Metabolic and biochemical profiling reveals phenotypic heterogeneity in Zucker diabetic fatty rats
Genetically uniform Zucker Diabetic Fatty (ZDF) rats spontaneously develop four distinct metabolic phenotypes despite identical housing and diet conditions. Each phenotype exhibits unique biomarker signatures encompassing glucose homeostasis, insulin secretion, polyol pathway activation, oxidative stress, inflammatory cytokines, and neurotrophic ...
Marek Lepáček +3 more
wiley +1 more source
Modulation of nitrogen metabolising enzymes and the photosynthetic pigments in wheat upon exogenous application of marigold leachates. [PDF]
Mir RA +4 more
europepmc +1 more source
Transcriptome sequencing identified secreted phosphoprotein 1 (SPP1) as a crucial target through which methylophiopogonanone A (MOA) ameliorates pulmonary fibrosis. Molecular docking and microscale thermophoresis (MST) assays confirmed a favorable binding affinity between MOA and SPP1.
Fan Yang +10 more
wiley +1 more source
Effect of coffee and coffee extract on liver function test in non-alcoholic fatty liver disease patients, a systematic review and meta-analysis. [PDF]
Sayedi M, Chaghazardi Z, Sharifi A.
europepmc +1 more source
The toxicity of drugs and other related agents attracts considerable attention from basic scientists to clinicians. Humankind has been passionate about the availability of cheap and readily available agent against organotoxicity.
S. B. Olukayode, S. O. Innih
doaj
Drug induced liver injury in HIV patients on dolutegravir based antiretroviral therapy regimens in Wolaita Sodo comprehensive specialized hospital. [PDF]
Abraham F, Toma A, Balcha T, Tigabu BM.
europepmc +1 more source
Impact of age on autoimmune hepatitis: A comparative study of patients diagnosed before and after sixty. [PDF]
Delgado J +4 more
europepmc +1 more source
The Role of Low-Protein and Cassava-Cyanide Intake in the Aetiology of Tropical Pancreatitis [PDF]
Anoruo, K. +3 more
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