Marsolais, Frédéric Marsolais, Shrikaar Kambhampati, Shrikaar Kambhampati, Ebenezer Ajewole, Ebenezer Ajewole   +5 more
openaire   +2 more sources