Results 181 to 190 of about 20,129 (222)

Aspartame and aspartame derivatives effect human thrombin catalytic activity

Biophysical Chemistry, 2004
The study of small Asp-Phe analogs was undertaken since this dipeptide sequence is critical in fibrinogen recognition and catalysis. The inhibition of clotting activity by Asp-Phe-methyl ester (aspartame), formyl-Asp-Phe-methyl ester and acetyl-Asp-Phe was biphasic in all cases, indicating the presence of at least two binding sites.
Julie E, Scheffler, Lawrence J, Berliner
openaire   +2 more sources

Insight into the mechanism of aspartame‐induced toxicity in male reproductive system following long‐term consumption in mice model

Environmental Toxicology, 2020
Aspartame is one of the most common consumed artificial sweeteners utilized in many food products and beverages. It has been indicated that long‐term consumption of aspartame leads to reproductive toxicity but its mechanism is not well‐clear.
H. Anbara, Mohammad Taghi Sheibani, M. Razi, Mehdi Kian   +3 more
semanticscholar   +1 more source

Long-Term Effect of Aspartame on Male Reproductive System: Evidence for Testicular Histomorphometrics, Hsp70-2 Protein Expression and Biochemical Status

International Journal of Fertility and Sterility, 2020
Background Aspartame is one of the most commonly consumed artificial sweeteners that is widely used in foodstuffs. There are many debatable reports about aspartame toxicity in different tissues; however, on the subject of its effects on the reproductive ...
H. Anbara, Mohammad Taghi Sheibani, M. Razi   +2 more
semanticscholar   +1 more source

Conformational flexibility of aspartame

Peptide Science, 2016
ABSTRACTL‐Aspartyl‐L‐phenylalanine methyl ester, better known as aspartame, is not only one of the most used artificial sweeteners, but also a very interesting molecule with respect to the correlation between molecular structure and taste. The extreme conformational flexibility of this dipeptide posed a huge difficulty when researchers tried to use it ...
Claudio, Toniolo, Pierandrea, Temussi
openaire   +2 more sources

Aspartame

Nutrition & Food Science, 1984
This new sweetener has an excellent flavour but some newspaper stories have questioned its ...
openaire   +1 more source

Aspartame-lnduced Urticaria

Annals of Internal Medicine, 1986
Excerpt Aspartame (NutraSweet; G.D. Searle & Co., Skokie, Illinois), the dipeptide composed of aspartic acid and the methyl ester of phenylalanine, is a low-calorie artificial sweetener 180 times s...
openaire   +2 more sources

Self-Assembly of Artificial Sweetener Aspartame Yields Amyloid-like Cytotoxic Nanostructures.

ACS Nano, 2019
Recent reports have revealed the intrinsic propensity of single aromatic metabolites to undergo self-assembly and form nanostructures of amyloid nature.
B. Anand, K. Prajapati, K. Dubey, Naseem Ahamad, D. S. Shekhawat, P. Rath, G. K. Joseph, K. Kar   +7 more
semanticscholar   +1 more source

Aspartame-induced lobular panniculitis

Journal of the American Academy of Dermatology, 1991
Textbooks,1,2 papers,3 and, more recently, this JOURNAL4 have stated that trichomycosis rarely occurs on pubic, scrotal, and perineal hair. This was not our impression from practice in the United Arab Emirates, so we conducted a survey of patients attending the Dermatology Clinics at Tawam University Hospital, AI Ain, Abu Dhabi, from Oct. 15 until Dec.
D P, McCauliffe, K, Poitras
openaire   +2 more sources

Aspartame-lnduced Granulomatous Panniculitis

Annals of Internal Medicine, 1985
Excerpt The Low-Calorie Artificial Sweetener, aspartame (NutraSweet; G.D. Searle & Co., Skokie, Illinois), a synthetic combination of aspartic acid and the methyl ester of phenylalanine, is current...
openaire   +2 more sources

Aspartame*

Reactions, 1985
  +4 more sources