Redox Biology, 2017 No-caloric sweeteners, such as aspartame, are widely used in various food and beverages to prevent the increasing rates of obesity and diabetes mellitus, acting as tools in helping control caloric intake.
Isabela Finamor +2 more
exaly +3 more sources
Revisiting the safety of aspartame [PDF]
Nutrition Reviews, 2017 Aspartame is a synthetic dipeptide artificial sweetener, frequently used in foods, medications, and beverages, notably carbonated and powdered soft drinks. Since 1981, when aspartame was first approved by the US Food and Drug Administration, researchers have debated both its recommended safe dosage (40 mg/kg/d) and its general safety to organ systems ...
Arbind Kumar Choudhary +2 more
exaly +3 more sources
No indication of histological changes in embryonic somatosensory cortex development upon maternal aspartame consumption in mice [PDF]
npj Science of FoodNon-nutritive sweeteners are widely used in multiple diets and are considered a healthy alternative for pregnant women reducing sugar consumption, thereby preventing maternal obesity and gestational diabetes.
Liliia Andriichuk, Takashi Namba
doaj +2 more sources
Aspartame and ischemic stroke: unraveling the molecular link through network toxicology and molecular docking analysis [PDF]
Scientific ReportsAspartame, a widely used artificial sweetener, remains controversial due to neurotoxic risks from its metabolites—phenylalanine, aspartic acid, and methanol.
Tianyu Zhang +4 more
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Metagenomics and transcriptomics analysis of aspartame’s impact on gut microbiota and glioblastoma progression in a mouse model [PDF]
Scientific ReportsAspartame, a widely used artificial sweetener, has been extensively studied for its potential health effects. Emerging evidence suggests that aspartame intake may directly impact the composition and function of the intestinal microbiota, which could ...
Kaikai Meng +8 more
doaj +2 more sources
BioLink, 2022 Aspartame is an artificial sweetener in foods and beverages. Continuous use of aspartame will result in oxidative stress in the liver. So we need antioxidants from outside the body such as periwinkle leaves.This study aims to determine the effect of ...
Mahriani Mahriani +2 more
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Genotoxicity of Aspartame [PDF]
Drug and Chemical Toxicology, 2004 In the present study, the genotoxic effects of the low-calorie sweetener aspartame (ASP), which is a dipeptide derivative, was investigated using chromosome aberration (CA) test, sister chromatid exchange (SCE) test, micronucleus test in human lymphocytes and also Ames/Salmonella/ microsome test.
Rencüzogullari E. +6 more
openaire +2 more sources
Low-dose aspartame consumption differentially affects gut microbiota-host metabolic interactions in the diet-induced obese rat. [PDF]
PLoS ONE, 2014 Aspartame consumption is implicated in the development of obesity and metabolic disease despite the intention of limiting caloric intake. The mechanisms responsible for this association remain unclear, but may involve circulating metabolites and the gut ...
Marie S A Palmnäs +7 more
doaj +1 more source
Spirulina platensis and alpha lipoic acid are protective against the deleterious effects of aspartame on the liver and kidneys of rabbits [PDF]
Benha Veterinary Medical Journal, 2019 Spirulina platensis and alpha lipoic acid are the most important antioxidants. The purpose of this study was to explore the adverse effect of artificial sweetener (Aspartame) and the protective role of alpha lipoic acid and spirulina in alleviating the ...
Samy Hussein +3 more
doaj +1 more source
The Effect of Aspartame on Albino Rat’s Placenta and the Possible Protective Effect of Ginger: Histological and Teratogenic Study [PDF]
The Egyptian Journal of Histology, 2023 used throughout the world, its metabolites can cross the placenta and cause change on its structure. Ginger is a plant used in the treatment of vomiting during pregnancy. Its extracts were reported to have an antioxidant action.Aim of the Work: Assessing
Ahmed Ayad +4 more
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